(Q36525806)

14 August 2017

1 reference

title

Applications of ESI-MS in drug discovery: interrogation of noncovalent complexes (English)

1 reference

14 August 2017

1 reference

Steven A Hofstadler

1

1 reference

PubMed ID

16816839

14 August 2017

Kristin A Sannes-Lowery

series ordinal

2

1 reference

14 August 2017

1 July 2006

1 reference

Nature Reviews Drug Discovery

14 August 2017

1 reference

14 August 2017

5

1 reference

14 August 2017

585-595

1 reference

14 August 2017

7

1 reference

https://scigraph.springernature.com/pub.10.1038/nrd2083

14 August 2017

0 references

cites work

FT-ICR mass spectrometry in the drug discovery process

1 reference

Early discovery drug screening using mass spectrometry

31 March 2020

1 reference

Analysis of noncovalent complexes of DNA and RNA by mass spectrometry

31 March 2020

1 reference

Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA

31 March 2020

1 reference

Preservation of non-covalent associations in electrospray ionization mass spectrometry: Multiply charged polypeptide and protein dimers

31 March 2020

1 reference

Bioanalytical mass spectrometry: many flavors to choose.

31 March 2020

1 reference

Studying noncovalent protein complexes by electrospray ionization mass spectrometry

31 March 2020

1 reference

Bio-affinity characterization mass spectrometry

31 March 2020

1 reference

Native protein mass spectrometry: from intact oligomers to functional machineries.

31 March 2020

1 reference

The study of protein–ligand interactions by mass spectrometry—a personal view

31 March 2020

1 reference

Electrospray ionization mass spectrometry of oligonucleotide complexes with drugs, metals, and proteins.

31 March 2020

1 reference

A method for the determination of binding constants by electrospray ionization mass spectrometry

31 March 2020

1 reference

Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry

31 March 2020

1 reference

Measuring dissociation constants of RNA and aminoglycoside antibiotics by electrospray ionization mass spectrometry

31 March 2020

1 reference

Defining the structure and stability of macromolecular assemblies in solution: the re-emergence of analytical ultracentrifugation as a practical tool

31 March 2020

1 reference

Measuring protein-protein interactions.

31 March 2020

1 reference

Interactions of α- and β-avoparcin with bacterial cell-wall receptor-mimicking peptides studied by electrospray ionization mass spectrometry

31 March 2020

1 reference

Covalent and non-covalent dissociations of gas-phase complexes of avoparcin and bacterial receptor mimicking precursor peptides studied by collisionally activated decomposition mass spectrometry

31 March 2020

1 reference

Carbonic Anhydrase-Inhibitor Binding: From Solution to the Gas Phase

31 March 2020

1 reference

Binding of aldose reductase inhibitors: correlation of crystallographic and mass spectrometric studies

31 March 2020

1 reference

Gas-phase binding of non-covalent protein complexes between bovine pancreatic trypsin inhibitor and its target enzymes studied by electrospray ionization tandem mass spectrometry

31 March 2020

1 reference

Using Electrospray Ionization FTICR Mass Spectrometry To Study Competitive Binding of Inhibitors to Carbonic Anhydrase

31 March 2020

1 reference

Screening derivatized peptide libraries for tight binding inhibitors to carbonic anhydrase II by electrospray ionization-mass spectrometry

31 March 2020

1 reference

Probing the energetics of dissociation of carbonic anhydrase-ligand complexes in the gas phase.

31 March 2020

1 reference

Fourier transform-ion cyclotron resonance mass spectrometric resolution, identification, and screening of non-covalent complexes of Hck Src homology 2 domain receptor and ligands from a 324-member peptide combinatorial library

31 March 2020

1 reference

SH2 domains: from structure to energetics, a dual approach to the study of structure-function relationships

31 March 2020

1 reference

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

31 March 2020

1 reference

Infrared multiphoton dissociation of large multiply charged ions for biomolecule sequencing

31 March 2020

1 reference

High-resolution electrospray ionization Fourier transform mass spectrometry with infrared multiphoton dissociation of glucokinase from Bacillus Stearothermophilus

31 March 2020

1 reference

Mass spectrometric and thermodynamic studies reveal the role of water molecules in complexes formed between SH2 domains and tyrosyl phosphopeptides

31 March 2020

1 reference

Probing the nature of interactions in SH2 binding interfaces--evidence from electrospray ionization mass spectrometry

31 March 2020

1 reference

Measurement of dissociation constants of inhibitors binding to Src SH2 domain protein by non-covalent electrospray ionization mass spectrometry.

