(Q36523459)

14 August 2017

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title

Involvement of nitrogen-containing compounds in beta-lactam biosynthesis and its control (English)

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14 August 2017

Arnold L Demain

1

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14 August 2017

Preeti Vaishnav

series ordinal

2

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14 August 2017

language of work or name

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1 April 2006

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Critical Reviews in Biotechnology

14 August 2017

published in

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14 August 2017

volume

26

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14 August 2017

issue

2

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14 August 2017

page(s)

67-82

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Nitrogen Metabolite Regulation of Antibiotic Biosynthesis

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Characterization and lysine control of expression of the lys1 gene of Penicillium chrysogenum encoding homocitrate synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Overexpression of the lys1 gene in Penicillium chrysogenum: homocitrate synthase levels, alpha-aminoadipic acid pool and penicillin production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Theoretical conversion yields for penicillin synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

A gene encoding lysine 6-aminotransferase, which forms the beta-lactam precursor alpha-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

The beta-lactam antibiotics: past, present, and future

21 January 2018

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https://api.crossref.org/works/10.1080%2F07388550600671466

Identification, characterization, and regulation of a cluster of genes involved in carbapenem biosynthesis in Photorhabdus luminescens

21 January 2018

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https://api.crossref.org/works/10.1080%2F07388550600671466

Methionine control of cephalosporin C formation

21 January 2018

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https://api.crossref.org/works/10.1080%2F07388550600671466

Effect of primary metabolites on secondary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Uptake and metabolism of ?-aminoadipic acid by Penicillium chrysogenum wis 54-1255

21 January 2018

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https://api.crossref.org/works/10.1080%2F07388550600671466

Molecular cloning and analysis of nre, the major nitrogen regulatory gene of Penicillium chrysogenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Characterization of the lys2 gene of Acremonium chrysogenum encoding a functional alpha-aminoadipate activating and reducing enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Clavulanic acid biosynthesis in Streptomyces clavuligerus: gene cloning and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Stereochemistry of methylation in thienamycin biosynthesis: example of a methyl transfer from methionine with retention of configuration

21 January 2018

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https://api.crossref.org/works/10.1080%2F07388550600671466

Sulfazecin and isosulfazecin, novel beta-lactam antibiotics of bacterial origin

21 January 2018

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https://api.crossref.org/works/10.1080%2F07388550600671466

Biosynthesis and molecular genetics of clavulanic acid

21 January 2018

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https://api.crossref.org/works/10.1080%2F07388550600671466

Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Metabolic flux distributions in Penicillium chrysogenum during fed-batch cultivations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Methionine interference in rapamycin production involves repression of demethylrapamycin methyltransferase and S-adenosylmethionine synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

A moderate amplification of the mecB gene encoding cystathionine-gamma-lyase stimulates cephalosporin biosynthesis in Acremonium chrysogenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Biosynthesis and molecular genetics of cephamycins. Cephamycins produced by actinomycetes

21 January 2018

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https://api.crossref.org/works/10.1080%2F07388550600671466

Clavulanic acid, a beta-lactamase inhibitor: biosynthesis and molecular genetics

21 January 2018

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https://api.crossref.org/works/10.1080%2F07388550600671466

Transcriptional control of expression of fungal beta-lactam biosynthesis genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Targeted inactivation of the mecB gene, encoding cystathionine-gamma-lyase, shows that the reverse transsulfuration pathway is required for high-level cephalosporin biosynthesis in Acremonium chrysogenum C10 but not for methionine induction of the c

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Regulation of alpha-aminoadipate reductase from Penicillium chrysogenum in relation to the flux from alpha-aminoadipate into penicillin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Cloning and location of a gene governing lysine epsilon-aminotransferase, an enzyme initiating beta-lactam biosynthesis in Streptomyces spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Precursor flux control through targeted chromosomal insertion of the lysine epsilon-aminotransferase (lat) gene in cephamycin C biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Characterization of the reverse transsulfuration gene mecB of Acremonium chrysogenum, which encodes a functional cystathionine-gamma-lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Molecular control of expression of penicillin biosynthesis genes in fungi: regulatory proteins interact with a bidirectional promoter region

