(Q36389801)

English

Quetiapine Inhibits Microglial Activation by Neutralizing Abnormal STIM1-Mediated Intercellular Calcium Homeostasis and Promotes Myelin Repair in a Cuprizone-Induced Mouse Model of Demyelination

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4 March 2020

Quetiapine Inhibits Microglial Activation by Neutralizing Abnormal STIM1-Mediated Intercellular Calcium Homeostasis and Promotes Myelin Repair in a Cuprizone-Induced Mouse Model of Demyelination (English)

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4 March 2020

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microglial inhibitor

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based on heuristic

inferred from title

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4 March 2020

author name string

Hanzhi Wang

1

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4 March 2020

Shubao Liu

2

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4 March 2020

Yanping Tian

3

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4 March 2020

Xiyan Wu

4

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4 March 2020

Yangtao He

5

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4 March 2020

Chengren Li

6

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4 March 2020

Michael Namaka

7

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4 March 2020

Hongli Li

9

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4 March 2020

Lan Xiao

10

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4 March 2020

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21 December 2015

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4 March 2020

Frontiers in Cellular Neuroscience

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4 March 2020

9

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4 March 2020

492

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4 March 2020

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Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-κB and AP-1 Activation

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30 September 2017

18β-glycyrrhetinic acid suppresses experimental autoimmune encephalomyelitis through inhibition of microglia activation and promotion of remyelination

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STIM and ORAI proteins in the nervous system

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Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination

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30 September 2017

Stim and Orai proteins in neuronal Ca(2+) signaling and excitability

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30 September 2017

Inhibition of store-operated calcium entry in microglia by helminth factors: implications for immune suppression in neurocysticercosis

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30 September 2017

Cellular and molecular neuropathology of the cuprizone mouse model: clinical relevance for multiple sclerosis

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30 September 2017

Microglial intracellular Ca(2+) signaling as a target of antipsychotic actions for the treatment of schizophrenia

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30 September 2017

Microglial pathology

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30 September 2017

Helminth induced suppression of macrophage activation is correlated with inhibition of calcium channel activity

1 reference

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30 September 2017

Schizophrenia: susceptibility genes and oligodendroglial and myelin related abnormalities

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30 September 2017

The human side of microglia

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30 September 2017

Microglial calcium signaling in the adult, aged and diseased brain

1 reference

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30 September 2017

Improving myelin/oligodendrocyte-related dysfunction: a new mechanism of antipsychotics in the treatment of schizophrenia?

1 reference

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30 September 2017

Neurotransmitters, psychotropic drugs and microglia: clinical implications for psychiatry

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30 September 2017

Quetiapine, an atypical antipsychotic, is protective against autoimmune-mediated demyelination by inhibiting effector T cell proliferation

1 reference

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30 September 2017

Neuroinflammation in schizophrenia especially focused on the role of microglia

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30 September 2017

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30 September 2017

Recovery of behavioral changes and compromised white matter in C57BL/6 mice exposed to cuprizone: effects of antipsychotic drugs

1 reference

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30 September 2017

Possible role of BDNF-induced microglial intracellular Ca(2+) elevation in the pathophysiology of neuropsychiatric disorders

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30 September 2017

Physiology of microglia

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30 September 2017

Aripiprazole inhibits superoxide generation from phorbol-myristate-acetate (PMA)-stimulated microglia in vitro: implication for antioxidative psychotropic actions via microglia.

1 reference

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30 September 2017

Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy.

1 reference

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30 September 2017

Behavioral and neurobiological changes in C57BL/6 mouse exposed to cuprizone: effects of antipsychotics.

1 reference

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30 September 2017

ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+ entry in the immune system and beyond.

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30 September 2017

The Ca2+ release-activated Ca2+ current (I(CRAC)) mediates store-operated Ca2+ entry in rat microglia

1 reference

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30 September 2017

Regulation and function of NF-kappaB transcription factors in the immune system

1 reference

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30 September 2017

Quetiapine in the treatment of schizophrenia and related disorders

1 reference

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30 September 2017

Quetiapine alleviates the cuprizone-induced white matter pathology in the brain of C57BL/6 mouse.

