(Q36476880)

14 August 2017

1 reference

title

Therapeutic concepts for hypoxic pulmonary vasoconstriction involving ion regulation and the smooth muscle contractile apparatus (English)

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14 August 2017

0 references

1 reference

Eric D Morrell

1

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14 August 2017

Ben M Tsai

2

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14 August 2017

Paul R Crisostomo

3

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14 August 2017

Meijing Wang

4

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14 August 2017

Troy A Markel

5

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14 August 2017

Keith D Lillemoe

6

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14 August 2017

Daniel R Meldrum

7

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14 August 2017

publication date

11 May 2006

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Journal of Molecular and Cellular Cardiology

14 August 2017

published in

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14 August 2017

volume

40

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14 August 2017

issue

6

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14 August 2017

page(s)

751-760

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Response of small pulmonary arteries to unilobar hypoxia and hypercapnia

14 August 2017

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7 January 2021

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7 January 2021

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N-acetylcysteine inhibits hypoxic pulmonary hypertension most effectively in the initial phase of chronic hypoxia

7 January 2021

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Antioxidants attenuate chronic hypoxic pulmonary hypertension

7 January 2021

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Hypoxic constriction and reactive oxygen species in porcine distal pulmonary arteries

7 January 2021

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Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing

7 January 2021

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Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes

7 January 2021

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Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia

7 January 2021

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Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes

7 January 2021

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Subacute hypoxia decreases voltage-activated potassium channel expression and function in pulmonary artery myocytes

7 January 2021

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Chronic hypoxia inhibits Kv channel gene expression in rat distal pulmonary artery

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells

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7 January 2021

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Chronic hypoxia decreases K(V) channel expression and function in pulmonary artery myocytes

7 January 2021

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Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction

7 January 2021

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Treatment of lactic acidosis with dichloroacetate

7 January 2021

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A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults. The Dichloroacetate-Lactic Acidosis Study Group

7 January 2021

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Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

Ion channels in pulmonary arterial hypertension

7 January 2021

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Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis

7 January 2021

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The pharmacology of dichloroacetate

7 January 2021

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Physiological roles and properties of potassium channels in arterial smooth muscle

7 January 2021

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Effects of iptakalim hydrochloride, a novel KATP channel opener, on pulmonary vascular remodeling in hypoxic rats

7 January 2021

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JTV-506, a new K(ATP) channel opener, relaxes pulmonary artery isolated from monocrotaline-treated pulmonary hypertensive rats

7 January 2021

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Regulation of arterial tone by activation of calcium-dependent potassium channels

7 January 2021

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Hypoxia increases the activity of Ca(2+)-sensitive K+ channels in cat cerebral arterial muscle cell membranes

7 January 2021

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Effect of chronic hypoxia on K+ channels: regulation in human pulmonary vascular smooth muscle cells

7 January 2021

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Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension

7 January 2021

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Dehydroepiandrosterone sulphate reduces chronic hypoxic pulmonary hypertension in rats

7 January 2021

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Dehydroepiandrosterone replacement in women with adrenal insufficiency.

7 January 2021

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Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue

7 January 2021

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Dehydroepiandrosterone inhibits human platelet aggregation in vitro and in vivo.

7 January 2021

1 reference

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Effects of levosimendan, a novel inotropic calcium-sensitizing drug, in experimental septic shock.

7 January 2021

1 reference

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End-stage heart failure with pulmonary hypertension: levosimendan to evaluate for heart transplantation alone versus combined heart-lung transplantation

7 January 2021

1 reference

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An emerging role for calcium sensitisation in the treatment of heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

Levosimendan: a calcium-sensitizing agent for the treatment of patients with decompensated heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

Hypoxic pulmonary vasoconstriction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

ATP-dependent potassium channels as a key target for the treatment of myocardial and vascular dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats

7 January 2021

1 reference

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Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.

7 January 2021

1 reference

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In vivo gene transfer of prepro-calcitonin gene-related peptide to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse

7 January 2021

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Arterial dilations in response to calcitonin gene-related peptide involve activation of K+ channels

7 January 2021

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Decreased endothelium-dependent pulmonary vasodilator effect of calcitonin gene-related peptide in hypoxic rats contrasts with increased binding sites

7 January 2021

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Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase

7 January 2021

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Agonist-induced vascular tone.

