(Q36579764)

English

Regulatory function of the P295-T311 motif of the estrogen receptor alpha - does proteasomal degradation of the receptor induce emergence of peptides implicated in estrogenic responses?

scientific article published on 18 April 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

15 August 2017

1 reference

Europe PubMed Central

Regulatory function of the P295-T311 motif of the estrogen receptor alpha - does proteasomal degradation of the receptor induce emergence of peptides implicated in estrogenic responses? (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

0 references

author name string

Dominique Gallo

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Iman Haddad

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Guy Laurent

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Joëlle Vinh

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Françoise Jacquemotte

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Yves Jacquot

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Guy Leclercq

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

publication date

18 April 2008

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Nuclear Receptor Signaling

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

e007

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ligand-dependent transcription of estrogen receptor alpha is mediated by the ubiquitin ligase EFP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase

1 reference

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9 September 2017

Functional interactions between calmodulin and estrogen receptor-alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Estrogen receptor alpha: impact of ligands on intracellular shuttling and turnover rate in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Transcription in four dimensions: nuclear receptor-directed initiation of gene expression

1 reference

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9 September 2017

Intracellular localization and nucleocytoplasmic trafficking of steroid receptors: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland

1 reference

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9 September 2017

Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor {alpha} by the proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Estrogen receptor mutations in human disease

1 reference

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9 September 2017

Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions

1 reference

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9 September 2017

Novel selective inhibitors of the interaction of individual nuclear hormone receptors with a mutually shared steroid receptor coactivator 2.

1 reference

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9 September 2017

Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Regulation of estrogen receptor nuclear export by ligand-induced and p38-mediated receptor phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Receptorphin: a conserved peptide derived from the sequence of the opioid receptor, with opioid displacement activity and potent antiproliferative actions in tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Estrogen receptors and proliferation markers in primary and recurrent breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

MDM2 enhances the function of estrogen receptor alpha in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Proteasome involvement in agonist-induced down-regulation of mu and delta opioid receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Peptide antagonists of the human estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Gene Regulation for Higher Cells: A Theory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

9 September 2017

Trophic effect in MCF-7 cells of ERalpha17p, a peptide corresponding to a platform regulatory motif of the estrogen receptor alpha--underlying mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Effect of nuclear export inhibition on estrogen receptor regulation in breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Differential regulation of estrogen receptor alpha turnover and transactivation by Mdm2 and stress-inducing agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

The hinge region regulates DNA binding, nuclear translocation, and transactivation of the androgen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Calmodulin-independent, agonistic properties of a peptide containing the calmodulin binding site of estrogen receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

E6AP and calmodulin reciprocally regulate estrogen receptor stability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Role of the proteasome in the regulation of estrogen receptor alpha turnover and function in MCF-7 breast carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Inhibiting proteasomal proteolysis sustains estrogen receptor-alpha activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Calmodulin enhances the stability of the estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Calmodulin is essential for estrogen receptor interaction with its motif and activation of responsive promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Identification of a third autonomous activation domain within the human estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

A one minute pulse of estradiol to MCF-7 breast cancer cells changes estrogen receptor binding properties and commits cells to induce estrogenic responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

Estrogen and antiestrogen interaction with estrogen receptor of MCF-7 cells--relationship between processing and estrogenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

30 September 2017

CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

28 June 2018

Calmodulin regulates the transcriptional activity of estrogen receptors. Selective inhibition of calmodulin function in subcellular compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

28 June 2018

Identification of cysteine 530 as the covalent attachment site of an affinity-labeling estrogen (ketononestrol aziridine) and antiestrogen (tamoxifen aziridine) in the human estrogen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

28 June 2018

Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

28 June 2018

Distribution plasticity of the human estrogen receptor alpha in live cells: distinct imaging of consecutively expressed receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

20 September 2018

Potent inhibitors of LXXLL-based protein-protein interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

20 September 2018

Design, synthesis, and in vitro biological evaluation of small molecule inhibitors of estrogen receptor alpha coactivator binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

20 September 2018

Thyroid hormone is an inhibitor of estrogen-induced degradation of estrogen receptor-alpha protein: estrogen-dependent proteolysis is not essential for receptor transactivation function in the pituitary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

20 September 2018

The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

20 September 2018

Dynamic shuttling and intranuclear mobility of nuclear hormone receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

20 September 2018

Calmodulin is a selective modulator of estrogen receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

20 September 2018

Analysis of the structural core of the human estrogen receptor ligand binding domain by selective proteolysis/mass spectrometric analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329824

20 September 2018

In VitroInteraction of Estradiol Receptor with Ca2+-Calmodulin

1 reference

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4 December 2018

Molecular biology. Little molecules with big goals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptor alpha--identification by a modeling approach of a potential polyproline II recognizing domain within the AF-2 region of the receptor that would play a role of prime importance in its mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA1 control of steroid receptor ubiquitination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A hypersensitive estrogen receptor-alpha mutation in premalignant breast lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of an estrogen receptor form devoid of estrogen binding ability in MCF-7 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen aziridines: effective inactivators of the estrogen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient and highly selective covalent labeling of the estrogen receptor with [3H]tamoxifen aziridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estradiol-induced down-regulation of estrogen receptor. Effect of various modulators of protein synthesis and expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A highly conserved region in the hormone-binding domain of the human estrogen receptor functions as an efficient transactivation domain in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of estradiol and DNA binding to estrogen receptor upon association with calmodulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogenic and antiestrogenic regulation of the half-life of covalently labeled estrogen receptor in MCF-7 breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18432312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1621/NRS.06007

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

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