(Q36592378)

15 August 2017

1 reference

title

Bleomycin--mode of action with particular reference to the cell cycle (English)

1 reference

15 August 2017

Bleomycin—mode of action with particular reference to the cell cycle (English)

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

27 August 2023

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https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

27 August 2023

author name string

P. R. Twentyman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6201934

27 August 2023

language of work or name

1 reference

1 January 1983

1 reference

full work available at URL

15 August 2017

https://api.elsevier.com/content/article/PII:0163725883900220?httpAccept=text/xml

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https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

https://api.elsevier.com/content/article/PII:0163725883900220?httpAccept=text/plain

27 August 2023

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Pharmacology & Therapeutics

27 August 2023

published in

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15 August 2017

23

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15 August 2017

3

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15 August 2017

417-441

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Natural and artificial bleomycins: chemistry and antitumor activities

15 August 2017

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/citations/10.1351/PAC197128040665

Isolation and preliminary characterization of bleomycin-resistant mutants from Chinese hamster ovary cells

1

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Control of permeation of bleomycin A2 by polyene antibiotics in cultured Chinese hamster cells

27 August 2023

2

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin-resistant cells contain increased bleomycin-hydrolase activities

27 August 2023

3

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Iron·bleomycin·DNA·system evidence of a long-lived bleomycin·iron·oxygen intermediate

27 August 2023

4

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Pulse cytophotometric analysis of cell cycle perturbation with bleomycin in vitro

27 August 2023

8

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Cell cycle phase recovery from bleomycin-induced potentially lethal damage

27 August 2023

10

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Response of mammalian cells following treatment with bleomycin and 1,3-bis(2-chloroethyl)-1-nitrosourea during plateau phase

27 August 2023

12

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin as a possible synchronizing agent for human tumor cells in vivo

27 August 2023

13

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Studies on recovery from chemically induced damage in mammalian cells

27 August 2023

14

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https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Action of actinomycin D, bleomycin and x rays on HeLa cells

27 August 2023

16

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The effect of bleomycin and radiation in combination on bacteria and mammalian cells in culture

27 August 2023

17

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https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Cytogenetic effects of bleomycin therapy in man

27 August 2023

18

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https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Isolation and characterization of bleomycin-resistant clones of CHO cells

27 August 2023

19

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Effects of arabinofuranosylcytosine on the DNA synthesis of mammalian cells treated with bleomycin

27 August 2023

21

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https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Effects of bleomycin on mouse bone-marrow stem cells

27 August 2023

22

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https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Mechanism of bleomycin action: studies

27 August 2023

24

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https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Molecular interactions of the combined effects of bleomycin and x-rays on mammalian cell survival

27 August 2023

26

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The significance of DNA damage in the cell cycle sensitivity of Chinese hamster ovary cells to bleomycin

27 August 2023

30

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Correlation between cell enlargement and nucleic acid and protein content of HeLa cells in unbalanced growth produced by inhibitors of DNA synthesis

27 August 2023

32

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin pulmonary toxicity

27 August 2023

33

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Intravenous bleomycin infusion as a potential syncronizing agent in human disseminated malignancies: a preliminary report

27 August 2023

34

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Damage of rat liver deoxyribonucleic acid by bleomycin

27 August 2023

35

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Tallysomycin, A Third Generation Bleomycin Analog

27 August 2023

38

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Molecular interactions and cellular changes during the cell cycle

27 August 2023

39

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Ultrastructural study of the effect of bleomycin A2 on the nucleolus and its possibly related cytoplasmic constituents in Novikoff hepatoma cells

27 August 2023

40

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Differential killing efficacy of twenty antitumor drugs on proliferating and nonproliferating human tumor cells

27 August 2023

42

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Strand-scission of HeLa cell deoxyribonucleic acid by bleomycin in vitro and in vivo

27 August 2023

45

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Inhibition of bleomycin-induced DNA breakage by superoxide dismutase

27 August 2023

46

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Interactions of bleomycin with DNA

27 August 2023

49

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Response of solid tumor cells exposed to chemotherapeutic agents in vivo: cell survival after 2- and 24-hour exposure.

