(Q36439183)

14 August 2017

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title

Mechanisms of drug-induced liver injury. (English)

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14 August 2017

Michael P Holt

1

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14 August 2017

Cynthia Ju

series ordinal

2

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14 August 2017

language of work or name

English

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publication date

3 February 2006

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14 August 2017

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14 August 2017

8

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14 August 2017

E48-54

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14 August 2017

1

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https://scigraph.springernature.com/pub.10.1208/aapsj080106

14 August 2017

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cites work

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Clinical perspectives on xenobiotic-induced hepatotoxicity

30 September 2017

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Drug-induced liver injury: what you need to know

30 September 2017

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Drug-induced hepatotoxicity.

30 September 2017

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Characterization of drug-specific T cells in lamotrigine hypersensitivity

30 September 2017

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Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States

30 September 2017

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Timing of new black box warnings and withdrawals for prescription medications

30 September 2017

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Immunology of the healthy liver: old questions and new insights

30 September 2017

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The liver as a site of T-cell apoptosis: graveyard, or killing field?

30 September 2017

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Innate and adaptive lymphoid cells in the human liver

30 September 2017

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The hepatic inflammatory response after acetaminophen overdose: role of neutrophils

30 September 2017

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Drug-induced liver diseases

30 September 2017

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Hepatotoxicity due to troglitazone: report of two cases and review of adverse events reported to the United States Food and Drug Administration

30 September 2017

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Bromfenac (Duract)-associated hepatic failure requiring liver transplantation

30 September 2017

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Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells

30 September 2017

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Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones

30 September 2017

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Lymphocyte responses and cytokines

30 September 2017

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Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase

30 September 2017

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Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

30 September 2017

1 reference

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Antibodies to the surface of halothane-altered rabbit hepatocytes in patients with severe halothane-associated hepatitis

28 June 2018

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Induction of immunological tolerance by porcine liver allografts.

28 June 2018

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Liver sinusoidal lining cells express class II major histocompatibility antigens but are poor stimulators of fresh allogeneic T lymphocytes.

28 June 2018

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Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity

21 September 2018

1 reference

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Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype, and cytokine profile of drug-specific T cell clones

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

A protective role for cyclooxygenase-2 in drug-induced liver injury in mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

Cultured NK1.1+ CD4+ T cells produce large amounts of IL-4 and IFN-gamma upon activation by anti-CD3 or CD1.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

Cytotoxic NK1.1 Ag+ alpha beta T cells with intermediate TCR induced in the liver of mice by IL-12.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

The human liver contains multiple populations of NK cells, T cells, and CD3+CD56+ natural T cells with distinct cytotoxic activities and Th1, Th2, and Th0 cytokine secretion patterns

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

Peripheral deletion of autoreactive CD8+ T cells in transgenic mice expressing H-2Kb in the liver

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751423

Inhibition of mitochondrial respiration in vivo is an early event in acetaminophen-induced hepatotoxicity

4 December 2018

1 reference

12 December 2020

Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition

1 reference

12 December 2020

Tienilic acid-induced autoimmune hepatitis: anti-liver and-kidney microsomal type 2 autoantibodies recognize a three-site conformational epitope on cytochrome P4502C9

1 reference

12 December 2020

Safety of newly approved drugs: implications for prescribing

1 reference

12 December 2020

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism

1 reference

12 December 2020

Induction of immune hyporesponsiveness after portal vein immunization with ovalbumin

1 reference

12 December 2020

Kupffer cell blockade inhibits induction of tolerance by the portal venous route

1 reference

12 December 2020

Role of neutrophils in hepatotoxicity induced by oral acetaminophen administration in rats

1 reference

12 December 2020

The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo

1 reference

12 December 2020

Hepatic Suppression of Sensitization to Antigen absorbed into the Portal System

1 reference

12 December 2020

Interactions of dihydralazine with cytochromes P4501A: a possible explanation for the appearance of anti-cytochrome P4501A2 autoantibodies

1 reference

12 December 2020

Acetaminophen-induced inhibition of hepatic mitochondrial respiration in mice

1 reference

12 December 2020

Histopathology of acetaminophen-induced liver changes: role of interleukin 1 alpha and tumor necrosis factor alpha

1 reference

12 December 2020

Evidence that donor spleen cells administered through the portal vein prolong the survival of cardiac allografts in rats

1 reference

12 December 2020

IL-18 accounts for both TNF-alpha- and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice

1 reference

12 December 2020

Abrogation of the induction of portal venous tolerance in a cardiac transplant model resulting from Kupffer cell inhibition by gadolinium

1 reference

12 December 2020

Prolongation of rat small bowel or renal allograft survival by pretransplant transfusion and/or by varying the route of allograft venous drainage

1 reference

12 December 2020

Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species

1 reference

12 December 2020

Kupffer cell blockade prevents induction of portal venous tolerance in rat cardiac allograft transplantation

1 reference

12 December 2020

Role of proinflammatory cytokines in acetaminophen hepatotoxicity

1 reference

12 December 2020

Immunomodulatory effects of the liver: deletion of activated CD4+ effector cells and suppression of IFN-gamma-producing cells after intravenous protein immunization

1 reference

12 December 2020

Drug-induced liver disease

1 reference

12 December 2020

Identifiers

DOI

10.1208/AAPSJ080106

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Dimensions Publication ID

14 August 2017

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14 August 2017

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