(Q36381508)

English

The use of the Chandler loop to examine the interaction potential of NXY-059 on the thrombolytic properties of rtPA on human thrombi in vitro

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

The use of the Chandler loop to examine the interaction potential of NXY-059 on the thrombolytic properties of rtPA on human thrombi in vitro (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

N R Moore

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

C Mattsson

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

H Jonasson

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

A R Green

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

N A Booth

6

1 reference

Europe PubMed Central

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9 January 2020

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publication date

5 November 2007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

153

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1

1 reference

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9 January 2020

124-131

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

TAFIa, PAI-1 and alpha-antiplasmin: complementary roles in regulating lysis of thrombi and plasma clots

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Neuroprotection and thrombolysis: combination therapy in acute ischaemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Therapeutic strategies for the treatment of stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

NXY-059 for acute ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

1,026 experimental treatments in acute stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Free radical trapping as a therapeutic approach to neuroprotection in stroke: experimental and clinical studies with NXY-059 and free radical scavengers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Nitrones as neuroprotective agents in cerebral ischemia, with particular reference to NXY-059.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Antithrombotic efficacy of a novel factor Xa inhibitor, FXV673, in a canine model of coronary artery thrombolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Contribution of in vivo models of thrombosis to the discovery and development of novel antithrombotic agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Inhibitory effects of lysine analogues on t-PA induced whole blood clot lysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Tissue plasminogen activator for acute ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

30 September 2017

Investigating the free radical trapping ability of NXY-059, S-PBN and PBN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

28 June 2018

Systematic review of evidence on thrombolytic therapy for acute ischaemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

28 June 2018

Plasminogen activator inhibitor-1 released from activated platelets plays a key role in thrombolysis resistance. Studies with thrombi generated in the Chandler loop.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

28 June 2018

An examination of the fluid mechanics and thrombus formation time parameters in a Chandler rotating loop system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

28 June 2018

Pharmacokinetics of antigen and activity of recombinant tissue-type plasminogen activator after infusion in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

28 June 2018

"Plasminogen steal" and clot lysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

28 June 2018

NXY-059, a free radical--trapping agent, substantially lessens the functional disability resulting from cerebral ischemia in a primate species

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0707543

21 January 2018

Fibrinolytic properties of lysine-derivatized polyethylene in contact with flowing whole blood (Chandler loop model).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0707543

21 January 2018

Extending the window for acute stroke treatment: thrombolytics plus CNS protective therapies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

21 September 2018

Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

21 September 2018

Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

21 September 2018

Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

21 September 2018

Effects of liver blood flow on the pharmacokinetics of tissue-type plasminogen activator (alteplase) during thrombolysis in patients with acute myocardial infarction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199381

21 September 2018

A study of artificial thrombi produced by a modification of Chandler's method

1 reference

https://pubmed.ncbi.nlm.nih.gov/17982476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and fibrin specificity of alteplase during accelerated infusions in acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17982476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NXY-059 for the treatment of acute ischemic stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/17982476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombus lysis by uPA, scuPA and tPA is regulated by plasma TAFI

1 reference

https://pubmed.ncbi.nlm.nih.gov/17982476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombi formed in a Chandler loop mimic human arterial thrombi in structure and RAI-1 content and distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/17982476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmin is a specific stimulus of the 5-lipoxygenase pathway of human peripheral monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17982476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of pharmacokinetics of lanoteplase and alteplase during acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17982476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNK-tissue plasminogen activator compared with front-loaded alteplase in acute myocardial infarction: results of the TIMI 10B trial. Thrombolysis in Myocardial Infarction (TIMI) 10B Investigators

1 reference

https://pubmed.ncbi.nlm.nih.gov/17982476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro thrombotic coagulation of the blood; a method for producing a thrombus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17982476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0707543

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17982476%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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