(Q36459201)

14 August 2017

Monitoring Huntington's disease progression through preclinical and early stages (English)

1 reference

14 August 2017

0 references

Chris Tang

1

1 reference

PMCID

3519443

14 August 2017

Andrew Feigin

series ordinal

2

1 reference

14 August 2017

1 August 2012

1 reference

Neurodegenerative disease management

14 August 2017

1 reference

14 August 2017

2

1 reference

14 August 2017

4

1 reference

14 August 2017

421-435

1 reference

Reciprocal Benefits of Mass-Univariate and Multivariate Modeling in Brain Mapping: Applications to Event-Related Functional MRI, H(2) (15)O-, and FDG-PET

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Alterations in brain transition metals in Huntington disease: an evolving and intricate story

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Rate of change in early Huntington's disease: a clinicometric analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Complex relationships between cerebral blood flow and brain atrophy in early Huntington's disease.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Development of biomarkers for Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Magnetic resonance perfusion imaging of resting-state cerebral blood flow in preclinical Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Diffusion Tensor Imaging in Preclinical Huntington's Disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Longitudinal change in regional brain volumes in prodromal Huntington disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Seeking brain biomarkers for preventive therapy in Huntington disease.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Contrasting gray and white matter changes in preclinical Huntington disease: an MRI study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection".

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Abnormal motor cortex plasticity in premanifest and very early manifest Huntington disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Metabolic brain networks in neurodegenerative disorders: a functional imaging approach

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Motor abnormalities in premanifest persons with Huntington's disease: the PREDICT-HD study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Abnormal motor cortex excitability in preclinical and very early Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Brain-specific proteins decline in the cerebrospinal fluid of humans with Huntington disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Ten-year rate of longitudinal change in neurocognitive and motor function in prediagnosis Huntington disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Detection of Huntington's disease decades before diagnosis: the Predict-HD study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Thalamic metabolism and symptom onset in preclinical Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Dopaminergic signaling and striatal neurodegeneration in Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Functional imaging of cerebral blood flow and glucose metabolism in Parkinson's disease and Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Psychiatric disorders in preclinical Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Preclinical Huntington's disease: compensatory brain responses during learning

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

A new approach to spatial covariance modeling of functional brain imaging data: ordinal trend analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Progression of structural neuropathology in preclinical Huntington's disease: a tensor based morphometry study.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Using advances in neuroimaging to detect, understand, and monitor disease progression in Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Interrater agreement in the assessment of motor manifestations of Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

The thalamostriatal system: a highly specific network of the basal ganglia circuitry

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Topography of cerebral atrophy in early Huntington's disease: a voxel based morphometric MRI study.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Neuropsychiatric aspects of Huntington's disease.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Subtle changes among presymptomatic carriers of the Huntington's disease gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Physiology of hypokinetic and hyperkinetic movement disorders: model for dyskinesia.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Rate of functional decline in Huntington's disease. Huntington Study Group

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Huntington's disease progression. PET and clinical observations.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Clozapine versus placebo in Huntington's disease: a double blind randomised comparative study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

30 September 2017

Regional distribution and clinical correlates of white matter structural damage in Huntington disease: a tract-based spatial statistics study

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Diffusion tensor imaging in presymptomatic and early Huntington's disease: Selective white matter pathology and its relationship to clinical measures.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

fMRI biomarker of early neuronal dysfunction in presymptomatic Huntington's Disease.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

PET study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Neuropathological classification of Huntington's disease

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Huntington's disease in Venezuela: 7 years of follow-up on symptomatic and asymptomatic individuals

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

D2 receptors in Huntington's disease: positron emission tomography findings and clinical correlates

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Allocortical involvement in Huntington's disease

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Huntington's disease: neurological assessment of potential gene carriers presenting for predictive DNA testing

28 June 2018

1 reference

A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length.

21 January 2018

1 reference

Spectrum of gait impairments in presymptomatic and symptomatic Huntington's disease

21 January 2018

1 reference

Early Detection of Huntington Disease

21 January 2018

1 reference

Attention, inhibition, and proximity to clinical onset in preclinical mutation carriers for Huntington's disease.

21 January 2018

1 reference

Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation--a longitudinal follow-up study

21 January 2018

1 reference

Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study

21 January 2018

1 reference

Ethyl-EPA in Huntington disease: a double-blind, randomized, placebo-controlled trial

21 January 2018

1 reference

Thalamic atrophy in Huntington's disease co-varies with cognitive performance: a morphometric MRI analysis

21 January 2018

1 reference

Executive dysfunction in early stages of Huntington's disease is associated with striatal and insular atrophy: a neuropsychological and voxel-based morphometric study.

21 January 2018

1 reference

Hypothalamic involvement in Huntington's disease: an in vivo PET study

21 January 2018

1 reference

Diffusion-weighted imaging in Huntington's disease

21 January 2018

1 reference

Changes in striatal dopamine D2 receptor binding in pre-clinical Huntington's disease

21 January 2018

1 reference

Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II.

21 January 2018

1 reference

[11C]raclopride-PET studies of the Huntington's disease rate of progression: relevance of the trinucleotide repeat length

21 January 2018

1 reference

Striatal dopamine D2 receptors, metabolism, and volume in preclinical Huntington disease.

21 January 2018

1 reference

Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease

21 January 2018

1 reference

Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.

21 January 2018

1 reference

Extrastriatal dopamine D(2) receptor binding in Huntington's disease

21 January 2018

1 reference

Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease

21 January 2018

1 reference

Distribution of grey matter atrophy in Huntington's disease patients: a combined ROI-based and voxel-based morphometric study.

21 January 2018

1 reference

Brain structure in preclinical Huntington's disease.

21 January 2018

1 reference

Longitudinal analysis of regional grey matter loss in Huntington disease: effects of the length of the expanded CAG repeat.

21 January 2018

1 reference

Automated quantification of caudate atrophy by local registration of serial MRI: evaluation and application in Huntington's disease.

21 January 2018

1 reference

Distinct brain volume changes correlating with clinical stage, disease progression rate, mutation size, and age at onset prediction as early biomarkers of brain atrophy in Huntington's disease

21 January 2018

1 reference

Regional and progressive thinning of the cortical ribbon in Huntington's disease

21 January 2018

1 reference

The distribution of structural neuropathology in pre-clinical Huntington's disease

21 January 2018

1 reference

Regional cortical thinning in preclinical Huntington disease and its relationship to cognition

21 January 2018

1 reference

The progression of regional atrophy in premanifest and early Huntington's disease: a longitudinal voxel-based morphometry study

21 January 2018

1 reference

Diffusion-weighted versus volumetric imaging of the striatum in early symptomatic Huntington disease

21 January 2018

1 reference

Longitudinal diffusion tensor imaging in Huntington's Disease

21 January 2018

1 reference

Myelin breakdown and iron changes in Huntington's disease: pathogenesis and treatment implications

21 January 2018

1 reference

Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Metabolic network abnormalities in early Huntington's disease: an [(18)F]FDG PET study.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3519443

Unified Huntington's disease rating scale: Reliability and consistency

21 September 2018

1 reference

Clinical trials aimed at detecting neuroprotection in Parkinson's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23243467

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2217/NMT.12.34

1 reference

14 August 2017

1 reference

14 August 2017

1 reference

PMCID

3519443