(Q36492875)

English

Binding of the N-terminal region of coactivator TIF2 to the intrinsically disordered AF1 domain of the glucocorticoid receptor is accompanied by conformational reorganizations

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Binding of the N-terminal region of coactivator TIF2 to the intrinsically disordered AF1 domain of the glucocorticoid receptor is accompanied by conformational reorganizations (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Shagufta H Khan

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Smita Awasthi

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Chunhua Guo

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Devrishi Goswami

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Jun Ling

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Patrick R Griffin

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

S Stoney Simons

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Raj Kumar

8

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Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

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publication date

6 November 2012

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Europe PubMed Central

PMC publication ID

14 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

14 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

53

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

44546-44560

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation

1 reference

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Binding-folding induced regulation of AF1 transactivation domain of the glucocorticoid receptor by a cofactor that binds to its DNA binding domain

1 reference

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Proteome-wide evidence for enhanced positive Darwinian selection within intrinsically disordered regions in proteins

1 reference

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TBP binding-induced folding of the glucocorticoid receptor AF1 domain facilitates its interaction with steroid receptor coactivator-1

1 reference

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Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding

1 reference

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Intrinsically disordered proteins: regulation and disease

1 reference

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Unstructural biology coming of age.

1 reference

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Chromatin accessibility pre-determines glucocorticoid receptor binding patterns.

1 reference

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Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors

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Steroid receptor coactivator (SRC) family: masters of systems biology

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Glucocorticoid receptor cofactors as therapeutic targets

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An overview of the importance of conformational flexibility in gene regulation by the transcription factors

1 reference

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Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases

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Site-specific phosphorylation induces functionally active conformation in the intrinsically disordered N-terminal activation function (AF1) domain of the glucocorticoid receptor

1 reference

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ANCHOR: web server for predicting protein binding regions in disordered proteins.

1 reference

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Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family

1 reference

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Structural and functional relationships of the steroid hormone receptors' N-terminal transactivation domain

1 reference

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A progesterone receptor co-activator (JDP2) mediates activity through interaction with residues in the carboxyl-terminal extension of the DNA binding domain

1 reference

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30 September 2017

Prediction of protein binding regions in disordered proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531768

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Kinetic complexity of the global response to glucocorticoid receptor action.

1 reference

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Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA

1 reference

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30 September 2017

Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression

1 reference

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30 September 2017

Interaction of the glucocorticoid receptor with the chromatin landscape

1 reference

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A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions.

1 reference

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Amino-terminal domain of TIF2 is involved in competing for corepressor binding to glucocorticoid and progesterone receptors

1 reference

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Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins

1 reference

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Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: clinical implications for the nervous system response to glucocorticoids and stress

1 reference

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Analysis of molecular recognition features (MoRFs)

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Intrinsic disorder in transcription factors

1 reference

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Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry

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Activation function 1 of glucocorticoid receptor binds TATA-binding protein in vitro and in vivo.

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Intracellular glucocorticoid signaling: a formerly simple system turns stochastic

1 reference

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Regulation of the amino-terminal transcription activation domain of progesterone receptor by a cofactor-induced protein folding mechanism

1 reference

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Gene regulation by the glucocorticoid receptor: structure:function relationship

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30 September 2017

Corepressor binding to progesterone and glucocorticoid receptors involves the activation function-1 domain and is inhibited by molybdate

1 reference

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Transcriptional regulation and the role of diverse coactivators in animal cells

1 reference

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TATA box binding protein induces structure in the recombinant glucocorticoid receptor AF1 domain.

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Glucocorticoid receptor ligand binding domain is sufficient for the modulation of glucocorticoid induction properties by homologous receptors, coactivator transcription intermediary factor 2, and Ubc9.

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Role of molecular chaperones in steroid receptor action

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Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors

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Transactivation functions of the N-terminal domains of nuclear hormone receptors: protein folding and coactivator interactions

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1 reference

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Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

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Mechanism of corepressor binding and release from nuclear hormone receptors.

1 reference

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Molecular determinants of nuclear receptor-corepressor interaction

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The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors

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The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors.

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Trimethylamine N-oxide-induced cooperative folding of an intrinsically unfolded transcription-activating fragment of human glucocorticoid receptor.

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Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

1 reference

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Structural biology. Versatility from protein disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/23132854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human transcription factors contain a high fraction of intrinsically disordered regions essential for transcriptional regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23132854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interdomain signaling in a two-domain fragment of the human glucocorticoid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23132854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The conformation of the glucocorticoid receptor af1/tau1 domain induced by osmolyte binds co-regulatory proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/23132854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoid receptor binding to calf thymus DNA. 2. Role of a DNA-binding activity factor in receptor heterogeneity and a multistep mechanism of receptor activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23132854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molybdate inhibition of glucocorticoid receptor inactivation and transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23132854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoid receptor binding to calf thymus DNA. 1. Identification and characterization of a macromolecular factor involved in receptor-steroid complex binding to DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/23132854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.411330

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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