(Q36380314)

English

Commitment of immature CD4+8+ thymocytes to the CD4 lineage requires CD3 signaling but does not require expression of clonotypic T cell receptor (TCR) chains

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

Commitment of immature CD4+8+ thymocytes to the CD4 lineage requires CD3 signaling but does not require expression of clonotypic T cell receptor (TCR) chains (English)

1 reference

Europe PubMed Central

13 August 2017

0 references

author name string

Suzuki H

1

1 reference

Europe PubMed Central

13 August 2017

Shinkai Y

2

1 reference

Europe PubMed Central

13 August 2017

Granger LG

3

1 reference

Europe PubMed Central

13 August 2017

Alt FW

4

1 reference

Europe PubMed Central

13 August 2017

Love PE

5

1 reference

Europe PubMed Central

13 August 2017

Singer A

6

1 reference

Europe PubMed Central

13 August 2017

language of work or name

0 references

publication date

1 July 1997

1 reference

Europe PubMed Central

13 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

13 August 2017

186

1 reference

Europe PubMed Central

13 August 2017

1

1 reference

Europe PubMed Central

13 August 2017

17-23

1 reference

Europe PubMed Central

13 August 2017

Lineage commitment in the thymus: only the most differentiated (TCRhibcl-2hi) subset of CD4+CD8+ thymocytes has selectively terminated CD4 or CD8 synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

Receptors and signals in early thymic selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

CD4/CD8 lineage commitment: back to instruction?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

A challenge to the instructive model of positive selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

Sublethal gamma-radiation induces differentiation of CD4-/CD8- into CD4+/CD8+ thymocytes without T cell receptor beta rearrangement in recombinase activation gene 2-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

Identification of a monoclonal antibody specific for a murine T3 polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

CD3 zeta dependence of the CD2 pathway of activation in T lymphocytes and natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

30 September 2017

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

28 June 2018

CD8/CD4 lineage commitment occurs by an instructional/default process followed by positive selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

28 June 2018

Development of mature CD8+ thymocytes: selection rather than instruction?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

28 June 2018

Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

28 June 2018

Intermediate steps in thymic positive selection. Generation of CD4-8+ T cells in culture from CD4+8+, CD4int8+, and CD4+8int thymocytes with up-regulated levels of TCR-CD3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

28 June 2018

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

28 June 2018

Signal transduction by the CD2 antigen in T cells and natural killer cells: requirement for expression of a functional T cell receptor or binding of antibody Fc to the Fc receptor, Fc gamma RIIIA (CD16)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

28 June 2018

Post-transcriptional regulation of early T cell development by T cell receptor signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

28 June 2018

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2198962

28 June 2018

Another view of the selective model of thymocyte selection.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

In vitro differentiation and commitment of CD4+ CD8+ thymocytes to the CD4 lineage, without TCR engagement.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

Differential induction of helper and killer T cells from isolated CD4+CD8+ thymocytes in suspension culture.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

CD3 epsilon and CD3 zeta cytoplasmic domains can independently generate signals for T cell development and function.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

Thy-1-mediated T-cell activation requires co-expression of CD3/Ti complex

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

T cell development in mice that lack the zeta chain of the T cell antigen receptor complex

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.1.17

21 January 2018

Identifiers

10.1084/JEM.186.1.17

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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