(Q36507302)

14 August 2017

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title

Endothelial dysfunction in diabetic erectile dysfunction (English)

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14 August 2017

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Musicki B

1

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PubMed ID

16775612

14 August 2017

Burnett AL

series ordinal

2

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14 August 2017

15 June 2006

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International Journal of Impotence Research

14 August 2017

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14 August 2017

19

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14 August 2017

129-138

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14 August 2017

2

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https://scigraph.springernature.com/pub.10.1038/sj.ijir.3901494

14 August 2017

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cites work

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21 January 2018

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Effect of lifestyle changes on erectile dysfunction in obese men: a randomized controlled trial

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Changes in mating behavior, erectile function, and nitric oxide levels in penile corpora cavernosa in streptozotocin-diabetic rats.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Elevation of intracavernous pressure and NO-cGMP activity by a new herbal formula in penile tissues of aged and diabetic rats

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Endothelial nitric oxide synthase protein expression, localization, and activity in the penis of the alloxan-induced diabetic rat.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Effect of combination endothelial nitric oxide synthase gene therapy and sildenafil on erectile function in diabetic rats

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Arginase-boronic acid complex highlights a physiological role in erectile function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Sphingosine 1-phosphate induces endothelial nitric-oxide synthase activation through phosphorylation in human corpus cavernosum

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Cholesterol feeding reduces vascular endothelial growth factor signaling in rabbit corporal tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Dynamic activation of endothelial nitric oxide synthase by Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Up-regulation of the association between heat shock protein 90 and endothelial nitric oxide synthase prevents high glucose-induced apoptosis in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Diabetic mouse angiopathy is linked to progressive sympathetic receptor deletion coupled to an enhanced caveolin-1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Penile erection requires association of soluble guanylyl cyclase with endothelial caveolin-1 in rat corpus cavernosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Vascular consequences of endothelial nitric oxide synthase uncoupling for the activity and expression of the soluble guanylyl cyclase and the cGMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Oxidized low-density lipoprotein increases superoxide production by endothelial nitric oxide synthase by inhibiting PKCalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Cavernosal tissue nitrite, nitrate, malondialdehyde and glutathione levels in diabetic and non-diabetic erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

The role of free radical in the pathogenesis of impotence in streptozotocin-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Effect of ascorbic acid treatment on endothelium-dependent and neurogenic relaxation of corpus cavernosum from middle-aged non-insulin dependent diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

The effect of superoxide dismutase on nitric oxide-mediated and electrical field-stimulated diabetic rabbit cavernosal smooth muscle relaxation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Effects of the peroxynitrite decomposition catalyst, FeTMPyP, on function of corpus cavernosum from diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Vascular NAD(P)H oxidases: specific features, expression, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: the role of protein kinase C and NAD(P)H-oxidase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Mechanisms underlying endothelial dysfunction in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Sildenafil inhibits the formation of superoxide and the expression of gp47 NAD[P]H oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Diabetes induces endothelial dysfunction but does not increase neointimal formation in high-fat diet fed C57BL/6J mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Biochemistry and molecular cell biology of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Synergistic action of advanced glycation end products and endogenous nitric oxide leads to neuronal apoptosis in vitro: a new insight into selective nitrergic neuropathy in diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

The protective effect of aminoguanidine on erectile function in streptozotocin diabetic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

The protective effect of aminoguanidine on erectile function in diabetic rats is not related to the timing of treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Advanced glycation end-products are responsible for the impairment of corpus cavernosal smooth muscle relaxation seen in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Impairment of corpus cavernosal smooth muscle relaxation by glycosylated human haemoglobin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Role of PKCalpha and PKCiota in phenylephrine-induced contraction of rat corpora cavernosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Protein kinase C beta inhibition and aorta and corpus cavernosum function in streptozotocin-diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Endothelium-derived hyperpolarizing factor: a cousin to nitric oxide and prostacyclin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Diabetes impairs endothelium-dependent relaxation of human penile vascular tissues mediated by NO and EDHF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Enhancement of both EDHF and NO/cGMP pathways is necessary to reverse erectile dysfunction in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

RhoA-mediated Ca2+ sensitization in erectile function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

RhoA-Rho kinase mediates synergistic ET-1 and phenylephrine contraction of rat corpus cavernosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Nitric oxide inhibits RhoA/Rho-kinase signaling to cause penile erection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Proerectile effects of the Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine (H-1152) in the rat penis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Increased contractility of diabetic rabbit corpora smooth muscle in response to endothelin is mediated via Rho-kinase beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Vascular endothelial growth factor restores erectile function through modulation of the insulin-like growth factor system and sex hormone receptors in diabetic rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Diminished penile expression of vascular endothelial growth factor and its receptors at the insulin-resistant stage of a type II diabetic rat model: a possible cause for erectile dysfunction in diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Vascular endothelial growth factor restores erectile function through inhibition of apoptosis in diabetic rat penile crura

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Effect of basic fibroblast growth factor incorporating gelatin microspheres on erectile function in the diabetic rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Improvement of erectile function in diabetic rats by insulin: possible role of the insulin-like growth factor system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

The effect of PDE5 inhibition on the erectile function in streptozotocin-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Effects of diabetes on nitric oxide synthase and growth factor genes and protein expression in an animal model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

Association of hypogonadism and type II diabetes in men attending an outpatient erectile dysfunction clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

High proportions of erectile dysfunction in men with the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Characterization and localization of nitric oxide synthase isoforms in the BB/WOR diabetic rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

The effects of long-term oral administration of L-arginine on the erectile response of rabbits with alloxan-induced diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Impaired endothelium-dependent and neurogenic relaxation of corpus cavernosum from diabetic rats: improvement with L-arginine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Glycated low-density lipoprotein attenuates shear stress-induced nitric oxide synthesis by inhibition of shear stress-activated L-arginine uptake in endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Combined angiopoietin-1 and vascular endothelial growth factor gene transfer restores cavernous angiogenesis and erectile function in a rat model of hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Nitric oxide: a physiologic mediator of penile erection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Correction of nitrergic neurovascular dysfunction in diabetic mouse corpus cavernosum by p38 mitogen-activated protein kinase inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Comparison of oxidative/antioxidative status of penile corpus cavernosum blood and peripheral venous blood

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Oxidative stress and antioxidant therapy: their impact in diabetes-associated erectile dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Effects of vitamin E and sodium selenate on neurogenic and endothelial relaxation of corpus cavernosum in the diabetic mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Effects of chelator treatment on aorta and corpus cavernosum from diabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Effects of Aldose Reductase Inhibition on Responses of the Corpus Cavernosum and Mesenteric Vascular Bed of Diabetic Rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Advanced glycation end products in human penis: elevation in diabetic tissue, site of deposition, and possible effect through iNOS or eNOS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Glucose-induced changes in protein kinase C and nitric oxide are prevented by vitamin E

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Human and rabbit cavernosal smooth muscle cells express Rho-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Adeno-associated viral gene transfer of dominant negative RhoA enhances erectile function in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJIR.3901494

7 January 2021

Identifiers

DOI

10.1038/SJ.IJIR.3901494

1 reference

14 August 2017

1 reference

PubMed ID

16775612