1 reference

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30 September 2017

The antipsychotic spiperone attenuates inflammatory response in cultured microglia via the reduction of proinflammatory cytokine expression and nitric oxide production

1 reference

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30 September 2017

Inhibitory effects of aripiprazole on interferon-gamma-induced microglial activation via intracellular Ca2+ regulation in vitro.

1 reference

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30 September 2017

Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review

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30 September 2017

The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions

1 reference

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30 September 2017

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30 September 2017

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30 September 2017

Deleterious role of IFNgamma in a toxic model of central nervous system demyelination

1 reference

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30 September 2017

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

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30 September 2017

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30 September 2017

STIM1, an essential and conserved component of store-operated Ca2+ channel function

1 reference

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30 September 2017

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30 September 2017

Review of quetiapine and its clinical applications in schizophrenia

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30 September 2017

The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system.

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30 September 2017

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30 September 2017

Quetiapine mitigates the neuroinflammation and oligodendrocyte loss in the brain of C57BL/6 mouse following cuprizone exposure for one week.

1 reference

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28 June 2018

Quetiapine attenuates glial activation and proinflammatory cytokines in APP/PS1 transgenic mice via inhibition of nuclear factor-κB pathway

1 reference

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28 June 2018

Microglial inhibitory factor (MIF/TKP) mitigates secondary damage following spinal cord injury

1 reference

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28 June 2018

Neuroinflammation in schizophrenia-related psychosis: a PET study.

1 reference

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28 June 2018

Behavioral and neurobiological changes in C57BL/6 mice exposed to cuprizone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685920

28 June 2018

Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control of release function.

1 reference

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28 June 2018

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

1 reference

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28 June 2018

IL-6, IL-18, sIL-2R, and TNFα proinflammatory markers in depression and schizophrenia patients who are free of overt inflammation.

1 reference

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21 September 2018

STIM1, STIM2, and Orai1 regulate store-operated calcium entry and purinergic activation of microglia.

1 reference

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21 September 2018

Regulation of phagocytosis and cytokine secretion by store-operated calcium entry in primary isolated murine microglia.

1 reference

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21 September 2018

Different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: further evidence for disease course-related immune alterations?

1 reference

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21 September 2018

Quetiapine enhances oligodendrocyte regeneration and myelin repair after cuprizone-induced demyelination.

1 reference

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21 September 2018

Magnetic resonance imaging and histological evidence for the blockade of cuprizone-induced demyelination in C57BL/6 mice.

1 reference

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21 September 2018

Haloperidol promotes proliferation but inhibits differentiation in rat oligodendrocyte progenitor cell cultures

1 reference

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21 September 2018

Haloperidol activates quiescent oligodendroglia precursor cells in the adult mouse brain.

1 reference

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21 September 2018

Demyelination in the juvenile period, but not in adulthood, leads to long-lasting cognitive impairment and deficient social interaction in mice.

1 reference

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21 September 2018

Quetiapine regulates neurogenesis in ischemic mice by inhibiting NF-kappaB p65/p50 expression

1 reference

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21 September 2018

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21 September 2018

Quetiapine facilitates oligodendrocyte development and prevents mice from myelin breakdown and behavioral changes.

1 reference

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21 September 2018

Interleukin-1beta, interleukin-18, and interferon-gamma expression in the cerebrospinal fluid of premature infants with posthemorrhagic hydrocephalus--markers of white matter damage?

1 reference

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21 September 2018

Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicide.

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21 September 2018

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1 reference

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21 September 2018

Interleukin-1 regulates proliferation and differentiation of oligodendrocyte progenitor cells.

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21 September 2018

Altered IL-2, IL-6 and IL-8 serum levels in schizophrenia patients with tardive dyskinesia

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21 January 2018

Quetiapine reduces microglial number in the hippocampus of a transgenic mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26732345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FNCEL.2015.00492

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732345%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

Europe PubMed Central

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4 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26732345%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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