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Human RNase L tunes gene expression by selectively destabilizing the microRNA-regulated transcriptome.
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PMC publication ID
4702973
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26668391%20AND%20SRC:MED&resulttype=core&format=json
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2 March 2020
title
Human RNase L tunes gene expression by selectively destabilizing the microRNA-regulated transcriptome
(English)
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PMC publication ID
4702973
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2 March 2020
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transcriptome
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microRNA
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Sneha Rath
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1
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4702973
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2 March 2020
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Jesse Donovan
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2
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2 March 2020
Gena Whitney
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2 March 2020
Alisha Chitrakar
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2 March 2020
Wei Wang
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5
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2 March 2020
Alexei Korennykh
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6
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publication date
14 December 2015
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2 March 2020
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Proceedings of the National Academy of Sciences of the United States of America
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2 March 2020
volume
112
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2 March 2020
issue
52
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2 March 2020
page(s)
15916-15921
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2 March 2020
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RNase L attenuates mitogen-stimulated gene expression via transcriptional and post-transcriptional mechanisms to limit the proliferative response
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Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response
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Innate immune messenger 2-5A tethers human RNase L into active high-order complexes
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Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by RNase L and tristetraprolin, and involvement of AU-rich elements.
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RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation
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Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis
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Endoribonuclease L (RNase L) regulates the myogenic and adipogenic potential of myogenic cells
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Viral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral response
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Small self-RNA generated by RNase L amplifies antiviral innate immunity
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A transcriptional signaling pathway in the IFN system mediated by 2'-5'-oligoadenylate activation of RNase L.
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30 September 2017
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
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30 September 2017
Involvement of microRNA in AU-rich element-mediated mRNA instability
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30 September 2017
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
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30 September 2017
RNase L mediates transient control of the interferon response through modulation of the double-stranded RNA-dependent protein kinase PKR.
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30 September 2017
The 2-5A/RNase L/RNase L inhibitor (RLI) [correction of (RNI)] pathway regulates mitochondrial mRNAs stability in interferon alpha-treated H9 cells
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30 September 2017
Structural basis for recognition of AU-rich element RNA by the HuD protein
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30 September 2017
The 2'-5' oligoadenylate/RNase L/RNase L inhibitor pathway regulates both MyoD mRNA stability and muscle cell differentiation
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30 September 2017
RNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response
1 reference
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reference URL
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30 September 2017
Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L
1 reference
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reference URL
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30 September 2017
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28 June 2018
RNase L downmodulation of the RNA-binding protein, HuR, and cellular growth
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28 June 2018
RNase-L regulates the stability of mitochondrial DNA-encoded mRNAs in mouse embryo fibroblasts
1 reference
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PubMed Central
reference URL
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28 June 2018
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1 reference
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PubMed Central
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21 September 2018
A census of human RNA-binding proteins
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21 January 2018
Interferon Action: RNA Cleavage Pattern of a (2′-5′)Oligoadenylate—Dependent Endonuclease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26668391
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.1513034112
1 reference
stated in
Europe PubMed Central
PMC publication ID
4702973
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26668391%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
ADS bibcode
2015PNAS..11215916R
0 references
PMC publication ID
4702973
1 reference
stated in
Europe PubMed Central
PMC publication ID
4702973
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26668391%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PubMed publication ID
26668391
1 reference
stated in
Europe PubMed Central
PMC publication ID
4702973
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26668391%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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