(Q36557149)

English

Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells

scientific article published on 31 July 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

0 references

apoptotic process

1 reference

based on heuristic

inferred from title

cervix uterine cancer

1 reference

based on heuristic

inferred from title

author name string

Jen-Pi Tsai

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Chien-Hsing Lee

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Tsung-Ho Ying

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Chu-Liang Lin

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Chia-Liang Lin

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Jung-Tsung Hsueh

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Yi-Hsien Hsieh

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

31 July 2015

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

30

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

28851-28866

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Dysregulation of autophagy in human follicular lymphoma is independent of overexpression of BCL-2.

1 reference

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30 September 2017

Wogonoside induces autophagy-related apoptosis in human glioblastoma cells

1 reference

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30 September 2017

Clinical potential of bevacizumab in the treatment of metastatic and locally advanced cervical cancer: current evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Licochalcone A suppresses migration and invasion of human hepatocellular carcinoma cells through downregulation of MKK4/JNK via NF-κB mediated urokinase plasminogen activator expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Dendropanoxide induces autophagy through ERK1/2 activation in MG-63 human osteosarcoma cells and autophagy inhibition enhances dendropanoxide-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Regulation of paclitaxel-induced programmed cell death by autophagic induction: A model for cervical cancer

1 reference

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30 September 2017

Isoliquiritigenin induces caspase-dependent apoptosis via downregulation of HPV16 E6 expression in cervical cancer Ca Ski cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Essential role of autophagy in fucoxanthin-induced cytotoxicity to human epithelial cervical cancer HeLa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Apoptosis-related BCL2-family members: Key players in chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Natural products targeting autophagy via the PI3K/Akt/mTOR pathway as anticancer agents.

1 reference

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30 September 2017

Inhibition of mTOR signaling by quercetin in cancer treatment and prevention

1 reference

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30 September 2017

Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells

1 reference

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30 September 2017

Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Licochalcone a inhibits lipopolysaccharide-induced inflammatory response in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Aristolochic acid I induced autophagy extenuates cell apoptosis via ERK 1/2 pathway in renal tubular epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

The role of Atg proteins in autophagosome formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Autophagy as a target for anticancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Licochalcone A inhibits growth of gastric cancer cells by arresting cell cycle progression and inducing apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

A novel sphingosine kinase inhibitor induces autophagy in tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Cathepsin L mediates resveratrol-induced autophagy and apoptotic cell death in cervical cancer cells

1 reference

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30 September 2017

Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: a systematic review and meta-analysis of individual patient data from 18 randomized trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Licochalcone A isolated from licorice suppresses lipopolysaccharide-stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Self-eating and self-killing: crosstalk between autophagy and apoptosis

1 reference

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30 September 2017

Defining the role of mTOR in cancer

1 reference

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30 September 2017

Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways

1 reference

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Tissue transglutaminase inhibits autophagy in pancreatic cancer cells

1 reference

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30 September 2017

Regulation of autophagy by the inositol trisphosphate receptor

1 reference

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30 September 2017

Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death

1 reference

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Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

1 reference

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Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world

1 reference

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30 September 2017

Exploiting the PI3K/AKT pathway for cancer drug discovery

1 reference

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

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30 September 2017

Autophagy: dual roles in life and death?

1 reference

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30 September 2017

LC3 conjugation system in mammalian autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

30 September 2017

Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells

1 reference

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30 September 2017

Phosphoinositide 3-kinase accelerates autophagic cell death during glucose deprivation in the rat cardiomyocyte-derived cell line H9c2.

1 reference

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30 September 2017

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

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Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

1 reference

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Mutational and expressional analyses of ATG5, an autophagy-related gene, in gastrointestinal cancers.

1 reference

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21 September 2018

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

1 reference

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21 September 2018

Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

21 September 2018

Shallot and licorice constituent isoliquiritigenin arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and initiation of the mitochondrial system in human cervical carcinoma HeLa cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4745696

21 September 2018

Life and death partners: apoptosis, autophagy and the cross-talk between them

1 reference

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21 September 2018

Anti-proliferative effect of licochalcone A on vascular smooth muscle cells.

1 reference

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21 September 2018

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

1 reference

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21 September 2018

Suppression of PI3K/mTOR pathway rescues LLC cells from cell death induced by hypoxia

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A controlled trial of a human papillomavirus type 16 vaccine

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21 September 2018

Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells

1 reference

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4 December 2018

Modulation of bcl-2 and cytotoxicity by licochalcone-A, a novel estrogenic flavonoid

1 reference

https://pubmed.ncbi.nlm.nih.gov/26311737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/26311737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/26311737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26311737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of autophagy by p38alpha MAPK

1 reference

https://pubmed.ncbi.nlm.nih.gov/26311737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/26311737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor and antimetastatic effects of licochalcone A in mouse models

1 reference

https://pubmed.ncbi.nlm.nih.gov/26311737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.4767

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

0 references

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