(Q36584924)

English

A randomized double blind, placebo controlled phase 2 trial of BIIL 284 BS (an LTB4 receptor antagonist) for the treatment of lung disease in children and adults with cystic fibrosis

scientific article published on 17 January 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

A randomized double blind, placebo controlled phase 2 trial of BIIL 284 BS (an LTB4 receptor antagonist) for the treatment of lung disease in children and adults with cystic fibrosis (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

phase II clinical trial

0 references

0 references

cystic fibrosis

0 references

author name string

M W Konstan

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

G Döring

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

S L Heltshe

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

L C Lands

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

K A Hilliard

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

P Koker

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

S Bhattacharya

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

A Staab

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

A Hamilton

9

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Investigators and Coordinators of BI Trial 543.45

10

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

publication date

17 January 2014

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Journal of Cystic Fibrosis

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

148-155

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ibuprofen therapy for cystic fibrosis lung disease: revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Clinical use of Ibuprofen is associated with slower FEV1 decline in children with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Inflammation and anti-inflammatory therapies for cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Clinical trial of a leucotriene B4 receptor antagonist, BIIL 284, in patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Leukotriene receptor antagonists in children with cystic fibrosis lung disease : anti-inflammatory and clinical effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Early intervention and prevention of lung disease in cystic fibrosis: a European consensus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Inhibition of leukotriene B4-induced CD11B/CD18 (Mac-1) expression by BIIL 284, a new long acting LTB4 receptor antagonist, in patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Mucosal factors inducing neutrophil movement in ulcerative colitis: the role of interleukin 8 and leukotriene B4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Sputum tumour necrosis factor-alpha and leukotriene concentrations in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Standardization of Spirometry, 1994 Update. American Thoracic Society

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Changes in the normal maximal expiratory flow-volume curve with growth and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Detection of sputum eicosanoids in cystic fibrosis and in normal saliva by bioassay and radioimmunoassay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

Relationship between leukotriene B4 and immunological parameters in rheumatoid synovial fluids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

9 September 2017

In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B(4) receptor antagonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

30 September 2017

Leukotrienes, LTC4 and LTB4, in bronchoalveolar lavage in bronchial asthma and other respiratory diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

30 September 2017

Induction of inflammatory mediators (histamine and leukotrienes) from rat peritoneal mast cells and human granulocytes by Pseudomonas aeruginosa strains from burn patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

30 September 2017

Effect of high-dose ibuprofen in patients with cystic fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

28 June 2018

Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

28 June 2018

Increased leukotrienes in exhaled breath condensate in childhood asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

20 September 2018

Current understanding of the inflammatory process in cystic fibrosis: onset and etiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

20 September 2018

Pulmonary function between 6 and 18 years of age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

20 September 2018

Identification of leukotrienes in the sputum of patients with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755340

21 October 2018

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24440167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sputum cysteinyl‐leukotriene levels correlate with the severity of pulmonary disease in children with cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24440167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eicosapentaenoic acid in cystic fibrosis: evidence of a pathogenetic role for leukotriene B4

1 reference

https://pubmed.ncbi.nlm.nih.gov/24440167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukotriene B4 markedly elevated in the epithelial lining fluid of patients with cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24440167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cystic fibrosis lung inflammation: early, sustained, and severe

1 reference

https://pubmed.ncbi.nlm.nih.gov/24440167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapies aimed at airway inflammation in cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24440167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-dose ibuprofen in cystic fibrosis: Canadian safety and effectiveness trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/24440167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JCF.2013.12.009

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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