(Q36462079)

14 August 2017

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title

Thorough QT/QTc not so thorough: removes torsadogenic predictors from the T-wave, incriminates safe drugs, and misses profibrillatory drugs (English)

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14 August 2017

Luc M Hondeghem

1

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14 August 2017

publication date

1 March 2006

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Journal of Cardiovascular Electrophysiology

14 August 2017

published in

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14 August 2017

volume

17

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14 August 2017

issue

3

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14 August 2017

page(s)

337-340

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Drug-induced QT dispersion: does it predict the risk of torsade de pointes?

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1540-8167.2006.00347.X

Drug-induced torsades de pointes and implications for drug development.

21 January 2018

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Drug-induced prolongation of the QT interval

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Refining detection of drug-induced proarrhythmia: QT interval and TRIaD.

21 January 2018

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Non-antiarrhythmic drugs prolonging the QT interval: considerable use in seven countries

21 January 2018

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Sample size, power calculations, and their implications for the cost of thorough studies of drug induced QT interval prolongation

21 January 2018

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21 January 2018

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QTc interval (cardiac repolarization): lengthening after meals.

21 January 2018

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Individual QT-R-R relationship: average stability over time does not rule out an individual residual variability: implication for the assessment of drug effect on the QT interval.

21 January 2018

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Prolonged cardiac repolarisation during spontaneous nocturnal hypoglycaemia in children and adolescents with type 1 diabetes

21 January 2018

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Problems of heart rate correction in assessment of drug-induced QT interval prolongation.

21 January 2018

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Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

21 January 2018

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Comparative efficacy and safety of oral mexiletine and quinidine in benign or potentially lethal ventricular arrhythmias

21 January 2018

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Mortality in the Survival With ORal D-sotalol (SWORD) trial: why did patients die?

21 January 2018

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Effects of long-term oral administration of amiodarone on the electromechanical performance of rabbit ventricular muscle

21 January 2018

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21 January 2018

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Chaos and the transition to ventricular fibrillation: a new approach to antiarrhythmic drug evaluation

21 January 2018

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Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs

21 January 2018

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Cellular basis for QT dispersion.

21 January 2018

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Transmembrane action potential heterogeneity in the canine isolated arterially perfused right atrium: effect of IKr and IKur/Ito block

21 January 2018

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Spatial heterogeneity of action potential alternans during global ischemia in the rabbit heart

21 January 2018

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Cardiac ventricular automaticity induced by current of injury

21 January 2018

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Drug induced QT prolongation and torsades de pointes

21 January 2018

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The utility of hERG and repolarization assays in evaluating delayed cardiac repolarization: influence of multi-channel block

21 January 2018

1 reference

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QT interval variability and spontaneous ventricular tachycardia or fibrillation in the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II patients

21 January 2018

1 reference

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Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1540-8167.2006.00347.X

Practical use of T wave morphology assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1540-8167.2006.00347.X

10.1111/J.1540-8167.2006.00347.X

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference