(Q36543753)

English

Rapid nucleotide exchange renders Asp-11 mutant actins resistant to depolymerizing activity of cofilin, leading to dominant toxicity in vivo

scientific article published on 3 December 2012

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23212920%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Rapid nucleotide exchange renders Asp-11 mutant actins resistant to depolymerizing activity of cofilin, leading to dominant toxicity in vivo (English)

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19 February 2020

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19 February 2020

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19 February 2020

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19 February 2020

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Nobuhisa Umeki

1

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19 February 2020

Taro Q P Noguchi

3

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19 February 2020

Kiyotaka Tokuraku

4

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19 February 2020

Kohji Ito

6

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19 February 2020

Taro Q P Uyeda

8

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19 February 2020

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3 December 2012

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19 February 2020

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11

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Journal of Biological Chemistry

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19 February 2020

288

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19 February 2020

3

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19 February 2020

1739-1749

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19 February 2020

De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Normal myofibrillar development followed by progressive sarcomeric disruption with actin accumulations in a mouse Cfl2 knockout demonstrates requirement of cofilin-2 for muscle maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Remodeling of actin filaments by ADF/cofilin proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Direct visualization of secondary structures of F-actin by electron cryomicroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Dynamic regulation of sarcomeric actin filaments in striated muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

A nucleotide state-sensing region on actin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

ADF/cofilin: a functional node in cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Dominant negative mutant actins identified in flightless Drosophila can be classified into three classes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Mutations and polymorphisms of the skeletal muscle alpha-actin gene (ACTA1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Allele-specific effects of human deafness gamma-actin mutations (DFNA20/26) on the actin/cofilin interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

The nature of the globular- to fibrous-actin transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Functional effects of nemaline myopathy mutations on human skeletal alpha-actin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Shared genetic causes of cardiac hypertrophy in children and adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Mutation in the alpha-cardiac actin gene associated with apical hypertrophic cardiomyopathy, left ventricular non-compaction, and septal defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Nemaline myopathy with minicores caused by mutation of the CFL2 gene encoding the skeletal muscle actin-binding protein, cofilin-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Antagonistic effects of cofilin, beryllium fluoride complex, and phalloidin on subdomain 2 and nucleotide-binding cleft in F-actin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Myosin-II-dependent localization and dynamics of F-actin during cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

A mutation in the gamma actin 1 (ACTG1) gene causes autosomal dominant hearing loss (DFNA20/26)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Mutations in the gamma-actin gene (ACTG1) are associated with dominant progressive deafness (DFNA20/26).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Interaction of actin monomers with Acanthamoeba actophorin (ADF/cofilin) and profilin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Actin mutations in dilated cardiomyopathy, a heritable form of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Cofilin changes the twist of F-actin: implications for actin filament dynamics and cellular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Isolation of 88F actin mutants of Drosophila melanogaster and possible alterations in the mutant actin structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Isolation of a yeast essential gene, COF1, that encodes a homologue of mammalian cofilin, a low-M(r) actin-binding and depolymerizing protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Cofilin is an essential component of the yeast cortical cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Identification, characterization, and intracellular distribution of cofilin in Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Actin is the naturally occurring inhibitor of deoxyribonuclease I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Studies on the role of actin's aspartic acid 3 and aspartic acid 11 using oligodeoxynucleotide-directed site-specific mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Atomic model of the actin filament

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Atomic structure of the actin:DNase I complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Site-directed mutagenesis of the yeast actin gene: a test for actin function in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Characterization of actin filament severing by actophorin from Acanthamoeba castellanii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Systematic mutational analysis of the yeast ACT1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

30 September 2017

Control of actin dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

Dynamic properties of actin. Structural changes induced by beryllium fluoride.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

Cofilin, a protein in porcine brain that binds to actin filaments and inhibits their interactions with myosin and tropomyosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

Exchange and release of the bound nucleotide of F-actin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

pH control of actin polymerization by cofilin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

Inhibition of actin polymerization by latrunculin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

Probing the mechanism of ATP hydrolysis on F-actin using vanadate and the structural analogs of phosphate BeF-3 and A1F-4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

Actin microfilament dynamics in locomoting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

Characterisation of missense mutations in the Act88F gene of Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

28 June 2018

Cofilin is required for organization of sarcomeric actin filaments in chicken skeletal muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

21 September 2018

Screening of novel dominant negative mutant actins using glycine targeted scanning identifies G146V actin that cooperatively inhibits cofilin binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

21 September 2018

A novel system for expressing toxic actin mutants in Dictyostelium and purification and characterization of a dominant lethal yeast actin mutant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

21 September 2018

Severing of F-actin by yeast cofilin is pH-independent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

21 September 2018

Cofilin induced conformational changes in F-actin expose subdomain 2 to proteolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548484

21 September 2018

[27] Molecular genetic tools for study of the cytoskeleton in Dictyostelium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404657

21 January 2018

Properties of actin from the fission yeast Schizosaccharomyces pombe and interaction with fission yeast profilin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of turnover of several myofibrillar proteins and critical evaluation of double isotope method

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorimetry study of N-(1-pyrenyl)iodoacetamide-labelled F-actin. Local structural change of actin protomer both on polymerization and on binding of heavy meromyosin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification from starfish eggs of a protein that depolymerizes actin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actin polymerization and ATP hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of the intracellular free ADP concentration by 19F NMR studies of fluorine-labeled yeast phosphoglycerate kinase in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actophorin preferentially binds monomeric ADP-actin over ATP-bound actin: consequences for cell locomotion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the enzymic interactions of the bound nucleotide of the bound nucleotide of the muscle protein actin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on actin. I. The interaction of C14-labeled adenine nucleotides with actin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two mouse cofilin isoforms, muscle-type (MCF) and non-muscle type (NMCF), interact with F-actin with different efficiencies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microscopic analysis of polymerization dynamics with individual actin filaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/23212920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.404657

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23212920%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23212920%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23212920%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

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