31 March 2020

1 reference

Medicinal chemistry of aldose reductase inhibitors

31 March 2020

1 reference

Screening transthyretin amyloid fibril inhibitors: characterization of novel multiprotein, multiligand complexes by mass spectrometry

31 March 2020

1 reference

Tandem mass spectrometry defines the stoichiometry and quaternary structural arrangement of tryptophan molecules in the multiprotein complex TRAP.

31 March 2020

1 reference

Targeting C-reactive protein for the treatment of cardiovascular disease.

31 March 2020

1 reference

Amyloid fibril formation and protein misassembly: a structural quest for insights into amyloid and prion diseases

31 March 2020

1 reference

Amyloid diseases: abnormal protein aggregation in neurodegeneration

31 March 2020

1 reference

Electrospray ionization mass spectrometry as a tool for determination of drug binding sites to human serum albumin by noncovalent interaction

31 March 2020

1 reference

Interaction between antitumor drugs and a double-stranded oligonucleotide studied by electrospray ionization mass spectrometry

31 March 2020

1 reference

Determination of affinity, stoichiometry and sequence selectivity of minor groove binder complexes with double-stranded oligodeoxynucleotides by electrospray ionization mass spectrometry

31 March 2020

1 reference

Positive ion electrospray ionization mass spectrometry of double-stranded DNA/drug complexes

31 March 2020

1 reference

Comparison of the binding stoichiometries of positively charged DNA-binding drugs using positive and negative ion electrospray ionization mass spectrometry

31 March 2020

1 reference

Gas-phase stability of double-stranded oligodeoxynucleotides and their noncovalent complexes with DNA-binding drugs as revealed by collisional activation in an ion trap

31 March 2020

1 reference

Evaluation of complexes of DNA duplexes and novel benzoxazoles or benzimidazoles by electrospray ionization mass spectrometry

31 March 2020

1 reference

Non-covalent complexes between DNA-binding drugs and double-stranded deoxyoligonucleotides: a study by ionspray mass spectrometry

31 March 2020

1 reference

Detection of oligonucleotide-ligand complexes by ESI-MS (DOLCE-MS) as a component of high throughput screening

31 March 2020

1 reference

Adaptive recognition by nucleic acid aptamers

31 March 2020

1 reference

Recent solution structures of RNA and its complexes with drugs, peptides and proteins

31 March 2020

1 reference

31 March 2020

1 reference

Multiplexed screening of neutral mass-tagged RNA targets against ligand libraries with electrospray ionization FTICR MS: a paradigm for high-throughput affinity screening

31 March 2020

1 reference

The synthesis and 16S A-site rRNA recognition of carbohydrate-free aminoglycosides

31 March 2020

1 reference

Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry.

31 March 2020

1 reference

SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain

31 March 2020

1 reference

SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets

31 March 2020

1 reference

RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide

31 March 2020

1 reference

Multitarget Affinity/Specificity Screening of Natural Products: Finding and Characterizing High-Affinity Ligands from Complex Mixtures by Using High-Performance Mass Spectrometry

31 March 2020

1 reference

Structure-activity relationships by mass spectrometry: identification of novel MMP-3 inhibitors

31 March 2020

1 reference

Advantages and drawbacks of nanospray for studying noncovalent protein-DNA complexes by mass spectrometry

31 March 2020

1 reference

Disassembly of intact multiprotein complexes in the gas phase

31 March 2020

1 reference

Influence of droplet size, capillary-cone distance and selected instrumental parameters for the analysis of noncovalent protein-ligand complexes by nano-electrospray ionization mass spectrometry

31 March 2020

1 reference

Use of a microchip device coupled with mass spectrometry for ligand screening of a multi-protein target

31 March 2020

1 reference

Quantitative determination of noncovalent binding interactions using automated nanoelectrospray mass spectrometry

31 March 2020

1 reference

Automated nano-electrospray mass spectrometry for protein-ligand screening by noncovalent interaction applied to human H-FABP and A-FABP.

31 March 2020

1 reference

Hydrolysis of lignocellulosic materials for ethanol production: a review

31 March 2020

1 reference

Application of ion mobility to the gas-phase conformational analysis of polyhedral oligomeric silsesquioxanes (POSS)

31 March 2020

1 reference

Evidence for many resolvable structures within conformation types of electrosprayed ubiquitin ions

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRD2083

1 reference

14 August 2017

1 reference

PubMed ID

16816839