(Q36468012)

14 August 2017

Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina (English)

1 reference

Delta 4-desaturase, sphingolipid 1

14 August 2017

1 reference

1 reference

retinol isomerase activity

GOA release 2020-03-11

1 reference

Delta(4)-desaturase, sphingolipid 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Joanna J Kaylor

1

1 reference

14 August 2017

Quan Yuan

2

1 reference

14 August 2017

Jeremy Cook

3

1 reference

14 August 2017

Shanta Sarfare

4

1 reference

14 August 2017

Jacob Makshanoff

5

1 reference

14 August 2017

Anh Miu

6

1 reference

14 August 2017

Anita Kim

7

1 reference

14 August 2017

Paul Kim

8

1 reference

14 August 2017

Samer Habib

9

1 reference

14 August 2017

C Nathaniel Roybal

10

1 reference

14 August 2017

Tongzhou Xu

11

1 reference

14 August 2017

Steven Nusinowitz

12

1 reference

14 August 2017

Gabriel H Travis

13

1 reference

14 August 2017

11 November 2012

1 reference

14 August 2017

Nature Chemical Biology

1 reference

14 August 2017

9

1 reference

14 August 2017

1

1 reference

14 August 2017

30-36

1 reference

https://scigraph.springernature.com/pub.10.1038/nchembio.1114

14 August 2017

0 references

cites work

Identification of dihydroceramide desaturase as a direct in vitro target for fenretinide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Regulation of mammalian desaturases by myristic acid: N-terminal myristoylation and other modulations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

RPE65, visual cycle retinol isomerase, is not inherently 11-cis-specific: support for a carbocation mechanism of retinol isomerization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

The 11-cis-retinol dehydrogenase activity of RDH10 and its interaction with visual cycle proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Release of 11-cis-retinal from cellular retinaldehyde-binding protein by acidic lipids.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Temporal response properties of the primary and secondary rod-signaling pathways in normal and Gnat2 mutant mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-Based Retinal Diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

RPE65 is the isomerohydrolase in the retinoid visual cycle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Breaking the covalent bond--a pigment property that contributes to desensitization in cones.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Downregulation of cone-specific gene expression and degeneration of cone photoreceptors in the Rpe65-/- mouse at early ages

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Identification of RDH10, an All-trans Retinol Dehydrogenase, in Retinal Muller Cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Synthesis of cyclopropene analogues of ceramide and their effect on dihydroceramide desaturase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Isorhodopsin rather than rhodopsin mediates rod function in RPE65 knock-out mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

The thermal stability of rhodopsin and opsin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Disease-causing mutations in the cellular retinaldehyde binding protein tighten and abolish ligand interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Isomerization and oxidation of vitamin a in cone-dominant retinas: a novel pathway for visual-pigment regeneration in daylight

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Further characterization of rat dihydroceramide desaturase: tissue distribution, subcellular localization, and substrate specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Eight histidine residues are catalytically essential in a membrane-associated iron enzyme, stearoyl-CoA desaturase, and are conserved in alkane hydroxylase and xylene monooxygenase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

The photocurrent, noise and spectral sensitivity of rods of the monkey Macaca fascicularis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Immunocytochemical localization of two retinoid-binding proteins in vertebrate retina

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Retinoid requirements for recovery of sensitivity after visual-pigment bleaching in isolated photoreceptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Molecular mechanisms in visual pigment regeneration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Isorhodopsin II: artificial photosensitive pigment formed from 9,13-dicis retinal

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

An alternative pathway mediates the mouse and human cone visual cycle.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Evidence for two retinoid cycles in the cone-dominated chicken eye

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Glucose metabolism in photoreceptor outer segments. Its role in phototransduction and in NADPH-requiring reactions

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Recovery of cone receptor activity in the frog's isolated retina

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Muller cells of chicken retina synthesize 11-cis-retinol

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Retinal disease in Rpe65-deficient mice: comparison to human leber congenital amaurosis due to RPE65 mutations

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

N-Myristoylation targets dihydroceramide Delta4-desaturase 1 to mitochondria: partial involvement in the apoptotic effect of myristic acid.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Intra-retinal visual cycle required for rapid and complete cone dark adaptation.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Retinoid cycles in the cone-dominated chicken retina

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Correlation of regenerable opsin with rod ERG signal in Rpe65-/- mice during development and aging

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Dihydroceramide delta(4) desaturase initiates substrate oxidation at C-4.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Myristic acid increases the activity of dihydroceramide Δ4-desaturase 1 through its N-terminal myristoylation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522777

Rods and cones in the mouse retina. I. Structural analysis using light and electron microscopy

4 December 2018

1 reference

12 December 2020

The topographical distribution of rods and cones in the adult chicken retina

1 reference

12 December 2020

Localization of retinoid-binding proteins in developing rat retina

1 reference

12 December 2020

Cone pigment regeneration in the isolated frog retina

1 reference

12 December 2020

Photochemistry and stereoselectivity of cellular retinaldehyde-binding protein from bovine retina

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.1114

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

23143414

1 reference