(Q36399144)

14 August 2017

Pathogenic profiles and molecular signatures of antinuclear autoantibodies rescued from NZM2410 lupus mice (English)

1 reference

14 August 2017

1 reference

Zhiyan Liang

1

1 reference

14 August 2017

Chun Xie

2

1 reference

14 August 2017

Cui Chen

3

1 reference

14 August 2017

Desi Kreska

4

1 reference

14 August 2017

Kelvin Hsu

5

1 reference

14 August 2017

Liunan Li

6

1 reference

14 August 2017

Xin J Zhou

7

1 reference

14 August 2017

Chandra Mohan

8

1 reference

14 August 2017

language of work or name

English

0 references

publication date

1 February 2004

1 reference

Journal of Experimental Medicine

14 August 2017

1 reference

14 August 2017

199

1 reference

14 August 2017

3

1 reference

14 August 2017

381-398

1 reference

Enhanced susceptibility to end-organ disease in the lupus-facilitating NZW mouse strain

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Alpha-actinin is a cross-reactive renal target for pathogenic anti-DNA antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Crystal structure of an antigen-binding fragment bound to single-stranded DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Anti-DNA and autoantibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Immunochemical, structural and translocating properties of anti-DNA antibodies from (NZBxNZW)F1 mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Light chain usage in anti-double-stranded DNA B cell subsets: role in cell fate determination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Studies on the structure, regulation, and pathogenic potential of anti-dsDNA antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

An in vitro assay for detection of glomerular binding IgG autoantibodies in patients with systemic lupus erythematosus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Heterogeneity and clinical significance of glomerular-binding antibodies in systemic lupus erythematosus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Nephritogenic autoantibodies in lupus: current concepts and continuing controversies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Ligand recognition by murine anti-DNA autoantibodies. II. Genetic analysis and pathogenicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Nephritogenic autoantibodies in systemic lupus erythematosus: immunochemical properties, mechanisms of immune deposition, and genetic origins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Structure-function studies on a polyreactive (natural) autoantibody. Polyreactivity is dependent on somatically generated sequences in the third complementarity-determining region of the antibody heavy chain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Sequencing and modeling of anti-DNA immunoglobulin Fv domains. Comparison with crystal structures.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Mutational analysis of an autoantibody: differential binding and pathogenicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Genetic and structural evidence for antigen selection of anti-DNA antibodies.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Structure-function correlates of autoantibodies to nucleic acids. Lessons from immunochemical, genetic and structural studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Preparation, characterization and crystallization of an antibody Fab fragment that recognizes RNA. Crystal structures of native Fab and three Fab-mononucleotide complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Structure of the DNA-Eco RI endonuclease recognition complex at 3 A resolution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

An autoantibody to single-stranded DNA: Comparison of the three-dimensional structures of the unliganded fab and a deoxynucleotide-fab complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Antibodies to histones in systemic lupus erythematosus and drug-induced lupus syndromes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

The role of somatic mutation in the pathogenic anti-DNA response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Selection of immunoglobulin variable regions in autoimmunity to DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Sequence-specific recognition of double helical nucleic acids by proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Molecular signatures of antinuclear antibodies-contributions of heavy chain CDR residues

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Influence of VH CDR3 arginine and light chain pairing on DNA reactivity of a bacterial DNA-induced anti-DNA antibody from a BALB/c mouse

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Structural and affinity studies of IgM polyreactive natural autoantibodies.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Murine glomerulotropic monoclonal antibodies are highly oligoclonal and exhibit distinctive molecular features.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Residues that mediate DNA binding of autoimmune antibodies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Molecular characterization of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. Differences from spontaneous anti-DNA in the content and location of VH CDR3 arginines

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Molecular analysis of spontaneous nephrotropic anti-laminin antibodies in an autoimmune MRL-lpr/lpr mouse

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Comparison of pathogenic and non-pathogenic murine antibodies to DNA: antigen binding and structural characteristics

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Light chain contribution to specificity in anti-DNA antibodies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Murine lupus glomerulotropic monoclonal antibodies exhibit differing specificities but bind via a common mechanism

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Restricted Ig variable region gene expression among Ly-1+ B cell lymphomas.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Ig H and L chain contributions to autoimmune specificities

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Synovium as a source of increased amino-terminal parathyroid hormone-related protein expression in rheumatoid arthritis. A possible role for locally produced parathyroid hormone-related protein in the pathogenesis of rheumatoid arthritis

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Comparison of structural characteristics of antisubnucleosome and anti-DNA monoclonal antibodies derived from lupus mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Molecular Signatures of Anti-nuclear Antibodies: Contributions of Specific Light Chain Residues and a Novel New Zealand BlackVκ1Germline Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

In vivo localization and pathological effects of passively transferred antibodies to type IV collagen and laminin in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Use of a novel elution regimen reveals the dominance of polyreactive antinuclear autoantibodies in lupus kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

DNA antibodies focus on the light chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Editors and editing of anti-DNA receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Characterization of anti-DNA B cells that escape negative selection.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Correlation between the amino acid position of arginine in VH-CDR3 and specificity for native DNA among autoimmune antibodies

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211797

Structural Features of Nephritogenic Lupus Autoantibodies

21 September 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Anti-subnucleosome reactivities in systemic lupus erythematosus (SLE) patients and their first-degree relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Nucleosome-restricted antibodies are detected before anti-dsDNA and/or antihistone antibodies in serum of MRL-Mp lpr/lpr and +/+ mice, and are present in kidney eluates of lupus mice with proteinuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Epistatic modifiers of autoimmunity in a murine model of lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Association of renal injury with increased oxygen free radical activity and altered nitric oxide metabolism in chronic experimental hemosiderosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Improved ion-exchange resins

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

The Influence of Variable-Region Somatic Mutations on the Specificity and Pathogenicity of Murine Monoclonal Anti-DNA Antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Significance of anti-nuclear and anti-extracellular matrix autoantibodies for albuminuria in murine lupus nephritis; a longitudinal study on plasma and glomerular eluates in MRL/l mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

High connectivity, natural antibodies preferentially use 7183 and QUPC 52 VH families

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Structural properties of a subset of nephritogenic anti-DNA antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Selection of recurrent V genes and somatic mutations in autoantibodies to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Diverse endogenous light chains contribute to basement membrane reactivity in nonautoimmune mice transgenic for an anti-laminin Ig heavy chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030132

Antigen specificity of anti-nuclear antibodies complexed to nucleosomes determines glomerular basement membrane binding in vivo

21 January 2018

1 reference

12 December 2020

Crystallization and structure determination of an autoimmune anti-poly(dT) immunoglobulin Fab fragment at 3.0 A resolution

1 reference

12 December 2020

Polyreactive autoantibodies are nephritogenic in murine lupus nephritis

1 reference

12 December 2020

Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney

1 reference

12 December 2020

Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo

1 reference

12 December 2020

Differences in expression of lupus nephritis in New Zealand mixed H-2z homozygous inbred strains of mice derived from New Zealand black and New Zealand white mice. Origins and initial characterization

1 reference

12 December 2020

Glomerular binding activity in MRL lpr serum consists of antibodies that bind to a DNA/histone/type IV collagen complex

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20030132

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

14757744

1 reference