(Q36549564)

English

Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase

scientific article published on September 1993

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Doherty JB

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Shah SK

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Finke PE

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Dorn CP Jr

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Hagmann WK

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Hale JJ

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Kissinger AL

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Thompson KR

8

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Brause K

9

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Chandler GO

10

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

1 September 1993

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

90

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

18

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

8727-8731

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Human plasma proteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

Proteolysis by neutrophils. Relative importance of cell-substrate contact and oxidative inactivation of proteinase inhibitors in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

Elastase-mediated fibrinogenolysis by chemoattractant-stimulated neutrophils occurs in the presence of physiologic concentrations of antiproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

Isolation, properties, and complete amino acid sequence of human secretory leukocyte protease inhibitor, a potent inhibitor of leukocyte elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

Role of antileukoprotease in the human lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

The discovery and biologic properties of cephalosporin-based inhibitors of PMN elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

PMN elastases: a comparison of the specificity of human isozymes and the enzyme from other species toward substrates and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

30 September 2017

Crystallographic study of a beta-lactam inhibitor complex with elastase at 1.84 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

28 June 2018

Inhibition of human leukocyte elastase. 2. Inhibition by substituted cephalosporin esters and amides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

28 June 2018

Direct assay of A alpha(1-21), a PMN elastase-specific cleavage product of fibrinogen, in the chimpanzee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

28 June 2018

Specificity, stability, and potency of monocyclic beta-lactam inhibitors of human leucocyte elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

28 June 2018

Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47431

28 June 2018

Neutrophil-mediated solubilization of the subendothelial matrix: oxidative and nonoxidative mechanisms of proteolysis used by normal and chronic granulomatous disease phagocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cephalosporin antibiotics can be modified to inhibit human leukocyte elastase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of alpha 1-proteinase inhibitor methoxysuccinyl-Ala-Ala-Pro-Val-chloromethylketone and specific beta-lactam inhibitors in an acute model of human polymorphonuclear leukocyte elastase-induced lung hemorrhage in the hamster

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of proteolysis at the neutrophil-substrate interface by secretory leukoprotease inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human leukocyte elastase. 3. Synthesis and activity of 3'-substituted cephalosporins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

rTNF alpha facilitates human polymorphonuclear leukocyte adherence to fibrinogen matrices with mobilization of specific and tertiary but not azurophilic granule markers

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potency of Antileukoprotease and α1-Antitrypsin to Inhibit Degradation of Fibrinogen by Adherent Polymorphonuclear Leukocytes from Normal Subjects and Patients with Chronic Granulomatous Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human serine proteases by substituted 2-azetidinones

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orally active beta-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones

1 reference

https://pubmed.ncbi.nlm.nih.gov/8378355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.90.18.8727

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1993PNAS...90.8727D

0 references

release_surhjjzzf5celbpy6oz3qxgbry

1 reference

https://api.fatcat.wiki/v0/release/surhjjzzf5celbpy6oz3qxgbry

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

0 references

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