(Q36497439)

14 August 2017

Heart failure drug digitoxin induces calcium uptake into cells by forming transmembrane calcium channels (English)

1 reference

14 August 2017

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transmembrane protein

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author name string

Nelson Arispe

1

1 reference

14 August 2017

Juan Carlos Diaz

2

1 reference

14 August 2017

Olga Simakova

3

1 reference

14 August 2017

Harvey B Pollard

4

1 reference

14 August 2017

language of work or name

English

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publication date

12 February 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

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14 August 2017

105

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14 August 2017

7

1 reference

14 August 2017

2610-2615

1 reference

The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+-Ca2+ exchanger function

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Digitalis: new actions for an old drug

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Proapoptotic triterpene electrophiles (avicins) form channels in membranes: cholesterol dependence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Effect of sterols on beta-amyloid peptide (AbetaP 1-40) channel formation and their properties in planar lipid membranes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

From "carpet" mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Treatment of congestive heart failure--current status of use of digitoxin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Barrel-stave model or toroidal model? A case study on melittin pores.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Alamethicin: A Peptide Model for Voltage Gating and Protein-Membrane Interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Potassium changes the relationship between receptor occupancy and the inotropic effect of cardiac glycosides in guinea-pig myocardium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Is the cell membrane Na+, K+ -ATPase enzyme system the pharmacological receptor for digitalis?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Increase in dissociation rate constants of cardiotonic steroid-brain (Na+ + K+)-ATPase complexes by reduction of the unsaturated lactone

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Statistical analysis of alamethicin channels in black lipid membranes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Time course for reversal of digoxin toxicity with digoxin-specific antibody fragments

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268184

Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking

28 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0712270105

Is digitalis inotropy associated with enhanced slow inward calcium current?

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0712270105

Comparing the toxicity of digoxin and digitoxin in a geriatric population: should an old drug be rediscovered?

21 January 2018

1 reference

12 December 2020

Reversal of advanced digoxin intoxication with Fab fragments of digoxin-specific antibodies

1 reference

12 December 2020

Enhancement of calcium current during digitalis inotrophy in mammalian heart: positive feed-back regulation by intracellular calcium?

1 reference

12 December 2020

Treatment of 63 severely digitalis-toxic patients with digoxin-specific antibody fragments

1 reference

12 December 2020

Effect of two different doses of nitrendipine on steady-state plasma digoxin level and systolic time intervals

1 reference

12 December 2020

The reaction of ouabain with the sodium pump of guinea-pig myocardium in relation to its inotropic effect

1 reference

12 December 2020

Magainin 2, a natural antibiotic from frog skin, forms ion channels in lipid bilayer membranes

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0712270105

1 reference

14 August 2017

0 references

1 reference

14 August 2017

PubMed publication ID

18272488

1 reference