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(Q36564577)
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English
An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ
scientific article published on January 1997
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Statements
instance of
scholarly article
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
title
An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ
(English)
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
author name string
Luo Z
series ordinal
1
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
Diaz B
series ordinal
2
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
Marshall MS
series ordinal
3
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
Avruch J
series ordinal
4
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
language of work or name
English
0 references
publication date
1 January 1997
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
published in
Molecular and Cellular Biology
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
volume
17
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
page(s)
46-53
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stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
issue
1
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
cites work
The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Post-translational modification of H-Ras is required for activation of, but not for association with, B-Raf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Mammalian Ras interacts directly with the serine/threonine kinase Raf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
A phorbol ester binding domain of protein kinase C gamma. Deletion analysis of the Cys2 domain defines a minimal 43-amino acid peptide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
The effector interactions of p21ras
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Zinc finger domains and phorbol ester pharmacophore. Analysis of binding to mutated form of protein kinase C zeta and the vav and c-raf proto-oncogene products
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Raf meets Ras: completing the framework of a signal transduction pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Critical binding and regulatory interactions between Ras and Raf occur through a small, stable N-terminal domain of Raf and specific Ras effector residues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Identification of discrete segments of human Raf-1 kinase critical for high affinity binding to Ha-Ras.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Activation of Raf as a result of recruitment to the plasma membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Two distinct Raf domains mediate interaction with Ras
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Activation of the MAP kinase pathway by the protein kinase raf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Raf-1 activates MAP kinase-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
30 September 2017
Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
28 June 2018
Mitogen regulation of c-Raf-1 protein kinase activity toward mitogen-activated protein kinase-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
28 June 2018
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
28 June 2018
Functional mapping of the N-terminal regulatory domain in the human Raf-1 protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
28 June 2018
Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
28 June 2018
The minimal fragments of c-Raf-1 and NF1 that can suppress v-Ha-Ras-induced malignant phenotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
21 September 2018
Purification and characterization of REKS from Xenopus eggs. Identification of REKS as a Ras-dependent mitogen-activated protein kinase kinase kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
21 September 2018
The farnesyl group of H-Ras facilitates the activation of a soluble upstream activator of mitogen-activated protein kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231728
retrieved
21 September 2018
Identification of the sites of interaction between c-Raf-1 and Ras-GTP
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8972184
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of the 14.3.3 zeta domains important for self-association and Raf binding
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8972184
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8972184
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.17.1.46
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
PMCID
231728
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
PubMed ID
8972184
1 reference
stated in
Q5412157
PMCID
231728
retrieved
15 August 2017
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