(Q36408248)

14 August 2017

Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats (English)

1 reference

14 August 2017

0 references

Imir G Metushi

1

1 reference

14 August 2017

Tetsuya Nakagawa

series ordinal

2

1 reference

14 August 2017

Jack Uetrecht

series ordinal

3

1 reference

14 August 2017

16 October 2012

1 reference

Chemical Research in Toxicology

14 August 2017

1 reference

14 August 2017

25

1 reference

14 August 2017

11

1 reference

14 August 2017

2567-2576

1 reference

Animal models of idiosyncratic drug reactions

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

A fresh look at the mechanism of isoniazid-induced hepatotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Isoniazid-associated hepatitis in 114 patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Evaluation of isoniazid-associated hepatitis by immunological tests

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Isoniazid and Iproniazid: Activation of Metabolites to Toxic Intermediates in Man and Rat

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Involvement of T helper 17 cells in D-penicillamine-induced autoimmune disease in Brown Norway rats

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

The predictive value of the lymphocyte transformation test in isoniazid-associated hepatitis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Increased urinary excretion of toxic hydrazino metabolites of isoniazid by slow acetylators. Effect of a slow-release preparation of isoniazid

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Metabolism of isoniazid by activated leukocytes. Possible role in drug-induced lupus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Severe isoniazid-associated liver injuries among persons being treated for latent tuberculosis infection - United States, 2004-2008.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Evaluation of clinical and immunogenetic risk factors for the development of hepatotoxicity during antituberculosis treatment

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Advantages of glutamate dehydrogenase as a blood biomarker of acute hepatic injury in rats

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Unprecedented oxidation of a biologically active aroylhydrazone chelator catalysed by iron(III): serendipitous identification of diacylhydrazine ligands with high iron chelation efficacy

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501148

Role of hydrazine in the mechanism of isoniazid hepatotoxicity in rabbits

21 September 2018

1 reference

12 December 2020

Mitochondrial oxidative stress and permeability transition in isoniazid and rifampicin induced liver injury in mice

1 reference

12 December 2020

1 reference

12 December 2020

Isoniazid hepatoxicity: the relationship between covalent binding and metabolism in vivo

1 reference

12 December 2020

Is isoniazid-hepatotoxicity induced by the metabolite, hydrazine?

1 reference

12 December 2020

Pharmacokinetics of the toxic hydrazino metabolites formed from isoniazid in humans

1 reference

12 December 2020

Study of oxidative-stress in isoniazid-rifampicin induced hepatic injury in young rats

1 reference

12 December 2020

Identifiers

DOI

10.1021/TX300341R

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

23016703

1 reference