(Q36571458)

15 August 2017

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title

Statins and the endothelium (English)

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15 August 2017

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Masaaki Ii

1

1 reference

PubMed ID

16920035

15 August 2017

Douglas W Losordo

series ordinal

2

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15 August 2017

21 June 2006

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15 August 2017

Vascular Pharmacology

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15 August 2017

46

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15 August 2017

1

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15 August 2017

1-9

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Statin therapy is associated with improved patency of autogenous infrainguinal bypass grafts

15 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheroma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Enhancement of ischemia-induced angiogenesis by eNOS overexpression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Isolation of putative progenitor endothelial cells for angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (pravastatin) inhibits endothelial cell proliferation dependent on G1 cell cycle arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

7 January 2021

The acute phase response

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Overexpression of endothelial nitric oxide synthase increases skeletal muscle blood flow and oxygenation in severe rat hind limb ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Intensive versus moderate lipid lowering with statins after acute coronary syndromes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Mobilized Endothelial Progenitor Cells by Granulocyte-Macrophage Colony-Stimulating Factor Accelerate Reendothelialization and Reduce Vascular Inflammation After Intravascular Radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statins and cancer prevention

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Gene therapy for cardiovascular angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Very low-density lipoprotein activates nuclear factor-kappaB in endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Effect of atherosclerosis on endothelium-dependent inhibition of platelet activation in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Beta4 integrin is involved in statin-induced endothelial cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Long-term results after microvascular decompression in essential hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Bone Marrow Monocyte Lineage Cells Adhere on Injured Endothelium in a Monocyte Chemoattractant Protein-1–Dependent Manner and Accelerate Reendothelialization as Endothelial Progenitor Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Vascular Endothelial Growth Factor Regulates Reendothelialization and Neointima Formation in a Mouse Model of Arterial Injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Relation between endothelial dysfunction and the acute coronary syndrome: implications for therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Serum cholesterol in young men and subsequent cardiovascular disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Estradiol accelerates functional endothelial recovery after arterial injury.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

In vivo blockade of tumor necrosis factor-alpha accelerates functional endothelial recovery after balloon angioplasty.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Nitric oxide: an endogenous modulator of leukocyte adhesion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statin therapy for cardiac hypertrophy and heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Modified low density lipoproteins activate human macrophages to secrete immunoreactive endothelin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Simvastatin enhances the regeneration of endothelial cells via VEGF secretion in injured arteries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Angiogenesis Induced by Endothelial Nitric Oxide Synthase Gene Through Vascular Endothelial Growth Factor Expression in a Rat Hindlimb Ischemia Model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statin-induced apoptosis of vascular endothelial cells is blocked by dexamethasone.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Short-term statin therapy improves cardiac function and symptoms in patients with idiopathic dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Catheter-based prostacyclin synthase gene transfer prevents in-stent restenosis in rabbit atheromatous arteries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Cerivastatin ameliorates high insulin-enhanced neutrophil–endothelial cell adhesion and endothelial intercellular adhesion molecule-1 expression by inhibiting mitogen-activated protein kinase activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Impaired endothelium-dependent vasodilation in patients with essential hypertension. Evidence that nitric oxide abnormality is not localized to a single signal transduction pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors interfere with angiogenesis by inhibiting the geranylgeranylation of RhoA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statins and cardiovascular diseases: the multiple effects of lipid-lowering therapy by statins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Simvastatin reduces the expression of adhesion molecules in circulating monocytes from hypercholesterolemic patients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Low-level endotoxin induces potent inflammatory activation of human blood vessels: inhibition by statins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Mechanisms of angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statin therapy in patients with coronary artery disease improves the impaired endothelial progenitor cell differentiation into cardiomyogenic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Role of macrophage-derived histamine in atherosclerosis-- chronic participation in the inflammatory response --.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statins prevent oxidized low-density lipoprotein- and lysophosphatidylcholine-induced proliferation of human endothelial cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Lovastatin-stimulated superinduction of E-selectin, ICAM-1 and VCAM-1 in TNF-alpha activated human vascular endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Reversal of experimental diabetic neuropathy by VEGF gene transfer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes: the MIRACL study: a randomized controlled trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

HMG-CoA reductase inhibitors promote cholesterol-dependent Akt/PKB translocation to membrane domains in endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Estrogen increases bone marrow-derived endothelial progenitor cell production and diminishes neointima formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Systemic lupus erythematosus presented as non-inflammatory necrotizing vasculopathy-induced ischemic glomerulopathy and small vessels-related ischemic cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Single LDL apheresis improves endothelium-dependent vasodilatation in hypercholesterolemic humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Novel molecular therapeutic approach to cardiovascular disease based on hepatocyte growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Double-edged role of statins in angiogenesis signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Inhibition of endothelial cell migration by cerivastatin, an HMG-CoA reductase inhibitor: contribution to its anti-angiogenic effect

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Cerivastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase, inhibits endothelial cell proliferation induced by angiogenic factors in vitro and angiogenesis in in vivo models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

3-hydroxy-3-methylglutaryl coenzyme A reductase-independent inhibition of CD40 expression by atorvastatin in human endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Local gene transfer of phVEGF-2 plasmid by gene-eluting stents: an alternative strategy for inhibition of restenosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Rosiglitazone facilitates angiogenic progenitor cell differentiation toward endothelial lineage: a new paradigm in glitazone pleiotropy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Involvement of tyrosine phosphorylation in endothelial adhesion molecule induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Statins have biphasic effects on angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Intense microvascular constriction after angioplasty of acute thrombotic coronary arterial lesions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Foot microcirculation and blood rheology in diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

Impaired microcirculation in heart failure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.06.012

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VPH.2006.06.012

1 reference

15 August 2017

1 reference

PubMed ID

16920035