(Q36481161)

14 August 2017

The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1. (English)

1 reference

14 August 2017

1 reference

P A Wender

1

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14 August 2017

J DeBrabander

2

1 reference

14 August 2017

P G Harran

3

1 reference

14 August 2017

J M Jimenez

4

1 reference

14 August 2017

M F Koehler

5

1 reference

14 August 2017

B Lippa

6

1 reference

14 August 2017

C M Park

7

1 reference

14 August 2017

C Siedenbiedel

8

1 reference

14 August 2017

G R Pettit

9

1 reference

14 August 2017

language of work or name

English

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publication date

1 June 1998

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Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

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14 August 2017

95

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14 August 2017

12

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14 August 2017

6624-6629

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Progress in the discovery of biosynthetic anticancer drugs

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

The role of protein kinase C in cell surface signal transduction and tumour promotion

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

30 September 2017

https://api.crossref.org/works/10.1073%2FPNAS.95.12.6624

Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

The bryostatins inhibit growth of B16/F10 melanoma cells in vitro through a protein kinase C-independent mechanism: dissociation of activities using 26-epi-bryostatin 1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

In vivo administration of the anticancer agent bryostatin 1 activates platelets and neutrophils and modulates protein kinase C activity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

Bryostatin, a non-phorbol macrocyclic lactone, activates intact human polymorphonuclear leukocytes and binds to the phorbol ester receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

Partial parallelism and partial blockade by bryostatin 1 of effects of phorbol ester tumor promoters on primary mouse epidermal cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

Structural modifications of bryostatin 2

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22576

Semianalytical treatment of solvation for molecular mechanics and dynamics

28 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.12.6624

Isolation and structure of bryostatin 1

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.12.6624

Demonstration of sub-nanomolar affinity of bryostatin 1 for the phorbol ester receptor in rat brain

21 January 2018

1 reference

12 December 2020

Immunomodulation in patients receiving intravenous Bryostatin 1 in a phase I clinical study: comparison with effects of Bryostatin 1 on lymphocyte function in vitro

1 reference

12 December 2020

Antineoplastic agents 337. Synthesis of dolastatin 10 structural modifications

1 reference

12 December 2020

Antineoplastic agents. 340. Isolation and structural elucidation of bryostatins 16-18

1 reference

12 December 2020

Rapid assay of binding of tumor-promoting phorbol esters to protein kinase C1

1 reference

12 December 2020

Three activators of protein kinase C, bryostatins, dioleins, and phorbol esters, show differing specificities of action on GH4 pituitary cells

1 reference

12 December 2020

Domain structure and phosphorylation of protein kinase C

1 reference

12 December 2020

Inhibition by bryostatin 1 of the phorbol ester-induced blockage of differentiation in hexamethylene bisacetamide-treated Friend erythroleukemia cells

1 reference

12 December 2020

Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro

1 reference

12 December 2020

Differential effects of bryostatins and phorbol esters on arachidonic acid metabolite release and epidermal growth factor binding in C3H 10T1/2 cells

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.95.12.6624

1 reference

14 August 2017

0 references

1 reference

14 August 2017

PubMed publication ID

9618462

1 reference