(Q36541590)

14 August 2017

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title

Stimulants: Therapeutic actions in ADHD. (English)

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14 August 2017

Amy F T Arnsten

1

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PubMed ID

16855530

14 August 2017

language of work or name

English

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publication date

19 July 2006

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14 August 2017

Neuropsychopharmacology

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14 August 2017

31

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14 August 2017

11

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14 August 2017

2376-2383

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.npp.1301164

14 August 2017

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cites work

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Methylphenidate improves prefrontal cortical cognitive function through alpha2 adrenoceptor and dopamine D1 receptor actions: Relevance to therapeutic effects in Attention Deficit Hyperactivity Disorder

21 January 2018

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Alpha 2-adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates.

21 January 2018

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Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions

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Protein kinase A as a therapeutic target for memory disorders: rationale and challenges

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The contribution of alpha 2-noradrenergic mechanisms of prefrontal cortical cognitive function. Potential significance for attention-deficit hyperactivity disorder

21 January 2018

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Methylphenidate improves response inhibition in adults with attention-deficit/hyperactivity disorder

21 January 2018

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The cognitive neuroscience of response inhibition: relevance for genetic research in attention-deficit/hyperactivity disorder

21 January 2018

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Inhibition and the right inferior frontal cortex

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

The alpha-2A-adrenoceptor agonist, guanfacine, increases regional cerebral blood flow in dorsolateral prefrontal cortex of monkeys performing a spatial working memory task.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Frontal decortication in rhesus monkeys: A test of the interference hypothesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Selective inhibition in children with attention-deficit hyperactivity disorder off and on stimulant medication

21 January 2018

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The cognitive genetics of attention deficit hyperactivity disorder (ADHD): sustained attention as a candidate phenotype.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

DRD4 gene variants and sustained attention in attention deficit hyperactivity disorder (ADHD): effects of associated alleles at the VNTR and -521 SNP.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive function.

21 January 2018

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Pediatric mania: a developmental subtype of bipolar disorder?

21 January 2018

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Protein kinase C overactivity impairs prefrontal cortical regulation of working memory.

21 January 2018

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Executive functioning in adult ADHD: a meta-analytic review

21 January 2018

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Functional neuroimaging of attention-deficit/hyperactivity disorder: a review and suggested future directions

21 January 2018

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Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder

21 January 2018

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Reserpine impairs spatial working memory performance in monkeys: reversal by the alpha 2-adrenergic agonist clonidine.

21 January 2018

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Implication of right frontostriatal circuitry in response inhibition and attention-deficit/hyperactivity disorder

21 January 2018

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Quantitative Brain Magnetic Resonance Imaging in Attention-Deficit Hyperactivity Disorder

21 January 2018

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Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder.

21 January 2018

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Dissociation in prefrontal cortex of affective and attentional shifts

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Effects of methylphenidate on spatial working memory and planning in healthy young adults.

21 January 2018

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Molecular genetics of attention-deficit/hyperactivity disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder with normal controls.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

The alpha-2a noradrenergic agonist, guanfacine, improves delayed response performance in young adult rhesus monkeys.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Prefrontal neuronal activity in rhesus monkeys performing a delayed anti-saccade task.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Divided and focused attention in patients with lesion of the prefrontal cortex.

21 January 2018

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Cellular basis of working memory

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Long-term use of stimulants in children with attention deficit hyperactivity disorder: safety, efficacy, and long-term outcome

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Magnetic resonance imaging correlates of attention-deficit/hyperactivity disorder in children.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Orbitofrontal cortex dysfunction in attention-deficit hyperactivity disorder revealed by reversal and extinction tasks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Guanfacine, but not clonidine, improves planning and working memory performance in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

MRI parcellation of the frontal lobe in boys with attention deficit hyperactivity disorder or Tourette syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Effects of bromocriptine on human subjects depend on working memory capacity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Prefrontal cortex gating of auditory transmission in humans