27 August 2023

50

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Fragmentation of deoxyribonucleic acid by bleomycin

27 August 2023

51

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin-induced damage in prematurely condensed chromosomes and its relationship to cell cycle progression in CHO cells

27 August 2023

55

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Repair of Bleomycin-damaged DNA by human fibroblasts

27 August 2023

56

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Biological studies on bleomycin A

27 August 2023

57

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin Treatment of the Tumors of Penis and Scrotum

27 August 2023

58

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Current Status of PEP Bleomycin Studies in Japan

27 August 2023

59

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Some effects of bleomycin on the proliferation, maturation time and protein synthesis of hairless mouse epidermis

27 August 2023

60

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Time-dose relationships in combined bleomycin treatment and radiotherapy

27 August 2023

61

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Tallysomycin, a new antitumor antibiotic complex related to bleomycin. I. Production, isolation and properties.

27 August 2023

63

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Induction of concentration-dependent blockade in the G2 phase of the cell cycle by cancer chemotherapeutic agents

27 August 2023

64

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Response of the 9L rat brain tumor to combination treatment with radiation and bleomycin.

27 August 2023

65

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Treatment of malignant lymphomas with bleomycin.

27 August 2023

66

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Classification of Polyene Antibiotics According to Chemical Structure and Biological Effects

27 August 2023

67

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Preferential damage of active chromatin by bleomycin

27 August 2023

70

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin causes release of nucleosomes from chromatin and chromosomes

27 August 2023

71

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

27 August 2023

74

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Copper chelator enhancement of bleomycin cytotoxicity

27 August 2023

75

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

COMB (cyclophosphamide, oncovin, methyl-CCNU, and bleomycin): a four-drug combination in solid tumors

27 August 2023

77

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin-specific fragmentation of double-stranded DNA.

27 August 2023

79

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin fragmentation of duplex DNA occurs as staggered single-strand scissions

27 August 2023

80

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Interactions of the glycopeptide antitumor antibiotics bleomycin and tallysomycin with deoxyribonucleic acid in vitro

27 August 2023

81

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Effects of antineoplastic drugs on plateau-phase cultures of mammalian cells. II. Bleomycin and hydroxyurea.

27 August 2023

82

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Comparison of the response of synchronized Hela cells to talisomycin and bleomycin

27 August 2023

83

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Comparison of DNA damage and single- and double-strand breakage activities on PM-2 DNA by talisomycin and bleomycin analogs

27 August 2023

84

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Comparison of the sequences at specific sites on DNA cleaved by the antitumor antibiotics talisomycin and bleomycin

27 August 2023

85

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin and talisomycin sequence-specific strand scission of DNA: a mechanism of double-strand cleavage

27 August 2023

86

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Phase I and II Study of a New Bleomycin Analog (Pepleomycin)

27 August 2023

87

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Breakage of DNA-membrane complex by bleomycin

27 August 2023

89

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Binding of bleomycin to DNA in bleomycin-sensitive and -resistant rat ascites hepatoma cells

27 August 2023

90

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Ethanol-induced cell sensitization to bleomycin cytotoxicity and the inhibition of recovery from potentially lethal damage

27 August 2023

91

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Potentiation of bleomycin cytotoxicity toward cultured mouse cells by hyperthermia and ethanol

27 August 2023

92

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Selective enhancement of bleomycin cytotoxicity by local anesthetics

27 August 2023

93

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Modulation of bleomycin cytotoxicity

27 August 2023

95

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Influence of pH and length of post-treatment incubation on bleomycin-induced DNA damage

27 August 2023

96

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Action of bleomycin on DNA and RNA

27 August 2023

98

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin inhibition of DNA synthesis in isolated enzyme systems and in intact cell systems

27 August 2023

99

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Decrease of melting temperature and single strand scission of DNA by bleomycin in the presence of 2-mercaptoethanol

27 August 2023

100

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Effects of bleomycin on the cell cycle of Ehrlich ascites carcinoma

27 August 2023

101

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Potentiation of bleomycin by an antifungal polyene, pentamycin, in transformed animal cells