7 January 2021

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Rho/Rho-kinase mediated signaling in physiology and pathophysiology

7 January 2021

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Endothelium-derived mediators and hypoxic pulmonary vasoconstriction

7 January 2021

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Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor

7 January 2021

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Ca2+ sensitization during sustained hypoxic pulmonary vasoconstriction is endothelium dependent

7 January 2021

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Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

7 January 2021

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Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats

7 January 2021

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Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation.

7 January 2021

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3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

Rho-associated kinase modulates myocardial inflammatory cytokine responses

7 January 2021

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Hypoxic pulmonary vasoconstriction increases during endotoxemia in the perfused rat lung

7 January 2021

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Effect of tumor necrosis factor on hypoxic pulmonary vasoconstriction

7 January 2021

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Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase.

7 January 2021

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Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension.

7 January 2021

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Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats

7 January 2021

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Inhibition of sustained hypoxic vasoconstriction by Y-27632 in isolated intrapulmonary arteries and perfused lung of the rat.

7 January 2021

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Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells

7 January 2021

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Depolarization induces Rho-Rho kinase-mediated myosin light chain phosphorylation in kidney tubular cells

7 January 2021

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Effects of Y-27632 on acetylcholine-induced contraction of intact and permeabilized intrapulmonary bronchial smooth muscles in rats

7 January 2021

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Evaluation of Y-27632, a rho-kinase inhibitor, as a bronchodilator in guinea pigs.

7 January 2021

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Y-27632 potentiates relaxant effects of beta 2-adrenoceptor agonists in bovine tracheal smooth muscle

7 January 2021

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Effects of Y-27632, a Rho/Rho kinase inhibitor, on leukotriene D(4)- and histamine-induced airflow obstruction and airway microvascular leakage in guinea pigs in vivo

7 January 2021

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Rho GTPases and the actin cytoskeleton

7 January 2021

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The small GTPase Rho: cellular functions and signal transduction

7 January 2021

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Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases

7 January 2021

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Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina

7 January 2021

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Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension

7 January 2021

1 reference

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Differential regulation of ERK1/2 and p38(MAPK) by components of the Rho signaling pathway during sphingosine-1-phosphate-induced smooth muscle cell migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascades

7 January 2021

1 reference

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Rho inhibition decreases TNF-induced endothelial MAPK activation and monolayer permeability

7 January 2021

1 reference

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Evidence for modulation of smooth muscle force by the p38 MAP kinase/HSP27 pathway

7 January 2021

1 reference

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Invited review: focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

Hypoxia activates jun-N-terminal kinase, extracellular signal-regulated protein kinase, and p38 kinase in pulmonary arteries

7 January 2021

1 reference

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P38 MAPK mediates myocardial proinflammatory cytokine production and endotoxin-induced contractile suppression.

7 January 2021

1 reference

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Role of p38 mitogen-activated protein kinase pathway on renal failure in the infant rat after burn injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

Lung, spleen, and kidney are the major places for inducible nitric oxide synthase expression in endotoxic shock: role of p38 mitogen-activated protein kinase in signal transduction of inducible nitric oxide synthase expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

Endotoxin increases plasma soluble tumor necrosis factor-related apoptosis-inducing ligand level mediated by the p38 mitogen-activated protein kinase signaling pathway.

7 January 2021

1 reference

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PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage

7 January 2021

1 reference

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Sex differences in the myocardial inflammatory response to acute injury

7 January 2021

1 reference

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Mouse genetic background influences severity of immune responses following trauma-hemorrhage.

7 January 2021

1 reference

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Mechanism of salutary effects of estradiol on organ function after trauma-hemorrhage: upregulation of heme oxygenase

7 January 2021

1 reference

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Current understanding of gender dimorphism in hepatic pathophysiology

7 January 2021

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Mechanism responsible for the salutary effects of flutamide on cardiac performance after trauma-hemorrhagic shock: Upregulation of cardiomyocyte estrogen receptors

7 January 2021

1 reference

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Lipopolysaccharide and interleukin 1 augment the effects of hypoxia and inflammation in human pulmonary arterial tissue

7 January 2021

1 reference

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The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2006.03.431

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YJMCC.2006.03.431

1 reference

14 August 2017

1 reference