(Q36570454)

English

Probing the structure and function of the estrogen receptor ligand binding domain by analysis of mutants with altered transactivation characteristics

scientific article published on August 1997

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Probing the structure and function of the estrogen receptor ligand binding domain by analysis of mutants with altered transactivation characteristics (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1 reference

based on heuristic

inferred from title

author name string

F C Eng

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

H S Lee

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

J Ferrara

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

T M Willson

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

J H White

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

0 references

publication date

1 August 1997

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

17

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

4644-4653

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Control of transcription by steroid hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

The RXR heterodimers and orphan receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

The nuclear receptor superfamily: the second decade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

1 reference

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30 September 2017

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Efficient random mutagenesis method with adjustable mutation frequency by use of PCR and dITP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

A molecular modelling study on the hormone binding site of the estrogen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Defining a minimal estrogen receptor DNA binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Hormone binding and transcription activation by estrogen receptors: analyses using mammalian and yeast systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Structure-function analysis of the hormone binding domain of the human estrogen receptor by region-specific mutagenesis and phenotypic screening in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Insights from the study of animals lacking functional estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Subunit structure of the nonactivated human estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

A transcriptional co-repressor that interacts with nuclear hormone receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Structure and dynamics of the estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

A versatile in vivo and in vitro eukaryotic expression vector for protein engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Zinc fingers: gilt by association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Estrogen receptor localization in the female genital tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Solution structure of the DNA-binding domain of the oestrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Transcription activation by estrogen and progesterone receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Estrogen receptor mutants which do not bind 17 beta-estradiol dimerize and bind to the estrogen response element in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

30 September 2017

Constitutively active human estrogen receptors containing amino acid substitutions for tyrosine 537 in the receptor protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Human estrogen receptor ligand activity inversion mutants: receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Artificial control of nuclear translocation of DNA repair methyltransferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

A structural role for hormone in the thyroid hormone receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Expression and function of the human estrogen receptor in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Studies on the cellular localization and distribution of glucocorticoid receptor and estrogen receptor immunoreactivity in the central nervous system of the rat and their relationship to the monoaminergic and peptidergic neurons of the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

The N-terminal region of the chicken progesterone receptor specifies target gene activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Several regions of human estrogen receptor are involved in the formation of receptor-heat shock protein 90 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Reduced levels of hsp90 compromise steroid receptor action in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

Solution structure of the glucocorticoid receptor DNA-binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

28 June 2018

The human oestrogen receptor functions in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232317

4 December 2018

Hormone-dependent transactivation by estrogen receptor chimeras that do not interact with hsp90. Evidence for transcriptional repressors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A canonical structure for the ligand-binding domain of nuclear receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional domains of the human estrogen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Luciferase reporter gene vectors for analysis of promoters and enhancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human estrogen receptor has transcriptional activator and repressor functions in the absence of ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Powerful dominant negative mutants of the human estrogen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A highly conserved region in the hormone-binding domain of the human estrogen receptor functions as an efficient transactivation domain in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/9234721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.17.8.4644

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

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