(Q36426768)

14 August 2017

1 reference

title

The PPARalpha-PGC-1alpha Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium (English)

1 reference

14 August 2017

Jennifer G Duncan

1

1 reference

14 August 2017

Brian N Finck

series ordinal

2

1 reference

14 August 2017

language of work or name

1 reference

1 January 2008

1 reference

14 August 2017

1 reference

14 August 2017

2008

1 reference

14 August 2017

253817

1 reference

Creative Commons Attribution 3.0 Unported

14 August 2017

start time

1 January 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Transcriptional regulation of metabolism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Adiposity of the heart, revisited

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Metabolic control through the PGC-1 family of transcription coactivators

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Thyroid hormone interacts with PPARalpha and PGC-1 during mitochondrial maturation in sheep heart

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Mitochondrial energy metabolism in heart failure: a question of balance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Transcriptional regulation and the role of diverse coactivators in animal cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Nuclear receptor signaling and cardiac energetics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Is the failing heart energy starved? On using chemical energy to support cardiac function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

"Energenetics" of heart failure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Regulation and role of the mitochondrial transcription factor in the diabetic rat heart

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Metabolic remodelling of the failing heart: the cardiac burn-out syndrome?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Energy metabolism in heart failure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Metabolic therapy in the treatment of ischaemic heart disease: the pharmacology of trimetazidine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

The use of partial fatty acid oxidation inhibitors for metabolic therapy of angina pectoris and heart failure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Nuclear activators and coactivators in mammalian mitochondrial biogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Reduced activity of mtTFA decreases the transcription in mitochondria isolated from diabetic rat heart

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Therapeutic potential of CPT I inhibitors: cardiac gene transcription as a target

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

A novel mouse model of lipotoxic cardiomyopathy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Lipotoxic heart disease in obese rats: implications for human obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Activation of PPARgamma coactivator-1 through transcription factor docking

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Myocardial utilization of carbohydrate and lipids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Triglycerides, cholesterol, and phospholipids in normal heart papillary muscle and in patients suffering from diabetes, cholelithiasis, hypertension, and coronary atheroma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

New type of cardiomyopathy associated with diabetic glomerulosclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

The diabetic heart: metabolic causes for the development of a cardiomyopathy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Protection against myocardial ischaemia/reperfusion injury by PPAR-alpha activation is related to production of nitric oxide and endothelin-1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Characterization of carnitine and fatty acid metabolism in the long-chain acyl-CoA dehydrogenase-deficient mouse

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Less extrahepatic induction of fatty acid beta-oxidation enzymes by PPAR alpha

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Regulation of energy substrate metabolism in the diabetic heart

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Myocardial high-energy phosphate and substrate metabolism in swine with moderate left ventricular hypertrophy

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

The WHO Multinational Study of Vascular Disease in Diabetes: 2. Macrovascular Disease Prevalence

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Effect of BM 17.0744, a PPARalpha ligand, on the metabolism of perfused hearts from control and diabetic mice

28 June 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

PPAR-alpha activation required for decreased glucose uptake and increased susceptibility to injury during ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Chronic activation of PPARalpha is detrimental to cardiac recovery after ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated wi

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

G-protein signaling participates in the development of diabetic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Myocardial carnitine palmitoyltransferase I expression and long-chain fatty acid oxidation in fetal and newborn lambs

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Hypoxia-induced switches of myosin heavy chain iso-gene expression in rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Postinfarction heart failure in rats is associated with upregulation of GLUT-1 and downregulation of genes of fatty acid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

The PPARalpha activator fenofibrate slows down the progression of the left ventricular dysfunction in porcine tachycardia-induced cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Overexpression of angiotensinogen in the myocardium induces downregulation of the fatty acid oxidation pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Effects of chronic activation of peroxisome proliferator-activated receptor-alpha or high-fat feeding in a rat infarct model of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Cardiac-specific overexpression of GLUT1 prevents the development of heart failure attributable to pressure overload in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Partial inhibition of fatty acid oxidation increases regional contractile power and efficiency during demand-induced ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Activation of peroxisome proliferator-activated receptor-alpha protects the heart from ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Very-long-chain acyl-coenzyme a dehydrogenase deficiency in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

Ligands of the peroxisome proliferator-activated receptor-PPAR-a reduce myocardial infarct size.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2225461

CD36 Deficiency Rescues Lipotoxic Cardiomyopathy

21 September 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F253817

Effects of Fenofibrate on Cardiac Remodeling in Aldosterone-Induced Hypertension

21 January 2018

1 reference

12 December 2020

Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy

1 reference

12 December 2020

Mitochondrial dysfunction observed in situ in cardiomyocytes of rats in experimental diabetes

1 reference

12 December 2020

Activation of peroxisome proliferator-activated receptor-alpha prevents glycogen synthase 3beta phosphorylation and inhibits cardiac hypertrophy

1 reference

12 December 2020

Altered expression of proteins of metabolic regulation during remodeling of the left ventricle after myocardial infarction

1 reference

12 December 2020

Fatty acid oxidation enzyme gene expression is downregulated in the failing heart

1 reference

12 December 2020

Altered glucose and fatty acid oxidation in hearts of the spontaneously hypertensive rat

1 reference

12 December 2020

Inhibition of PPAR-α activity in mice with cardiac-restricted expression of tumor necrosis factor: potential role of TGF-β/Smad3

1 reference

12 December 2020

Defective oxidative metabolism of heart mitochondria from genetically diabetic mice

1 reference

12 December 2020

Chronic activation of peroxisome proliferator-activated receptor-alpha with fenofibrate prevents alterations in cardiac metabolic phenotype without changing the onset of decompensation in pacing-induced heart failure

1 reference

12 December 2020

Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts

1 reference

12 December 2020

Diabetic cardiomyopathy

1 reference

12 December 2020

Partial fatty acid oxidation inhibitors: a potentially new class of drugs for heart failure

1 reference

12 December 2020

Inherited cardiomyopathies

1 reference

12 December 2020

Effects of moderate hypertension on cardiac function and metabolism in the rabbit

1 reference

12 December 2020

Attenuation of cardiac dysfunction by a PPAR-alpha agonist is associated with down-regulation of redox-regulated transcription factors

1 reference

12 December 2020

Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging

1 reference

12 December 2020

Cardiac high-energy phosphate metabolism in patients with aortic valve disease assessed by 31P-magnetic resonance spectroscopy

1 reference

12 December 2020

Perinatal changes in myocardial metabolism in lambs

1 reference

12 December 2020

Endogenous triacylglycerol metabolism in diabetic heart

1 reference

12 December 2020

Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity

1 reference

12 December 2020

Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice

1 reference

12 December 2020

Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy

1 reference

12 December 2020

Glycolysis and glucose oxidation during reperfusion of ischemic hearts from diabetic rats

1 reference

12 December 2020

Diabetic cardiomyopathy

1 reference

12 December 2020

Identifiers

DOI

10.1155/2008/253817

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

18288281

1 reference