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Unraveling the methionine-cephalosporin puzzle in Acremonium chrysogenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Lysine is catabolized to 2-aminoadipic acid in Penicillium chrysogenum by an omega-aminotransferase and to saccharopine by a lysine 2-ketoglutarate reductase. Characterization of the omega-aminotransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Cloning, characterization, and use in strain improvement of the Cephalosporium acremonium gene cefG encoding acetyl transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Molecular genetics of carbapenem antibiotic biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Carbapenem antibiotic production in Erwinia carotovora is regulated by CarR, a homologue of the LuxR transcriptional activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Characterization of the oat1 gene of Penicillium chrysogenum encoding an omega-aminotransferase: induction by L-lysine, L-ornithine and L-arginine and repression by ammonium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Emerging strategies in infectious diseases: new carbapenem and trinem antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Monocyclic beta-lactam antibiotics produced by bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

The paralogous pairs of genes involved in clavulanic acid and clavam metabolite biosynthesis are differently regulated in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Localization of the lysine epsilon-aminotransferase (lat) and delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine epsilon-aminotransferase activity in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Energetics of growth and penicillin production in a high-producing strain of Penicillium chrysogenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Exogenous methionine increases levels of mRNAs transcribed from pcbAB, pcbC, and cefEF genes, encoding enzymes of the cephalosporin biosynthetic pathway, in Acremonium chrysogenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Possible involvement of the lysine epsilon-aminotransferase gene (lat) in the expression of the genes encoding ACV synthetase (pcbAB) and isopenicillin N synthase (pcbC) in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Nitrogen nutrition and regulation of cephalosporin production in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Cell-free synthesis of delta-(L-alpha-aminoadipyl)-L-cysteine, the first intermediate of penicillin and cephalosporin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Relationship between nitrogen assimilation and cephalosporin synthesis in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Ammonium repression of cephalosporin production by Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

A chemically defined medium for cephalosporin C production by Paecilomyces persicinus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Inhibition of penicillin formation by lysine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Cephalosporin C production by Cephalosporium acremonium: the methionine story

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Dependence of nitrogen- and phosphorus-regulation of beta-lactam antibiotic production by Streptomyces clavuligerus on aeration level

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Acidic and basic amino acid transport systems of Penicillium chrysogenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Manipulation of the physiology of clavulanic acid production in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

alpha-Aminoadipate pool concentration and penicillin biosynthesis in strains of Penicillium chrysogenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Solid state fermentation for cephalosporin production by Streptomyces clavuligerus and Cephalosporium acremonium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

A role for alanine in the ammonium regulation of cephalosporin biosynthesis in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

D-methionine and the biosynthesis of cephalosporin N

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Induction of penicillin biosynthesis by L-glutamate in penicillium chrysogenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Effects of enhanced lysine epsilon-aminotransferase activity on cephamycin biosynthesis in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Lysine control of penicillin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Molecular characterization of a fungal secondary metabolism promoter: transcription of the Aspergillus nidulans isopenicillin N synthetase gene is modulated by upstream negative elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Dissociation of cephamycin and clavulanic acid biosynthesis in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Partial purification, characterization and nitrogen regulation of the lysine ?-aminotransferase of Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Biosynthesis of clavulanic acid: origin of the C5 unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Biosynthesis of clavulanic acid: origin of the C3 unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

The biosynthetic genes for clavulanic acid and cephamycin production occur as a 'super-cluster' in three Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Purification from Cephalosporium acremonium of the initial enzyme unique to the biosynthesis of penicillins and cephalosporins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07388550600671466

Thienamycin, a new beta-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.32.1

Nocardicin A, a new monocyclic beta-lactam antibiotic. I. Discovery, isolation and characterization

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.29.492

Identifiers

DOI

10.1080/07388550600671466

1 reference

14 August 2017

1 reference