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Chemical attenuation of Plasmodium berghei sporozoites induces sterile immunity in mice.
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stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
title
Chemical attenuation of Plasmodium berghei sporozoites induces sterile immunity in mice
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
main subject
Plasmodium berghei
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author
Terence W Spithill
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
Ana Rodriguez
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
author name string
Lisa A Purcell
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1
1 reference
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Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
Stephanie K Yanow
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
Moses Lee
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
language of work or name
English
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publication date
3 January 2008
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
published in
Infection and Immunity
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stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
volume
76
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
page(s)
1193-1199
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
cites work
Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Pharmacogenomic analyses of targeting the AT-rich malaria parasite genome with AT-specific alkylating drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
A case for whole-parasite malaria vaccines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Malaria vaccines: are we getting closer?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
High road, low road? Choices and challenges on the pathway to a malaria vaccine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
The silent path to thousands of merozoites: the Plasmodium liver stage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Antimalarial activity of allicin, a biologically active compound from garlic cloves
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Malaria vaccines in development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
A novel class of in vivo active anticancer agents: achiral seco-amino- and seco-hydroxycyclopropylbenz[e]indolone (seco-CBI) analogues of the duocarmycins and CC-1065.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
HGF/MET signalling protects Plasmodium-infected host cells from apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Parasitology. Malaria vaccines: back to the future?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
A surface phospholipase is involved in the migration of plasmodium sporozoites through cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Intracellular parasite invasion strategies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Rodent malaria in the natural host--irradiated sporozoites of Plasmodium berghei induce liver-stage specific immune responses in the natural host Grammomys surdaster and protect immunized Grammomys against P. berghei sporozoite challenge
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Rationale and plans for developing a non-replicating, metabolically active, radiation-attenuatedPlasmodium falciparumsporozoite vaccine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Genome sequence of the human malaria parasite Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
The economic and social burden of malaria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Malaria vaccines: multiple targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Vaccination against animal parasites.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Sporozoite-induced immunity in mammalian malaria. A review.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Survival and antigenic profile of irradiated malarial sporozoites in infected liver cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
30 September 2017
Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
28 June 2018
Protective T cell immunity against malaria liver stage after vaccination with live sporozoites under chloroquine treatment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
28 June 2018
Comparative studies on the immunogenicity of infective and attenuated sporozoites of Plasmodium berghei
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
28 June 2018
Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasite
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
28 June 2018
Susceptibility of genetically standardized (JAX) mouse strains to sporozoite- and blood-induced Plasmodium berghei infections
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
28 June 2018
Studies on the motility of Plasmodium sporozoites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
28 June 2018
Malaria sporozoite penetration. A new approach by double staining
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
28 June 2018
Protection against malaria induced by irradiated sporozoites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
28 June 2018
Plasmodium berghei: heat-treated sporozoite vaccination of mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
28 June 2018
Potent antimalarial and transmission-blocking activities of centanamycin, a novel DNA-binding agent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Genomics-based drug design targets the AT-rich malaria parasite: implications for antiparasite chemotherapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Priming of CD8+ T cell responses following immunization with heat-killed Plasmodium sporozoites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
The A/T-specific DNA alkylating agent adozelesin inhibits Plasmodium falciparum growth in vitro and protects mice against Plasmodium chabaudi adami infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Genetically modified Plasmodium parasites as a protective experimental malaria vaccine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Hepatocyte growth factor and its receptor are required for malaria infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Effects of irradiation on Plasmodium falciparum sporozoite hepatic development: implications for the design of pre-erythrocytic malaria vaccines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Detection of malaria liver-stages in mice infected through the bite of a single Anopheles mosquito using a highly sensitive real-time PCR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
The complexity of protective immunity against liver-stage malaria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Intrasplenic immunization with infected hepatocytes: a mouse model for studying protective immunity against malaria pre-erythrocytic stage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
21 September 2018
Plasmodium yoelii: Efficient in Vitro Invasion and Complete Development of Sporozoites in Mouse Hepatic Cell Lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258828
retrieved
4 December 2018
In vitro infectivity of irradiated Plasmodium berghei sporozoites to cultured hepatoma cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18174336
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Specificity of Protective Immunity produced by X-irradiated Plasmodium berghei Sporozoites
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18174336
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/IAI.01399-07
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
PMC publication ID
2258828
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
PubMed publication ID
18174336
1 reference
stated in
Europe PubMed Central
PMC publication ID
2258828
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18174336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
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