(Q36581573)

15 August 2017

Functional analysis suggests unexpected role for conserved active-site residue in enzyme of known structure (English)

1 reference

15 August 2017

Schimmell P

1

1 reference

PMC publication ID

47541

15 August 2017

language of work or name

English

0 references

publication date

1 October 1993

1 reference

Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

90

1 reference

15 August 2017

20

1 reference

15 August 2017

9235-9236

1 reference

Structure-based discovery of inhibitors of thymidylate synthase

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Asparagine 229 in thymidylate synthase contributes to, but is not essential for, catalysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Atomic structure of thymidylate synthase: target for rational drug design

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Asn177 in Escherichia coli thymidylate synthase is a major determinant of pyrimidine specificity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Mutation of asparagine 229 to aspartate in thymidylate synthase converts the enzyme to a deoxycytidylate methylase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Probing the structure and mechanism of Ras protein with an expanded genetic code

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Exclusion of 2'-deoxycytidine 5'-monophosphate by asparagine 229 of thymidylate synthase

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Saturation site-directed mutagenesis of thymidylate synthase.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47541

Crystal structure of Escherichia coli thymidylate synthase containing bound 5-fluoro-2'-deoxyuridylate and 10-propargyl-5,8-dideazafolate

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8415683

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.90.20.9235

1 reference

15 August 2017

0 references

1 reference

PMC publication ID

47541

15 August 2017

PubMed publication ID

8415683

1 reference

PMC publication ID

47541