Wikidata

(Q3648604)

English

Integrin subunit alpha L

mammalian protein found in Homo sapiens

  • leukocyte function-associated molecule 1 alpha chain
  • ITGAL
  • antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide
  • CD11 antigen-like family member A
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
  • lymphocyte function-associated antigen 1, alpha polypeptide
  • LFA-1A
  • leukocyte adhesion glycoprotein LFA-1 alpha chain
  • LFA-1 alpha
  • integrin gene promoter
  • integrin alpha-L
  • CD11a Antigen
In more languages

Statements

molecular function
protein binding
determination method
IPI
6 references
retrieved
8 April 2019
stated in
Human endothelial-cell specific molecule-1 binds directly to the integrin CD11a/CD18 (LFA-1) and blocks binding to intercellular adhesion molecule-1
GOA
curator
UniProt
UniProt protein ID
P20701
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20701
determination method
IPI
retrieved
8 April 2019
stated in
Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor.
GOA
curator
UniProt
UniProt protein ID
P20701
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20701
determination method
IPI
retrieved
8 April 2019
stated in
Integrin CD11a cytoplasmic tail interacts with the CD45 membrane-proximal protein tyrosine phosphatase domain 1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20701
determination method
IPI
retrieved
8 April 2019
stated in
Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20701
determination method
IPI
retrieved
8 April 2019
stated in
Hepatitis C virus infection protein network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20701
determination method
IPI
retrieved
8 April 2019
stated in
Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20701
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE ITGAL 213475 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
D040881
subject named as
CD11a Antigen
0 references
Freebase ID
/m/0fb6cd
0 references
PDB structure ID
 
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