(Q36468876)

14 August 2017

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title

Targeting the epidermal growth factor receptor in colorectal cancer: advances and controversies (English)

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14 August 2017

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Antoine Italiano

1

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14 August 2017

3 May 2006

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14 August 2017

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14 August 2017

70

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14 August 2017

3

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14 August 2017

161-167

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Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group

14 August 2017

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Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.

21 January 2018

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21 January 2018

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Pharmacodynamic studies with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839.

21 January 2018

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Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

21 January 2018

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Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.

21 January 2018

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Epidermal growth factor receptor levels are lower in carcinomatous than in normal colorectal tissue

21 January 2018

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Evaluation of the epidermal growth factor receptor (EGFR) in colorectal tumours and lymph node metastases

21 January 2018

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Impact of EGFR expression on colorectal cancer patient prognosis and survival

21 January 2018

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The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification

21 January 2018

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Epidermal growth factor receptors: critical mediators of multiple receptor pathways

21 January 2018

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Untangling the ErbB signalling network

21 January 2018

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Anticancer therapy targeting the erbB family of receptor tyrosine kinases

21 January 2018

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The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis

21 January 2018

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Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy

21 January 2018

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The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton

21 January 2018

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The epidermal growth factor receptor and its inhibition in cancer therapy

21 January 2018

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EGF receptor in neoplasia and metastasis

21 January 2018

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Epidermal growth factor receptor, c-MET, beta-catenin, and p53 expression as prognostic indicators in stage II colon cancer: a tissue microarray study

21 January 2018

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Assessing epidermal growth factor receptor expression in tumours: what is the value of current test methods?

21 January 2018

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Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.

21 January 2018

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Epidermal growth factor receptor (EGFR) status in primary colorectal tumors does not correlate with EGFR expression in related metastatic sites: implications for treatment with EGFR-targeted monoclonal antibodies.

21 January 2018

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Epidermal growth factor receptor (EGFR) status in primary colorectal tumors correlates with EGFR expression in related metastatic sites: biological and clinical implications.

21 January 2018

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Immunohistochemical detection of EGFR in paraffin-embedded tumor tissues: variation in staining intensity due to choice of fixative and storage time of tissue sections

21 January 2018

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Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

21 January 2018

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Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis.

21 January 2018

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A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover

21 January 2018

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Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors

21 January 2018

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High-affinity epidermal growth factor binding is specifically reduced by a monoclonal antibody, and appears necessary for early responses

21 January 2018

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Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor

21 January 2018

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The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function

21 January 2018

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EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000093092

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14 August 2017

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PubMed ID

16675911