(Q36463113)

14 August 2017

1 reference

title

Gastric H,K-ATPase as a drug target (English)

1 reference

14 August 2017

Jai Moo Shin

1

1 reference

PubMed ID

16645899

14 August 2017

George Sachs

series ordinal

2

1 reference

14 August 2017

28 April 2006

1 reference

Digestive Diseases and Sciences

14 August 2017

1 reference

14 August 2017

51

1 reference

14 August 2017

5

1 reference

14 August 2017

823-833

1 reference

https://scigraph.springernature.com/pub.10.1007/s10620-005-9042-8

14 August 2017

0 references

cites work

cDNA cloning and membrane topology of the rabbit gastric H+/K+-ATPase α-subunit

1 reference

https://api.crossref.org/works/10.1007%2FS10620-005-9042-8

Mechanism of inhibition of H+, K(+)-ATPase by sodium 2-[[4-(3- methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]-1H-benzimidazole (E3810)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-005-9042-8

Continuing development of acid pump inhibitors: site of action of pantoprazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-005-9042-8

Comparative pharmacokinetic/pharmacodynamic analysis of proton pump inhibitors omeprazole, lansoprazole and pantoprazole, in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-005-9042-8

SCH 28080 is a lumenally acting, K+-site inhibitor of the gastric (H+ + K+)-ATPase

21 January 2018

1 reference

12 December 2020

Identification of a region of the H,K-ATPase alpha subunit associated with the beta subunit.

1 reference

12 December 2020

Regions of association between the alpha and the beta subunit of the gastric H,K-ATPase.

1 reference

12 December 2020

Molecular cloning and structural analysis of canine gastric H+,K(+)-ATPase

1 reference

12 December 2020

Mutational analysis of the K+-competitive inhibitor site of gastric H,K-ATPase.

1 reference

12 December 2020

Inhibitor and ion binding sites on the gastric H,K-ATPase

1 reference

12 December 2020

The continuing development of gastric acid pump inhibitors

1 reference

12 December 2020

Differences in pH-dependent activation rates of substituted benzimidazoles and biological in vitro correlates

1 reference

12 December 2020

Turnover of the gastric H+,K(+)-adenosine triphosphatase alpha subunit and its effect on inhibition of rat gastric acid secretion

1 reference

12 December 2020

The H,K-ATPase beta subunit as a model to study the role of N-glycosylation in membrane trafficking and apical sorting

1 reference

12 December 2020

Isolation and characterization of a cDNA encoding the putative distal colon H+,K(+)-ATPase. Similarity of deduced amino acid sequence to gastric H+,K(+)-ATPase and Na+,K(+)-ATPase and mRNA expression in distal colon, kidney, and uterus

1 reference

12 December 2020

Dimerization of the gastric H+, K(+)-ATPase

1 reference

12 December 2020

Structural changes in the calcium pump accompanying the dissociation of calcium

1 reference

12 December 2020

Sites of reaction of the gastric H,K-ATPase with extracytoplasmic thiol reagents.

1 reference

12 December 2020

Location of the carbohydrates present in the HK-ATPase vesicles isolated from hog gastric mucosa

1 reference

12 December 2020

1 reference

12 December 2020

Characterization of a beta subunit of the gastric H+/K(+)-transporting ATPase

1 reference

12 December 2020

2-[[(4-Amino-2-pyridyl)methyl]sulfinyl]benzimidazole H+/K+-ATPase inhibitors. The relationship between pyridine basicity, stability, and activity

1 reference

12 December 2020

A nonelectrogenic H+ pump in plasma membranes of hog stomach

1 reference

12 December 2020

A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole

1 reference

12 December 2020

The specificity of omeprazole as an (H+ + K+)-ATPase inhibitor depends upon the means of its activation

1 reference

12 December 2020

Inhibition of (H+ + K+)-ATPase by omeprazole in isolated gastric vesicles requires proton transport

1 reference

12 December 2020

Kinetic properties of the KCl transport at the secreting apical membrane of the oxyntic cell

1 reference

12 December 2020

Crystal structures of Ca2+-ATPase in various physiological states.

1 reference

12 December 2020

Molecular cloning of the rat stomach (H+ + K+)-ATPase

1 reference

12 December 2020

Gastric adenosine triphosphatases: a review of their possible role in HCl secretion

1 reference

12 December 2020

SCH28080, a K+-competitive inhibitor of the gastric H,K-ATPase, binds near the M5-6 luminal loop, preventing K+ access to the ion binding domain

1 reference

12 December 2020

Ca2+ -ATPase structure in the E1 and E2 conformations: mechanism, helix-helix and helix-lipid interactions

1 reference

12 December 2020

Quantitative ultrastructural studies on gastric parietal cells

1 reference

12 December 2020

Localization of omeprazole and metabolites in the mouse

1 reference

12 December 2020

Structure and mechanism of Na,K-ATPase: functional sites and their interactions

1 reference

12 December 2020

Molecular modeling of SCH28080 binding to the gastric H,K-ATPase and MgATP interactions with SERCA- and Na,K-ATPases

1 reference

12 December 2020

Membrane topology and omeprazole labeling of the gastric H+,K(+)-adenosinetriphosphatase

1 reference

12 December 2020

1 reference

12 December 2020

Chemistry of covalent inhibition of the gastric (H+, K+)-ATPase by proton pump inhibitors

1 reference

12 December 2020

(H+, K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 4. A novel series of dimethoxypyridyl-substituted inhibitors with enhanced selectivity. The selection of pantoprazole as a clinical candidate

1 reference

12 December 2020

Evidence for acid-induced transformation of omeprazole into an active inhibitor of (H+ + K+)-ATPase within the parietal cell

1 reference

12 December 2020

The mechanism of action of the gastric acid secretion inhibitor omeprazole

1 reference

12 December 2020

The site of action of pantoprazole in the gastric H+/K(+)-ATPase

1 reference

12 December 2020

Characterization and development of cimetidine as a histamine H2-receptor antagonist

1 reference

12 December 2020

Restoration of acid secretion following treatment with proton pump inhibitors

1 reference

12 December 2020

Modeling of the inhibitory interaction of phospholamban with the Ca2+ ATPase.

1 reference

12 December 2020

Reversal of antisecretory activity of omeprazole by sulfhydryl compounds in isolated rabbit gastric glands

1 reference

12 December 2020

General pharmacology of IY-81149, a new proton pump inhibitor

1 reference

12 December 2020

Effects of antisecretory agents on parietal cell structure and H/K-ATPase levels in rabbit gastric mucosa in vivo

1 reference

12 December 2020

Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+) ATPase

1 reference

12 December 2020

Differentiation among inhibitory actions of omeprazole, cimetidine, and SCN- on gastric acid secretion

1 reference

12 December 2020

Possible mechanism for the inhibition of gastric (H+ + K+)-adenosine triphosphatase by the proton pump inhibitor AG-1749.

1 reference

12 December 2020

Structural studies on H+,K+-ATPase: determination of the NH2-terminal amino acid sequence and immunological cross-reactivity with Na+,K+-ATPase

1 reference

12 December 2020

The 60- to 90-kDa parietal cell autoantigen associated with autoimmune gastritis is a beta subunit of the gastric H+/K(+)-ATPase (proton pump).

1 reference

12 December 2020

Inactivation of H+,K+-ATPase by a K+-competitive photoaffinity inhibitor

1 reference

12 December 2020

10.1007/S10620-005-9042-8

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16645899