(Q36466223)

14 August 2017

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title

Translating the concept of suppressor/regulatory T cells to clinical applications (English)

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14 August 2017

Alessandra Franco

1

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14 August 2017

Salvatore Albani

series ordinal

2

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14 August 2017

publication date

1 January 2006

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International Reviews of Immunology

14 August 2017

published in

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14 August 2017

volume

25

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14 August 2017

issue

1-2

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14 August 2017

page(s)

27-47

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An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

14 August 2017

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Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro.

21 January 2018

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Selecting and maintaining a diverse T-cell repertoire

21 January 2018

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The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation

21 January 2018

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Ligands for the T-cell receptor: hard times for avidity models

21 January 2018

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Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

21 January 2018

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Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

21 January 2018

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Making the T cell receptor go the distance: a topological view of T cell activation

21 January 2018

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The structure and ligand interactions of CD2: implications for T-cell function

21 January 2018

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Antigen analogs/MHC complexes as specific T cell receptor antagonists

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

The role of T-cell receptor dimerization in T-cell activation.

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

21 January 2018

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Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

The minimal number of class II MHC-antigen complexes needed for T cell activation

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

The immunological synapse: a molecular machine controlling T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

Antigen decoding by T lymphocytes: from synapses to fate determination

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

Tolerance, danger, and the extended family

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

An integrated view of suppressor T cell subsets in immunoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Regulatory T cells and autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Feedback induction of suppressor T-cell activity

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions.

21 January 2018

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https://api.crossref.org/works/10.1080%2F08830180500544506

Role of CD8+ T cells in murine experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Murine CD8+ T cells that specifically delete autologous CD4+ T cells expressing V beta 8 TCR: a role of the Qa-1 molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Regulatory CD8+ T cells fine-tune the myelin basic protein-reactive T cell receptor V beta repertoire during experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The Qa-1 antigenic system. Relation of Qa-1 phenotypes to lymphocyte sets, mitogen responses, and immune functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Immunoregulatory circuits among T-cell sets. Identification of a subpopulation of T-helper cells that induces feedback inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Analysis of regulatory CD8 T cells in Qa-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The specific regulation of immune responses by CD8+ T cells restricted by the MHC class Ib molecule, Qa-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Suppression of autoimmune disease after vaccination with autoreactive T cells that express Qa-1 peptide complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Neuropilin-1: a surface marker of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

In vivo instruction of suppressor commitment in naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Regulatory T cells in spontaneous autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

CD4(+) regulatory T cells in autoimmunity and allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

A function for interleukin 2 in Foxp3-expressing regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Nature of polymorphism in HLA-A, -B, and -C molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

T cell receptor antagonists and partial agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

T cell receptor antagonist peptides are highly effective inhibitors of experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The dendritic cell system and its role in immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Immunobiology of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Regulation of T cell immunity by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Dendritic cells: regulators of alloimmunity and opportunities for tolerance induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The ups and downs of T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Tolerogenic dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

T-cell co-stimulation through B7RP-1 and ICOS

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

ICOS is essential for effective T-helper-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The B7/CD28 costimulatory family in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

CD28 affects the earliest signaling events generated by TCR engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

CTLA-4-Ig regulates tryptophan catabolism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Modulation of tryptophan catabolism by regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

License to heal: bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

21 January 2018

The B7 family revisited

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The TNF and TNF receptor superfamilies: integrating mammalian biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

TNF/TNFR family members in costimulation of T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Antigen presentation to naive CD4 T cells in the lymph node.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Immunotherapeutic approaches in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

A family of inhibitory and activating Ig-like receptors that modulate function of lymphoid and myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Immune inhibitory receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The LILR family: modulators of innate and adaptive immune pathways in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Dendritic cells: emerging pharmacological targets of immunosuppressive drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Suppression of acute experimental allergic encephalomyelitis with a small molecule inhibitor of alpha4 integrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Heat shock proteins in juvenile idiopathic arthritis: keys for understanding remitting arthritis and candidate antigens for immune therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Heat-shock proteins induce T-cell regulation of chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Positive selection in autoimmunity: Abnormal immune responses to a bacterial dnaJ antigenic determinant in patients with early rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Immune responses to the Escherichia coli dnaJ heat shock protein in juvenile rheumatoid arthritis and their correlation with disease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

A multistep molecular mimicry hypothesis for the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Autoreactivity to human heat-shock protein 60 predicts disease remission in oligoarticular juvenile rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Juvenile chronic arthritis: T cell reactivity to human HSP60 in patients with a favorable course of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Heat shock proteins as regulators of the immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis-associated and nonassociated HLA-DR4 alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Bacterial vaccines for the treatment of multiple sclerosis and other autoimmune disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Myelin-specific CD8 T cells in the pathogenesis of experimental allergic encephalitis and multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Genetic bias in immune responses to a cassette shared by different microorganisms in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The spontaneous remission of juvenile idiopathic arthritis is characterized by CD30+ T cells directed to human heat-shock protein 60 capable of producing the regulatory cytokine interleukin-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The role of immune tolerance in preventing and treating arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

T cell repertoire formation and molecular mimicry in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Therapy with cultured T cells: principles revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Identifying strategies for immune intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

MHC-restricted depletion of human myelin basic protein-reactive T cells by T cell vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Homeostatic control of immunity by TCR peptide-specific Tregs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The use of a non-depleting anti-CD4 monoclonal antibody to re-establish tolerance to beta cells in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Induction of tolerance in peripheral T cells with monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Simultaneous blockade of co-stimulatory signals, CD28 and ICOS, induced a stable tolerance in rat heart transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Isolation and characterization of antigen-la complexes involved in T cell recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

From TCR Engagement to T Cell Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Binding of immunogenic peptides to Ia histocompatibility molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500544506

10.1080/08830180500544506

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference