(Q36412050)

English

Glutamine substitution at alanine1649 in the S4-S5 cytoplasmic loop of domain 4 removes the voltage sensitivity of fast inactivation in the human heart sodium channel

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Glutamine substitution at alanine1649 in the S4-S5 cytoplasmic loop of domain 4 removes the voltage sensitivity of fast inactivation in the human heart sodium channel (English)

1 reference

Europe PubMed Central

14 August 2017

author name string

L Tang

1

1 reference

Europe PubMed Central

14 August 2017

N Chehab

2

1 reference

Europe PubMed Central

14 August 2017

S J Wieland

3

1 reference

Europe PubMed Central

14 August 2017

R G Kallen

4

1 reference

Europe PubMed Central

14 August 2017

publication date

1 May 1998

1 reference

Europe PubMed Central

14 August 2017

The Journal of General Physiology

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Europe PubMed Central

14 August 2017

111

1 reference

Europe PubMed Central

14 August 2017

5

1 reference

Europe PubMed Central

14 August 2017

639-652

1 reference

Europe PubMed Central

14 August 2017

The components of membrane conductance in the giant axon of Loligo

1 reference

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Role in fast inactivation of the IV/S4-S5 loop of the human muscle Na+ channel probed by cysteine mutagenesis

1 reference

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Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domains

1 reference

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Interaction between the sodium channel inactivation linker and domain III S4-S5.

1 reference

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Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment

1 reference

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Restoration of fast inactivation in an inactivation-defective human heart sodium channel by the cysteine modifying reagent benzyl-MTS: analysis of IFM-ICM mutation

1 reference

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Molecular analysis of the putative inactivation particle in the inactivation gate of brain type IIA Na+ channels

1 reference

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Voltage-dependent gating characteristics of the K+ channel KAT1 depend on the N and C termini

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Role of the S3-S4 linker in Shaker potassium channel activation

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A unique role for the S4 segment of domain 4 in the inactivation of sodium channels

1 reference

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Interaction between fast and slow inactivation in Skm1 sodium channels

1 reference

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N-type inactivation and the S4-S5 region of the Shaker K+ channel

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Role of an S4-S5 linker in sodium channel inactivation probed by mutagenesis and a peptide blocker

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Paramyotonia congenita: the R1448P Na+ channel mutation in adult human skeletal muscle

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A molecular link between activation and inactivation of sodium channels

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Structure, function and expression of voltage-dependent sodium channels

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S4 mutations alter gating currents of Shaker K channels

1 reference

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Molecular mechanism for an inherited cardiac arrhythmia

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The kinetics of voltage-gated ion channels

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Voltage gating of ion channels

1 reference

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

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Sodium channels and gating currents

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Currents related to movement of the gating particles of the sodium channels

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Molecular properties of voltage-sensitive sodium channels

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Gating of sodium and potassium channels

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Voltage-dependent gating of Shaker A-type potassium channels in Drosophila muscle

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Biophysical and molecular mechanisms of Shaker potassium channel inactivation

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A role for hydrophobic residues in the voltage-dependent gating of Shaker K+ channels

1 reference

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Voltage-sensing residues in the S4 region of a mammalian K+ channel

1 reference

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Hydrophobic substitution mutations in the S4 sequence alter voltage-dependent gating in Shaker K+ channels

1 reference

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A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel

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Molecular kinetics of voltage-dependent Na+ channels

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Atomic scale structure and functional models of voltage-gated potassium channels

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A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

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Removal of sodium channel inactivation in squid giant axons by n-bromoacetamide

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Molecular basis of charge movement in voltage-gated sodium channels

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Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation

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Effects of III-IV linker mutations on human heart Na+ channel inactivation gating

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Electrostatic interactions of S4 voltage sensor in Shaker K+ channel

1 reference

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Panning transfected cells for electrophysiological studies

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Alteration and restoration of K+ channel function by deletions at the N- and C-termini.

1 reference

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Changes in sodium channel gating produced by point mutations in a cytoplasmic linker

1 reference

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Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB.

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Putative receptor for the cytoplasmic inactivation gate in the Shaker K+ channel

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Arginine-specific reagents remove sodium channel inactivation

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Point mutations in IIS4 alter activation and inactivation of rat brain IIA Na channels in Xenopus oocyte macropatches.

1 reference

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Transmembrane movement of the shaker K+ channel S4.

1 reference

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Gating charge differences between two voltage-gated K+ channels are due to the specific charge content of their respective S4 regions.

1 reference

https://api.crossref.org/works/10.1085%2FJGP.111.5.639

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Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel.

1 reference

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A reinterpretation of mammalian sodium channel gating based on single channel recording

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Structural parts involved in activation and inactivation of the sodium channel

1 reference

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Sodium conductance activation without inactivation in pronase-perfused axons

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Identification of an intracellular peptide segment involved in sodium channel inactivation

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Evidence for voltage-dependent S4 movement in sodium channels

1 reference

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21 January 2018

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10.1085/JGP.111.5.639

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Europe PubMed Central

14 August 2017

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https://api.fatcat.wiki/v0/release/myndyhva4raz5ovsowtfadklfi

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Europe PubMed Central

14 August 2017

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Europe PubMed Central

14 August 2017

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