(Q36571464)

English

Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-L-carnitine: effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells.

scientific article published on 17 November 2007

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scholarly article

1 reference

Europe PubMed Central

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29 December 2019

Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-L-carnitine: effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells (English)

1 reference

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29 December 2019

peripheral neuropathy

1 reference

based on heuristic

inferred from title

Sarah Jane Louise Flatters

2

1 reference

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29 December 2019

author name string

Hai Wei Jin

1

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29 December 2019

Wen Hua Xiao

3

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29 December 2019

Howard L Mulhern

4

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29 December 2019

Gary J Bennett

5

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29 December 2019

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17 November 2007

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29 December 2019

Experimental Neurology

1 reference

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29 December 2019

210

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29 December 2019

1

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29 December 2019

229-237

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Europe PubMed Central

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29 December 2019

Chemotherapy-evoked neuropathic pain: Abnormal spontaneous discharge in A-fiber and C-fiber primary afferent neurons and its suppression by acetyl-L-carnitine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

A double-blind, parallel-group, placebo-controlled, multicentre study of acetyl L-carnitine in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Co-regulation of dopamine D1 receptor and uncoupling protein-2 expression in 3-nitropropionic acid-induced neurotoxicity: neuroprotective role of L-carnitine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Paclitaxel- and vincristine-evoked painful peripheral neuropathies: loss of epidermal innervation and activation of Langerhans cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Critical dependence of neurons on mitochondrial dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Dysregulation of cellular calcium homeostasis in chemotherapy-evoked painful peripheral neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Studies of peripheral sensory nerves in paclitaxel-induced painful peripheral neuropathy: evidence for mitochondrial dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Acetyl-L-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

EFNS guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Effects of metabolic modifiers such as carnitines, coenzyme Q10, and PUFAs against different forms of neurotoxic insults: metabolic inhibitors, MPTP, and methamphetamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Mechanisms of ischemic neuroprotection by acetyl-L-carnitine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Acetyl-l-carnitine: a pathogenesis based treatment for HIV-associated antiretroviral toxic neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Acetyl-l-carnitine induces muscarinic antinocieption in mice and rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Paclitaxel induces release of cytochrome c from mitochondria isolated from human neuroblastoma cells'

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Effect on the peripheral nervous system of the short-term intravenous administration of paclitaxel in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Ethical guidelines for investigations of experimental pain in conscious animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

30 September 2017

Mitochondrial oxidative metabolism in motor neuron degeneration (mnd) mouse central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

28 June 2018

Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

28 June 2018

Acetyl-L-carnitine treatment increases nerve growth factor levels and choline acetyltransferase activity in the central nervous system of aged rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

28 June 2018

Acetyl-L-carnitine restores choline acetyltransferase activity in the hippocampus of rats with partial unilateral fimbria-fornix transection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

28 June 2018

Structure of tubulin at 6.5 A and location of the taxol-binding site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

28 June 2018

Experimental peripheral neuropathy induced in adult rats by repeated intraperitoneal administration of taxol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

28 June 2018

Sensory innervation of periodontal ligament of rat molars consists of unencapsulated Ruffini-like mechanoreceptors and free nerve endings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

28 June 2018

Levocarnitine acetyl promotes the regeneration of peripheral sensory axons and reduces the hypertrophy of axotomized spinal cord motoneurons in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

28 June 2018

L-carnitine protects neurons from 1-methyl-4-phenylpyridinium-induced neuronal apoptosis in rat forebrain culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Protective role of carnitine ester against radiation-induced oxidative stress in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Acetyl-L-carnitine modulates bleomycin-induced oxidative stress and energy depletion in lung tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Intraepidermal nerve fiber density in rat foot pad: neuropathologic-neurophysiologic correlation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Chemotherapy-induced allodinia: neuroprotective effect of acetyl-L-carnitine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Ethosuximide reverses paclitaxel- and vincristine-induced painful peripheral neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Primary sensory neuronal rescue with systemic acetyl-l-carnitine following peripheral axotomy. A dose-response analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy. A long-term, randomised, double-blind, placebo-controlled study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Systemic acetyl-L-carnitine eliminates sensory neuronal loss after peripheral axotomy: a new clinical approach in the management of peripheral nerve trauma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Direct effect of Taxol on free radical formation and mitochondrial permeability transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Description of a short-term Taxol-induced nociceptive neuropathy in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Fine structure of subepithelial "free" and corpuscular trigeminal nerve endings in anterior hard palate of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323600

21 September 2018

Sensory neurons and their supporting cells located in the trigeminal, thoracic and lumbar ganglia differentially express markers of injury following intravenous administration of paclitaxel in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Counteraction on experimentally induced diabetic neuropathy by levocarnitine acetyl

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed acetyl-L-carnitine administration and its effect on sensory neuronal rescue after peripheral nerve injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetyl-L-carnitine corrects the altered peripheral nerve function of experimental diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective actions of L-carnitine and acetyl-L-carnitine on the neurotoxicity evoked by mitochondrial uncoupling or inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotherapy-evoked painful peripheral neuropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tubulin is an inherent component of mitochondrial membranes that interacts with the voltage-dependent anion channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological characterization of Taxol-induced large-fiber sensory neuropathy in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional reconstruction of scleral cold thermoreceptors of the cat eye

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta-fiber nociceptive primary afferent neurons: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetyl-L-carnitine reduces the age-dependent loss of glucocorticoid receptors in the rat hippocampus: an autoradiographic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of levo-acetylcarnitine on second motoneuron survival after axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of paclitaxel within the nervous system of the rat after repeated intravenous administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria in fine afferent nerve fibres of the knee joint in the cat: a quantitative electron-microscopical examination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubule-active drugs suppress the closure of the permeability transition pore in tumour mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LONG-CHAIN CARNITINE ACYLTRANSFERASE AND THE ROLE OF ACYLCARNITINE DERIVATIVES IN THE CATALYTIC INCREASE OF FATTY ACID OXIDATION INDUCED BY CARNITINE

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid-induced Ca(2+)-dependent uncoupling and activation of external pathway of NADH oxidation are coupled to cyclosporin A-sensitive mitochondrial permeability transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/18078936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EXPNEUROL.2007.11.001

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078936%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078936%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078936%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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