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Common inhibitory mechanism in human inferior prefrontal cortex revealed by event-related functional MRI.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Stimulant actions in rodents: implications for attention-deficit/hyperactivity disorder treatment and potential substance abuse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Alpha-2 adrenergic modulation of prefrontal cortical neuronal activity related to spatial working memory in monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Delayed-response deficit induced by local injection of the alpha 2-adrenergic antagonist yohimbine into the dorsolateral prefrontal cortex in young adult monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Locomotor hyperactivity induced by blockade of prefrontal cortical alpha2-adrenoceptors in monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Decision-making processes following damage to the prefrontal cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Local infusion of an alpha-1 adrenergic agonist into the prefrontal cortex impairs spatial working memory performance in monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Characteristic neurocognitive profile associated with adult attention-deficit/hyperactivity disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Methylphenidate improves working memory and set-shifting in AD/HD: relationships to baseline memory capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

A rapid presentation event-related functional magnetic resonance imaging study of response inhibition in macaque monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

The cerebral cortex of the rat and visual attentional function: dissociable effects of mediofrontal, cingulate, anterior dorsolateral, and parietal cortex lesions on a five-choice serial reaction time task.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Lack of effects of guanfacine on executive and memory functions in healthy male volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Association and linkage of alpha-2A adrenergic receptor gene polymorphisms with childhood ADHD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

The beta-1 adrenergic antagonist, betaxolol, improves working memory performance in rats and monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin: a placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Is the alpha-2A adrenergic receptor gene (ADRA2A) associated with attention-deficit/hyperactivity disorder?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Hypofrontality in attention deficit hyperactivity disorder during higher-order motor control: a study with functional MRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Neuropsychological performance in adult attention-deficit hyperactivity disorder: meta-analysis of empirical data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Structural brain imaging of attention-deficit/hyperactivity disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

The effects of prefrontal intracortical microinjections of an alpha-2 agonist, alpha-2 antagonist and lidocaine on the delayed alternation performance of aged rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Effects of frontal lobe damage on interference effects in working memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Neurocognitive effects of methylphenidate in adult attention-deficit/hyperactivity disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

The Stroop revisited: a meta-analysis of interference control in AD/HD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: results from imaging studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Brain DA D2 receptors predict reinforcing effects of stimulants in humans: replication study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Single neurons in prefrontal cortex encode abstract rules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Enhanced visuomotor associative learning following stimulation of alpha 2A-adrenoceptors in the ventral prefrontal cortex in monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Prefrontal unit activity during delayed conditional Go/No-Go discrimination in the monkey. I. Relation to the stimulus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Frontal lesions and sustained attention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Modulation of memory fields by dopamine D1 receptors in prefrontal cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Electrophysiologic evidence of increased distractibility after dorsolateral prefrontal lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Gating of somatosensory input by human prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Developmental instability and working memory ability in children: a magnetic resonance spectroscopy investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Psychostimulant Treatment and Risk for Substance Abuse Among Young Adults with a History of Attention-Deficit/Hyperactivity Disorder: APopulation-Based, Birth Cohort Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

Impairment of social and moral behavior related to early damage in human prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

The alpha-2 adrenergic agonist guanfacine improves memory in aged monkeys without sedative or hypotensive side effects: evidence for alpha-2 receptor subtypes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

A role for norepinephrine in stress-induced cognitive deficits: alpha-1-adrenoceptor mediation in the prefrontal cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Locomotor effects of regional ablations of frontal cortex in rhesus monkeys.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Locomotor activity following lateral frontal lesions in rhesus monkeys.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Exposure of adolescent rats to oral methylphenidate: preferential effects on extracellular norepinephrine and absence of sensitization and cross-sensitization to methamphetamine.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Activity of neurons in anterior inferior temporal cortex during a short-term memory task.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

D1- versus D2-receptor modulation of visuospatial working memory in humans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

The effect of periarcuate lesions in the monkey on the performance of symmetrically and asymmetrically reinforced visual and auditory go, no-go tasks.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Responses to methylphenidate in Attention-Deficit/Hyperactivity Disorder and normal children: update 2002

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Attenuation of delay-period activity of monkey prefrontal neurons by an alpha2-adrenergic antagonist during an oculomotor delayed-response task.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

An escalating dose "binge" model of amphetamine psychosis: behavioral and neurochemical characteristics.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

The alpha-2A noradrenergic receptor agonist guanfacine improves visual object discrimination reversal performance in aged rhesus monkeys.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Supranormal stimulation of D1 dopamine receptors in the rodent prefrontal cortex impairs spatial working memory performance.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301164

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1301164

1 reference

PubMed ID

16855530

Dimensions Publication ID

14 August 2017

0 references

1 reference

PubMed ID

16855530