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The immunological consequences of injury
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
The immunological consequences of injury
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
main subject
acute inflammatory response to non-antigenic stimulus
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0002525
immunology
1 reference
based on heuristic
inferred from title
author name string
Ni Choileain N
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
Redmond HP
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
publication date
1 February 2006
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
published in
Journal of the Royal College of Surgeons of Edinburgh
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
volume
4
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
page(s)
23-31
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
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The effects of injury on the adaptive immune response
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7 January 2021
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Update on the mechanisms of immune suppression of injury and immune modulation
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Crossref
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7 January 2021
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Severe injury triggers antigen-specific T-helper cell dysfunction
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7 January 2021
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Clinical review: immunodepression in the surgical patient and increased susceptibility to infection
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Immune deficiency following thermal trauma is associated with apoptotic cell death
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Multiple organ failure in patients with thermal injury.
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Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): are we winning the battle?
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Current treatment of severely burned patients
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7 January 2021
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Experience with polymicrobial sepsis in a regional burn unit
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Differential expression of transforming growth factor-beta receptors in a rabbit zone II flexor tendon wound healing model
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Multiple organ failure. Pathophysiology and potential future therapy
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7 January 2021
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Is circulating endotoxin the trigger for the systemic inflammatory response syndrome seen after injury?
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Macrophage elimination increases bacterial translocation and gut-origin septicemia but attenuates symptoms and mortality rate in a model of systemic inflammation
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Inadequate interleukin 2 production. A fundamental immunological deficiency in patients with major burns
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7 January 2021
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Depression of cellular immunity after major injury. Its association with posttraumatic complications and its reversal with immunomodulation
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7 January 2021
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Mechanism of enhanced susceptibility to sepsis following hemorrhage. Interleukin-10 suppression of T-cell response is mediated by eicosanoid-induced interleukin-4 release.
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7 January 2021
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Dominance of T-helper 2-type cytokines after severe injury.
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7 January 2021
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Major injury leads to predominance of the T helper-2 lymphocyte phenotype and diminished interleukin-12 production associated with decreased resistance to infection
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7 January 2021
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Etiology of multiple organ failure
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7 January 2021
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Thermal injury alters macrophage responses to prostaglandin E2: contribution to the enhancement of inducible nitric oxide synthase activity
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Crossref
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7 January 2021
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Mechanisms of altered monocyte prostaglandin E2 production in severely injured patients
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Crossref
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7 January 2021
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inferred from DOI database lookup
Burn-induced nitric oxide release in humans
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Crossref
reference URL
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7 January 2021
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Thermal injury-induced immunosuppression in mice: the role of macrophage-derived reactive nitrogen intermediates
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Crossref
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7 January 2021
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The roles of macrophage (M phi) and PGE-2 in postburn immunosuppression
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7 January 2021
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Modulation of macrophage hyperactivity improves survival in a burn-sepsis model
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7 January 2021
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Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses
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Alterations of acute phase reaction and cytokine production in patients following severe burn injury.
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Modulation of types I and II acute phase reactants with insulin-like growth factor-1/binding protein-3 complex in severely burned children
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7 January 2021
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Tumor necrosis factor and immunopathology
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7 January 2021
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Cachectin/TNF production in experimental burns and Pseudomonas infection
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Plasma cytokines after thermal injury and their relationship to infection
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7 January 2021
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Plasma cytokine levels in patients with severe burn injury--with reference to the relationship between infection and prognosis
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7 January 2021
based on heuristic
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Concentrations of cytokines in plasma of patients with large burns: their relation to time after injury, burn size, inflammatory variables, infection, and outcome
1 reference
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Crossref
reference URL
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7 January 2021
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Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group.
1 reference
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Crossref
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7 January 2021
based on heuristic
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Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: a multicenter, randomized, placebo-controlled, dose-ranging study.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Acute ethanol exposure prior to thermal injury results in decreased T-cell responses mediated in part by increased production of IL-6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-6 in the injured patient. Marker of injury or mediator of inflammation?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of immune responses by TGF-beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor type beta induces monocyte chemotaxis and growth factor production
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Serum TGF-beta in thermally injured rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta impairs postburn immunoglobulin production by limiting B-cell proliferation, but not cellular synthesis
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta1 and splenocyte apoptotic cell death after burn injuries
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The 1997 Moyer Award. Cytokine production in patients with hypertrophic burn scars.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A study of cytokines in burn blister fluid related to wound healing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide--a new endogenous immunomodulator.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of lymphocyte functions by nitric oxide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of nitrogen oxide production following experimental thermal injury in rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide production is intensely and persistently increased in tissue by thermal injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide and macrophage function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prostaglandin E2 regulates inducible nitric oxide synthase in the murine macrophage cell line J774.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of PGE2 and of agents that raise cAMP levels on macrophage activation induced by IFN-gamma and TNF-alpha.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes in gut mucosal nitric oxide synthase (NOS) activity after thermal injury and its relation with barrier failure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prostaglandins and the Inflammatory Response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical significance of the alterations of plasma prostaglandin E2 (PGE2) in severely burned patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclooxygenase isoenzymes and newer therapeutic potential for selective COX-2 inhibitors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human cyclooxygenase-2 cDNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prostaglandin E2 primes naive T cells for the production of anti-inflammatory cytokines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of prostaglandin E2 in immune suppression following injury.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclooxygenase 2-mediated suppression of macrophage interleukin-12 production after thermal injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential Regulation of Cyclo-Oxygenase-1 and Cyclo-Oxygenase-2 Gene Expression by Lipopolysaccharide Treatmentin vivoin the Rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insights into the role of gammadelta T lymphocytes in the immunopathogenic response to thermal injury
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclooxygenase-2 inhibitor NS-398 improves survival and restores leukocyte counts in burn infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Blocking prostaglandin E2 after trauma attenuates pro-inflammatory cytokines and improves survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An imbalance in T-helper cell subsets alters immune response after cardiac surgery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormalities of antibody production after thermal injury. An association with reduced interleukin 2 production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody formation after murine injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of sepsis with an immunosuppressive polypeptide in the serum of burn patients.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anergy, immunosuppressive serum, and impaired lymphocyte blastogenesis in burn patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impairment of specific host defense mechanisms in patients with chronic post-traumatic osteomyelitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-12 and its role in the generation of TH1 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of IL-4, IL-10, and TNF-alpha in the immune suppression induced by ultraviolet radiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A relationship between the generation of burn-associated type 2 T cells and their antagonistic cells in thermally injured mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Determination of the immunoglobulin E postoperative variation as a measure of surgical injury.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Th2 response as monitored by CRTH2 or CCR3 expression is severely decreased during septic shock
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Injury, sepsis, and the regulation of Toll-like receptor responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-10 Is Associated with the Development of Sepsis in Trauma Patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
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Major injury induces increased production of interleukin-10 by cells of the immune system with a negative impact on resistance to infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
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CD4+CD25+ regulatory T cells control innate immune reactivity after injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
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Glucocorticoids and muscle catabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
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Natural adjuvants: endogenous activators of dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980018-1
retrieved
7 January 2021
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Identifiers
DOI
10.1016/S1479-666X(06)80018-1
0 references
PubMed ID
16459497
1 reference
stated in
Europe PubMed Central
PubMed ID
16459497
retrieved
13 August 2017
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