(Q36547212)

14 August 2017

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title

Tracking STAT nuclear traffic (English)

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14 August 2017

Nancy C Reich

1

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14 August 2017

Ling Liu

series ordinal

2

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14 August 2017

publication date

1 August 2006

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Nature Reviews Immunology

14 August 2017

published in

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14 August 2017

volume

6

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14 August 2017

issue

8

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14 August 2017

page(s)

602-612

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https://scigraph.springernature.com/pub.10.1038/nri1885

14 August 2017

exact match

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cites work

STATs and gene regulation

1 reference

The Stat family in cytokine signaling

21 January 2018

1 reference

Signaling through the JAK/STAT pathway, recent advances and future challenges

21 January 2018

1 reference

Stats: transcriptional control and biological impact

21 January 2018

1 reference

How cells respond to interferons

21 January 2018

1 reference

Three-dimensional structure of the Stat3beta homodimer bound to DNA

21 January 2018

1 reference

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

21 January 2018

1 reference

Structural bases of unphosphorylated STAT1 association and receptor binding

21 January 2018

1 reference

Structure of the unphosphorylated STAT5a dimer

21 January 2018

1 reference

Preassociation of STAT1 with STAT2 and STAT3 in separate signalling complexes prior to cytokine stimulation

21 January 2018

1 reference

21 January 2018

The Janus kinases (Jaks)

1 reference

The Janus kinase family of protein tyrosine kinases and their role in signaling

21 January 2018

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Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process

21 January 2018

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Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

21 January 2018

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Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation.

21 January 2018

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RANTES and MIP-1alpha activate stats in T cells

21 January 2018

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STAT activation by epidermal growth factor (EGF) and amphiregulin. Requirement for the EGF receptor kinase but not for tyrosine phosphorylation sites or JAK1.

21 January 2018

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ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases

21 January 2018

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In vitro activation of Stat3 by epidermal growth factor receptor kinase

21 January 2018

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Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins

21 January 2018

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Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

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Signal transducer and activator of transcription proteins in leukemias.

21 January 2018

1 reference

21 January 2018

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JAK-STAT signaling activated by Abl oncogenes

21 January 2018

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Functional roles of STAT family proteins: lessons from knockout mice

21 January 2018

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

21 January 2018

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Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

21 January 2018

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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

21 January 2018

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Essential role of Stat6 in IL-4 signalling

21 January 2018

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Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

21 January 2018

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Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation

21 January 2018

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

21 January 2018

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

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21 January 2018

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Silencing STATs: lessons from paramyxovirus interferon evasion

21 January 2018

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The yeast nuclear pore complex: composition, architecture, and transport mechanism

21 January 2018

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21 January 2018

Peering through the Pore

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Nucleocytoplasmic transport

21 January 2018

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Transport into and out of the nucleus

21 January 2018

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Nucleocytoplasmic transport: the soluble phase

21 January 2018

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Mechanisms of Receptor-Mediated Nuclear Import and Nuclear Export

21 January 2018

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Nucleocytoplasmic transport: navigating the channel

21 January 2018

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Translocation through the nuclear pore complex: selectivity and speed by reduction-of-dimensionality

21 January 2018

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Virtual gating and nuclear transport: the hole picture

21 January 2018

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Nuclear targeting sequences--a consensus?

21 January 2018

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Transport between the cell nucleus and the cytoplasm

21 January 2018

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Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence

21 January 2018

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Structure of importin-beta bound to the IBB domain of importin-alpha

21 January 2018

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Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha

21 January 2018

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Determination of the functional domain organization of the importin alpha nuclear import factor

21 January 2018

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Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha

21 January 2018

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Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor

21 January 2018

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Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import

21 January 2018

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Nucleocytoplasmic protein traffic and its significance to cell function

21 January 2018

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Nuclear targeting of proteins: how many different signals?

