(Q36517148)

English

Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model

scientific article published on December 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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1 reference

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author name string

Li Gan

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Marcelo R Vargas

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Delinda A Johnson

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Jeffrey A Johnson

4

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Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

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publication date

1 December 2012

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Europe PubMed Central

PMC publication ID

14 August 2017

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

14 August 2017

32

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Europe PubMed Central

PMC publication ID

14 August 2017

49

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

17775-17787

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3539799/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1

1 reference

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α-Synuclein fate is determined by USP9X-regulated monoubiquitination

1 reference

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1 reference

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1 reference

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Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition

1 reference

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Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

1 reference

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Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis

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Alpha-synuclein and transgenic mouse models

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Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

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alpha-Synuclein locus triplication causes Parkinson's disease

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Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies

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Endoproteolytic activity of the proteasome

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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1 reference

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Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

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12 December 2020

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https://pubmed.ncbi.nlm.nih.gov/23223297

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Neuropathology in mice expressing human alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23223297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3049-12.2012

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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