(Q36470761)

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Hypophosphorylation of ribosomal protein S6 is a molecular mechanism underlying ischemic tolerance induced by either hibernation or preconditioning

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24 February 2020

Hypophosphorylation of ribosomal protein S6 is a molecular mechanism underlying ischemic tolerance induced by either hibernation or preconditioning (English)

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24 February 2020

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Joshua D. Bernstock

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24 February 2020

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Shin-ichi Miyake

1

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24 February 2020

Hideaki Wakita

2

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24 February 2020

Paola Castri

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24 February 2020

Christl Ruetzler

5

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24 February 2020

Junko Miyake

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24 February 2020

Yang-Ja Lee

7

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24 February 2020

John M Hallenbeck

8

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24 February 2020

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22 October 2015

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24 February 2020

Journal of Neurochemistry

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24 February 2020

135

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24 February 2020

5

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24 February 2020

943-957

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24 February 2020

Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance

1 reference

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30 September 2017

PF-4708671 activates AMPK independently of p70S6K1 inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

D-Glucosamine supplementation extends life span of nematodes and of ageing mice

1 reference

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30 September 2017

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

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30 September 2017

Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1).

1 reference

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30 September 2017

Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).

1 reference

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30 September 2017

SUMOylation participates in induction of ischemic tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Physiological roles of ribosomal protein S6: one of its kind

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Protein translation, 2007.

1 reference

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30 September 2017

Protein SUMOylation is massively increased in hibernation torpor and is critical for the cytoprotection provided by ischemic preconditioning and hypothermia in SHSY5Y cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Natural hypometabolism during hibernation and daily torpor in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Mammalian hibernation. Transcriptional and translational controls.

1 reference

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30 September 2017

Mammalian Hibernation: Cellular and Molecular Responses to Depressed Metabolism and Low Temperature

1 reference

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30 September 2017

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

1 reference

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30 September 2017

Ribosomal S6 kinase signaling and the control of translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Ischemic preconditioning and brain tolerance: temporal histological and functional outcomes, protein synthesis requirement, and interleukin-1 receptor antagonist and early gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Generation of a mutant form of protein synthesis initiation factor eIF-2 lacking the site of phosphorylation by eIF-2 kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Reversible middle cerebral artery occlusion without craniectomy in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Translational dynamics. Interactions between the translational factors, tRNA and ribosomes during eukaryotic protein synthesis

1 reference

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30 September 2017

Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs

1 reference

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30 September 2017

Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

30 September 2017

Local cerebral blood flow during hibernation, a model of natural tolerance to "cerebral ischemia".

1 reference

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28 June 2018

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

28 June 2018

Differential kinetics of changes in the state of phosphorylation of ribosomal protein S6 and in the rate of protein synthesis in MPC 11 cells during tonicity shifts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

28 June 2018

Group I metabotropic glutamate receptors activate the p70S6 kinase via both mammalian target of rapamycin (mTOR) and extracellular signal-regulated kinase (ERK 1/2) signaling pathways in rat striatal and hippocampal synaptoneurosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

21 September 2018

Glutamatergic regulation of the p70S6 kinase in primary mouse neurons

1 reference

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21 September 2018

MAPKs are differentially modulated in arctic ground squirrels during hibernation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

21 September 2018

Akt phosphorylation and kinase activity are down-regulated during hibernation in the 13-lined ground squirrel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

21 September 2018

Cycloheximide reduces infarct volume when administered up to 6 h after mild focal ischemia in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

21 September 2018

Mechanisms for increased levels of phosphorylation of elongation factor-2 during hibernation in ground squirrels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

21 September 2018

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

1 reference

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21 September 2018

Cerebrovascular hemodynamics and ischemic tolerance: lipopolysaccharide-induced resistance to focal cerebral ischemia is not due to changes in severity of the initial ischemic insult, but is associated with preservation of microvascular perfusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

21 September 2018

Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

21 September 2018

Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies.

1 reference

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21 September 2018

Lipopolysaccharide pre-treatment induces resistance against subsequent focal cerebral ischemic damage in spontaneously hypertensive rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715778

21 September 2018

Identification of the 40 S ribosomal protein S6 phosphorylation sites induced by cycloheximide

1 reference

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21 September 2018

A semiautomated method for measuring brain infarct volume.

1 reference

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21 September 2018

FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

1 reference

https://api.crossref.org/works/10.1111%2FJNC.13368

21 January 2018

Ischemic tolerance in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/26375300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-glucosamine inhibits proliferation of human cancer cells through inhibition of p70S6K

1 reference

https://pubmed.ncbi.nlm.nih.gov/26375300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hibernation and longevity in the Turkish hamster Mesocricetus brandti

1 reference

https://pubmed.ncbi.nlm.nih.gov/26375300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/JNC.13368

1 reference

Europe PubMed Central

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24 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26375300%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

Europe PubMed Central

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24 February 2020

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