(Q36451029)

14 August 2017

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title

Mesoderm induction: from caps to chips (English)

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14 August 2017

David Kimelman

1

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14 August 2017

1 May 2006

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14 August 2017

Nature Reviews Genetics

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14 August 2017

7

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14 August 2017

360-372

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14 August 2017

5

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https://scigraph.springernature.com/pub.10.1038/nrg1837

14 August 2017

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Synergistic induction of mesoderm by FGF and TGF-beta and the identification of an mRNA coding for FGF in the early Xenopus embryo.

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Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos

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Organization of cardiac chamber progenitors in the zebrafish blastula

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The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

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Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning.

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A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta.

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The left-right coordinator: the role of Vg1 in organizing left-right axis formation.

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Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor

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The DVR-1 (Vg1) transcript of zebrafish is maternally supplied and distributed throughout the embryo.

21 January 2018

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Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos

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An interacting network of T-box genes directs gene expression and fate in the zebrafish mesoderm

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Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development.

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Repression of the vertebrate organizer by Wnt8 is mediated by Vent and Vox.

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Wnt/beta-catenin regulation of the Sp1-related transcription factor sp5l promotes tail development in zebrafish.

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Dorsal-ventral patterning and neural induction in Xenopus embryos

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Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos

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Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes

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The role of BMP signaling in outgrowth and patterning of the Xenopus tail bud.

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The molecular nature of the zebrafish tail organizer

21 January 2018

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Analysis of the developing Xenopus tail bud reveals separate phases of gene expression during determination and outgrowth.

21 January 2018

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Zebrafish admp is required to restrict the size of the organizer and to promote posterior and ventral development.

21 January 2018

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Cooperative action of ADMP- and BMP-mediated pathways in regulating cell fates in the zebrafish gastrula.

21 January 2018

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Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field

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Nuclear exclusion of Smad2 is a mechanism leading to loss of competence

21 January 2018

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Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

21 January 2018

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SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7.

21 January 2018

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Glypican 4 modulates FGF signalling and regulates dorsoventral forebrain patterning in Xenopus embryos

21 January 2018

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Fgf signaling is required for zebrafish tooth development

21 January 2018

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Transgenic zebrafish reveal stage-specific roles for Bmp signaling in ventral and posterior mesoderm development.

21 January 2018

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Reiterated Wnt signaling during zebrafish neural crest development

21 January 2018

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FGF signal interpretation is directed by Sprouty and Spred proteins during mesoderm formation

21 January 2018

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Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer.

21 January 2018

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Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1.

21 January 2018

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A hierarchy of gene expression accompanying induction of the primitive streak by Vg1 in the chick embryo

21 January 2018

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The hypoblast of the chick embryo positions the primitive streak by antagonizing nodal signaling

21 January 2018

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Determination of embryonic polarity in a regulative system: evidence for endogenous inhibitors acting sequentially during primitive streak formation in the chick embryo

21 January 2018

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Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3

21 January 2018

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Requirement for Wnt3 in vertebrate axis formation

21 January 2018

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Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo

21 January 2018

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Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks

21 January 2018

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Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development

21 January 2018

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Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

21 January 2018

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Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

21 January 2018

1 reference

Microarray-based identification of VegT targets in Xenopus

21 January 2018

1 reference

Screening of FGF target genes in Xenopus by microarray: temporal dissection of the signalling pathway using a chemical inhibitor

21 January 2018

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Tissue generation from amphibian animal caps

21 January 2018

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Long-term culture of Xenopus presumptive ectoderm in a nutrient-supplemented culture medium

21 January 2018

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21 January 2018

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Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional screen in Xenopus.

21 January 2018

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A genetic regulatory network for Xenopus mesendoderm formation.

21 January 2018

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Specificity and versatility in tgf-beta signaling through Smads

21 January 2018

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You Wnt some, you lose some: oncogenes in the Wnt signaling pathway

21 January 2018

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Functions and regulations of fibroblast growth factor signaling during embryonic development

21 January 2018

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The EGF-CFC gene family in vertebrate development.

21 January 2018

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A novel Cripto-related protein reveals an essential role for EGF-CFCs in Nodal signalling in Xenopus embryos.

21 January 2018

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EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1.

21 January 2018

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BMP antagonism by Spemann's organizer regulates rostral-caudal fate of mesoderm.

21 January 2018

1 reference

Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning

21 January 2018

1 reference

Signals from the Yolk Cell Induce Mesoderm, Neuroectoderm, the Trunk Organizer, and the Notochord in Zebrafish

21 January 2018

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The role of maternal VegT in establishing the primary germ layers in Xenopus embryos

21 January 2018

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eFGF regulates Xbra expression during Xenopus gastrulation.

31 March 2020

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The EGF-CFC protein one-eyed pinhead is essential for nodal signaling

31 March 2020

1 reference

Bmp signaling: turning a half into a whole

31 March 2020

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Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1837

1 reference

14 August 2017

1 reference

PubMed ID

16619051