(Q36579431)

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Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage

scientific article published on 11 December 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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author name string

Sufang Zhang

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Yajing Zhou

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ali Sarkeshik

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

John R Yates

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Timothy M Thomson

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Zhongtao Zhang

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ernest Y C Lee

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Marietta Y W T Lee

8

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Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

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publication date

11 December 2012

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Europe PubMed Central

PMC publication ID

15 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

15 August 2017

288

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

2941-2950

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Regulation of human DNA polymerase delta in the cellular responses to DNA damage

1 reference

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9 September 2017

Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage

1 reference

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9 September 2017

Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation

1 reference

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9 September 2017

Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation

1 reference

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9 September 2017

Close encounters of the RNF8th kind: when chromatin meets DNA repair

1 reference

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9 September 2017

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

1 reference

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9 September 2017

Y-family DNA polymerases and their role in tolerance of cellular DNA damage.

1 reference

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Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions

1 reference

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9 September 2017

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair

1 reference

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Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor

1 reference

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Mitotic spindle proteomics in Chinese hamster ovary cells

1 reference

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9 September 2017

DNA damage response and transcription

1 reference

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9 September 2017

DNA polymerases and repair synthesis in NER in human cells

1 reference

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9 September 2017

The cullin protein family

1 reference

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9 September 2017

Ubiquitination of PCNA and its essential role in eukaryotic translesion synthesis

1 reference

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9 September 2017

Assembly and function of DNA double-strand break repair foci in mammalian cells

1 reference

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9 September 2017

Replication factor C recruits DNA polymerase delta to sites of nucleotide excision repair but is not required for PCNA recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561517

9 September 2017

The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561517

9 September 2017

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells

1 reference

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9 September 2017

PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase delta

1 reference

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9 September 2017

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

1 reference

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9 September 2017

Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561517

9 September 2017

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561517

9 September 2017

DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561517

9 September 2017

Histone ubiquitination associates with BRCA1-dependent DNA damage response

1 reference

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9 September 2017

PCNA is ubiquitinated by RNF8

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561517

9 September 2017

Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly

1 reference

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FHA-RING ubiquitin ligases in cell division cycle control

1 reference

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New players in the BRCA1-mediated DNA damage responsive pathway

1 reference

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9 September 2017

Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA.

1 reference

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The DNA damage response: ten years after

1 reference

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Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step.

1 reference

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9 September 2017

Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

1 reference

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9 September 2017

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

1 reference

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9 September 2017

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

1 reference

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9 September 2017

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

1 reference

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9 September 2017

Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cells

1 reference

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9 September 2017

A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta

1 reference

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9 September 2017

Functional roles of p12, the fourth subunit of human DNA polymerase delta

1 reference

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DNA polymerases that propagate the eukaryotic DNA replication fork

1 reference

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Reconstitution and characterization of the human DNA polymerase delta four-subunit holoenzyme

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N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8

1 reference

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Isolation, tissue expression, and chromosomal assignment of a novel human gene which encodes a protein with RING finger motif

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Purification of deoxyribonucleic acid polymerase delta from calf thymus: partial characterization of physical properties

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Further studies on calf thymus DNA polymerase delta purified to homogeneity by a new procedure

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A new mammalian DNA polymerase with 3' to 5' exonuclease activity: DNA polymerase delta

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DNA polymerase delta is preferentially recruited during homologous recombination to promote heteroduplex DNA extension

1 reference

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The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation

1 reference

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21 January 2018

Expression, purification, and properties of the Ubc4/5 family of E2 enzymes.

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UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathways.

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21 January 2018

Ubiquitin transfer from the E2 perspective: why is UbcH5 so promiscuous?

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of mitotic exit by the RNF8 ubiquitin ligase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23233665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.423392

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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