(Q36404086)

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A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript

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Europe PubMed Central

PMC publication ID

14 August 2017

A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

U Storb

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

E L Klotz

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

J Hackett

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

K Kage

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

G Bozek

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

T E Martin

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

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publication date

1 August 1998

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Europe PubMed Central

PMC publication ID

14 August 2017

Journal of Experimental Medicine

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Europe PubMed Central

PMC publication ID

14 August 2017

188

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Europe PubMed Central

PMC publication ID

14 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

689-698

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

The role of DNA repair in somatic hypermutation of immunoglobulin genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

The molecular basis of somatic hypermutation of immunoglobulin genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

The characterization of a mammalian DNA structure-specific endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

Germinal centers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

Patterns of somatic mutations in immunoglobulin variable genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

On finding all suboptimal foldings of an RNA molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

Analysis of somatic mutations in kappa transgenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

30 September 2017

Somatic hypermutation of immunoglobulin genes is linked to transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

28 June 2018

Basic mechanisms of transcript elongation and its regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

28 June 2018

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

28 June 2018

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.4.689

21 January 2018

The RNA-DNA hybrid maintains the register of transcription by preventing backtracking of RNA polymerase.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.4.689

21 January 2018

Somatic hypermutation of an artificial test substrate within an Ig kappa transgene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

21 September 2018

Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

21 September 2018

Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213363

21 September 2018

The germinal center reaction

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.4.689

21 January 2018

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.4.689

21 January 2018

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.4.689

21 January 2018

Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.4.689

21 January 2018

The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.4.689

21 January 2018

Identifiers

10.1084/JEM.188.4.689

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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