(Q36587768)

English

Activated NF-κB in bone marrow mesenchymal stem cells from systemic lupus erythematosus patients inhibits osteogenic differentiation through downregulating Smad signaling.

scientific article published on 10 October 2012

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22897816%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Activated NF-κB in bone marrow mesenchymal stem cells from systemic lupus erythematosus patients inhibits osteogenic differentiation through downregulating Smad signaling (English)

1 reference

Europe PubMed Central

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11 February 2020

0 references

mesenchymal stem cell

1 reference

based on heuristic

inferred from title

lupus erythematosus

1 reference

based on heuristic

inferred from title

systemic lupus erythematosus

1 reference

based on heuristic

inferred from title

8

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11 February 2020

author name string

Yu Tang

1

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11 February 2020

Hao Xie

2

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11 February 2020

Jinyun Chen

3

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11 February 2020

Linyu Geng

4

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11 February 2020

Haifeng Chen

5

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11 February 2020

Xia Li

6

1 reference

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11 February 2020

Yayi Hou

7

1 reference

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11 February 2020

Songtao Shi

9

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11 February 2020

Xiaofeng Zeng

10

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11 February 2020

Lingyun Sun

11

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11 February 2020

publication date

10 October 2012

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11 February 2020

Stem Cells and Development

1 reference

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11 February 2020

22

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11 February 2020

4

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Europe PubMed Central

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11 February 2020

668-678

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22897816%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Tumor necrosis factor alpha represses bone morphogenetic protein (BMP) signaling by interfering with the DNA binding of Smads through the activation of NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

BMP-2 promotes differentiation of osteoblasts and chondroblasts in Runx2-deficient cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Bone morphogenetic protein signal transduction in bone

1 reference

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9 September 2017

Genomic analysis of anti-hepatitis B virus (HBV) activity by small interfering RNA and lamivudine in stable HBV-producing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Bone morphogenetic protein type IA receptor signaling regulates postnatal osteoblast function and bone remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Tumor necrosis factor-alpha: molecular and cellular mechanisms in skeletal pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

SLE - Complex cytokine effects in a complex autoimmune disease: tumor necrosis factor in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Clinical review 151: The role of parathyroid hormone in the pathogenesis of glucocorticoid-induced osteoporosis: a re-examination of the evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

The role of growth factors in the repair of bone. Biology and clinical applications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

RANK-L and RANK: T cells, bone loss, and mammalian evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Mice lacking Bmp6 function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Bone morphogenetic proteins: an unconventional approach to isolation of first mammalian morphogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Marrow stromal cells as stem cells for nonhematopoietic tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Role of cytokines in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

The 1982 revised criteria for the classification of systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

9 September 2017

Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

30 September 2017

Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels

1 reference

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30 September 2017

TNF-alpha inhibits BMP-induced osteoblast differentiation through activating SAPK/JNK signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

30 September 2017

Methotrexate (MTX) inhibits osteoblastic differentiation in vitro: possible mechanism of MTX osteopathy.

1 reference

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30 September 2017

Inhibition of osteoblast differentiation by tumor necrosis factor-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

30 September 2017

NF-kappaB activation stimulates osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue by increasing TAZ expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

28 June 2018

Gene expression profiling of glucocorticoid-inhibited osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

28 June 2018

Interleukin-1 beta enhances and tumor necrosis factor-alpha inhibits bone morphogenetic protein-2-induced alkaline phosphatase activity in MC3T3-E1 osteoblastic cells

1 reference

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28 June 2018

Loss of trabecular bone mineral density in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

28 June 2018

Estrogen inhibits release of tumor necrosis factor from peripheral blood mononuclear cells in postmenopausal women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

28 June 2018

Sequential induction of marrow stromal cells by FGF2 and BMP2 improves their growth and differentiation potential in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

20 September 2018

Estrogen and glucocorticoid regulate osteoblast differentiation through the interaction of bone morphogenetic protein-2 and tumor necrosis factor-alpha in C2C12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

20 September 2018

Defective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

20 September 2018

Insights into mesenchymal stem cell aging: involvement of antioxidant defense and actin cytoskeleton.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

20 September 2018

Heterogeneity of multipotent mesenchymal stromal cells: from stromal cells to stem cells and vice versa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

20 September 2018

TNFalpha promotes osteogenic differentiation of human mesenchymal stem cells by triggering the NF-kappaB signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

20 September 2018

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

20 September 2018

Enhancement of osteoblastic differentiation of mesenchymal stromal cells cultured by selective combination of bone morphogenetic protein-2 (BMP-2) and fibroblast growth factor-2 (FGF-2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564481

20 September 2018

Elevated tumor necrosis factor-alpha suppresses TAZ expression and impairs osteogenic potential of Flk-1+ mesenchymal stem cells in patients with multiple myeloma.

1 reference

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20 September 2018

RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis.

1 reference

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20 September 2018

Enhanced apoptosis and senescence of bone-marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of osteoblasts in hormonal control of bone resorption - a hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired carboxylation of osteocalcin in warfarin-treated patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Derivation of the SLEDAI

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Musculoskeletal complications of systemic lupus erythematosus in the Hopkins Lupus Cohort: an update

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour necrosis factor alpha and its soluble receptors parallel clinical disease and autoimmune activity in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: down-regulation by glucocorticoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of bone mass in systemic lupus erythematosus: a cross sectional study on premenopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormality of bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22897816

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/SCD.2012.0226

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22897816%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22897816%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22897816%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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