21 January 2018

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Importin-beta-like nuclear transport receptors

21 January 2018

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Identification of a signal for rapid export of proteins from the nucleus

21 January 2018

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CRM1 is an export receptor for leucine-rich nuclear export signals

21 January 2018

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Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex

21 January 2018

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Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

21 January 2018

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Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

21 January 2018

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A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein tyrosine kinase(s)

21 January 2018

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Tyrosine phosphorylation is required for activation of an alpha interferon-stimulated transcription factor

21 January 2018

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A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

21 January 2018

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Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha

21 January 2018

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Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins

21 January 2018

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STAT2 nuclear trafficking

21 January 2018

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Role of the STAT1-SH2 domain and STAT2 in the activation and nuclear translocation of STAT1

21 January 2018

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Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1

21 January 2018

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Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor.

21 January 2018

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Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha

21 January 2018

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Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein

21 January 2018

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Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs

21 January 2018

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Finding nuclear localization signals

21 January 2018

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Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins

21 January 2018

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Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5

21 January 2018

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Amino-terminal signal transducer and activator of transcription (STAT) domains regulate nuclear translocation and STAT deactivation.

21 January 2018

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Nuclear translocation of IFN-gamma is an intrinsic requirement for its biologic activity and can be driven by a heterologous nuclear localization sequence

21 January 2018

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Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1.

21 January 2018

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Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways

21 January 2018

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How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene

21 January 2018

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Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins

21 January 2018

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Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain

21 January 2018

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Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor

21 January 2018

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Regulation of STAT1 nuclear export by Jak1

21 January 2018

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Identification of a nuclear Stat1 protein tyrosine phosphatase

21 January 2018

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Regulation of gene-activation pathways by PIAS proteins in the immune system

21 January 2018

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Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle

21 January 2018

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The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction

21 January 2018

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Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factors

21 January 2018

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Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3

21 January 2018

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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

21 January 2018

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Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

21 January 2018

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Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level

21 January 2018

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Stat3 and Stat4: members of the family of signal transducers and activators of transcription

21 January 2018

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STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3.

21 January 2018

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Real time analysis of STAT3 nucleocytoplasmic shuttling

21 January 2018

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Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family

21 January 2018

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Adenoviral E1A protein nuclear import is preferentially mediated by importin alpha3 in vitro.

21 January 2018

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RanBP3 contains an unusual nuclear localization signal that is imported preferentially by importin-alpha3.

21 January 2018

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Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements

21 January 2018

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A Novel Sequence in the Coiled-coil Domain of Stat3 Essential for Its Nuclear Translocation

21 January 2018

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Cooperation between STAT3 and c-jun suppresses Fas transcription.

21 January 2018

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Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation

21 January 2018

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Identification of STAT3 as a specific substrate of breast tumor kinase

21 January 2018

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Regulation of Stat3 nuclear export

21 January 2018

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Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner

21 January 2018

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A functional DNA binding domain is required for growth hormone-induced nuclear accumulation of Stat5B.

21 January 2018

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The Dictyostelium prestalk cell inducer DIF regulates nuclear accumulation of a STAT protein by controlling its rate of export from the nucleus

21 January 2018

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The Jak/STAT pathway in model organisms: emerging roles in cell movement

21 January 2018

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Characterization of two mosquito STATs, AaSTAT and CtSTAT. Differential regulation of tyrosine phosphorylation and DNA binding activity by lipopolysaccharide treatment and by Japanese encephalitis virus infection

21 January 2018

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Cloning and developmental expression of STAT5 in Xenopus laevis.

21 January 2018

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C. elegans STAT cooperates with DAF-7/TGF-beta signaling to repress dauer formation

21 January 2018

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Angiotensin II activates Stat5 through Jak2 kinase in cardiac myocytes

21 January 2018

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Immune response in Stat2 knockout mice

31 March 2020

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31 March 2020

The nuclear pore complex

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Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

31 March 2020

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The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1885

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Dimensions Publication ID

14 August 2017

1033925457

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