(Q36463071)

14 August 2017

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title

Mechanisms of disease: Genetic mechanisms of atrial fibrillation (English)

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14 August 2017

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Robert Roberts

1

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14 August 2017

1 May 2006

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Nature Clinical Practice Cardiovascular Medicine

14 August 2017

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14 August 2017

3

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14 August 2017

5

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14 August 2017

276-282

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Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs

14 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Basic mechanisms of atrial fibrillation--very new insights into very old ideas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Atrial electrophysiological remodeling caused by rapid atrial activation: underlying mechanisms and clinical relevance to atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Lifetime risk for development of atrial fibrillation: the Framingham Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

The Prognosis for Patients with Cerebrovascular Stroke and Transient Ischemic Attacks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Atrial fibrillation: a major contributor to stroke in the elderly. The Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Familial atrial fibrillation is a genetically heterogeneous disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

The natural history of lone atrial fibrillation. A population-based study over three decades

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Is atrial fibrillation a genetic disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Identification of a genetic locus for familial atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

KCNQ1 gain-of-function mutation in familial atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

A constitutively open potassium channel formed by KCNQ1 and KCNE3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

KCNE4 is an inhibitory subunit to the KCNQ1 channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Mutations in the long QT gene, KCNQ1, are an uncommon cause of atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Transgenic upregulation of IK1 in the mouse heart leads to multiple abnormalities of cardiac excitability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Molecular basis of downregulation of G-protein-coupled inward rectifying K(+) current (I(K,ACh) in chronic human atrial fibrillation: decrease in GIRK4 mRNA correlates with reduced I(K,ACh) and muscarinic receptor-mediated shortening of action poten

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Human inward rectifier potassium channels in chronic and postoperative atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Electrophysiological remodeling in human atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Short QT syndrome and atrial fibrillation caused by mutation in KCNH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Genome-wide linkage scan identifies a novel genetic locus on chromosome 5p13 for neonatal atrial fibrillation associated with sudden death and variable cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

The Sequence of the Human Genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Unraveling monogenic channelopathies and their implications for complex polygenic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Expression of multiple KCNE genes in human heart may enable variable modulation of I(Ks).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

The molecular genetic basis for hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Identification and characterization of a novel gene (C4orf5) located on human chromosome 4q with specific expression in cardiac and skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Identification of a gene responsible for familial Wolff-Parkinson-White syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Renin-angiotensin system gene polymorphisms and atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Association of the human minK gene 38G allele with atrial fibrillation: evidence of possible genetic control on the pathogenesis of atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Crystal structure of the potassium channel KirBac1.1 in the closed state

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

7 January 2021

Clinical spectrum of the sick sinus syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

7 January 2021

Outward K+ current densities and Kv1.5 expression are reduced in chronic human atrial fibrillation

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

7 January 2021

Idiopathic short QT interval: a new clinical syndrome?

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

7 January 2021

Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

7 January 2021

Association of human connexin40 gene polymorphisms with atrial vulnerability as a risk factor for idiopathic atrial fibrillation

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0509

7 January 2021

Identifiers

DOI

10.1038/NCPCARDIO0509

1 reference

14 August 2017

1 reference

PubMed ID

16645668