27 August 2023

102

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

A possible role by bithiazoles of bleomycin in causing double-strand scission of DNA

27 August 2023

104

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Antitumour activity and plasma kinetics of bleomycin by continuous and intermittent administration

27 August 2023

107

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Repair of potentially lethal damage in x-irradiated HeLa cells

27 August 2023

108

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The effect of bleomycin on aerated and hypoxic cells in vitro, in combination with irradiation

27 August 2023

110

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Continuous intravenous bleomycin (NSC-125066) therapy with vinblastine (NSC-49842) in stage III testicular neoplasia

27 August 2023

112

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Effect of chelating agents and metal ions on the degradation of DNA by bleomycin

27 August 2023

113

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Effect of bleomycin-radiotherapy combination in management of head and neck squamous cell carcinoma

27 August 2023

114

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Effects of bleomycin and irradiation on euoxic and hypoxic cells

27 August 2023

116

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Relative pulmonary toxicity and antitumor effects of two new bleomycin analogs, pepleomycin and tallysomycin A

27 August 2023

118

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The relationship between DNA and chromosome damage after bleomycin treatment: dose-response measurements

27 August 2023

119

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Terminology in the description of drug-radiation interactions

27 August 2023

121

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Mechanism of action of bleomycin. Studies with the growing culture of bacterial and tumor cells

27 August 2023

122

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Drug sensitivity and some characteristics of a bleomycin-resistant subline of mouse lymphoblastoma L5178Y cells.

27 August 2023

124

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Lethal effect of bleomycin on cultured mouse L cells: comparison between fractionated and continuous treatment

27 August 2023

125

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Bleomycin: Mammalian Cell Lethality and Cellular Basis of Optimal Schedule 2

27 August 2023

127

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Synergism of X-rays and bleomycin on Ehrlich ascites tumour cells

27 August 2023

128

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Interaction of bleomycin with DNA

27 August 2023

129

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Lethal effect of bleomycin on cultured mammalian cells

27 August 2023

132

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Breaks and rejoining of DNA in cultured mammalian cells treated with bleomycin

27 August 2023

133

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Combined effect of X-ray and bleomycin on cultured mammalian cells

27 August 2023

135

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Epidermal cell kinetics in hairless mice after bleomycin. II. Perturbations after multiple doses

27 August 2023

139

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Arrest of Chinese hamster cells in G 2 following treatment with the anti-tumor drug bleomycin

27 August 2023

140

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

A simple, rapid technique for determination of the effects of chemotherapeutic agents on mammalian cell-cycle traverse

27 August 2023

141

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Differential survival of cell subpopulations in spheroids after treatment with bleomycin

27 August 2023

142

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The effect of bleomycin and pentamycin in combination on the survival of EMT6 mouse tumour cells in vitro and in vivo

27 August 2023

143

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

An artefact in clonogenic assays of bleomycin cytotoxicity

27 August 2023

145

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The sensitivity of cells in exponential and stationary phases of growth to bleomycin and to 1,3-bis(2-chloroethyl)-1-nitrosourea

27 August 2023

146

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The sensitivity to bleomycin of spleen colony forming units in the mouse

27 August 2023

147

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The sensitivity to bleomycin of a solid mouse tumour at different stages of growth

27 August 2023

148

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Changes in sensitivity to radiation and to bleomycin occurring during the life history of monolayer cultures of a mouse tumour cell line

27 August 2023

149

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Studies of "potentially lethal damage" in EMT6 mouse tumour cells treated with bleomycin either in vitro or in vivo

27 August 2023

150

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The sensitivity to cytotoxic agents of the EMT6 tumour in vivo. Comparative response of lung nodules in rapid exponential growth and of the solid flank tumour

27 August 2023

151

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The chemical inhibition of PLDR (potentially lethal damage repair) in vitro and in vivo in cancer therapy

27 August 2023

152

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

New antibiotics, bleomycin A and B

27 August 2023

154

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Purification of bleomycins

27 August 2023

155

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

A bleomycin-inactivating enzyme in mouse liver

27 August 2023

157

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Therapy of solid Walker carcinosarcoma 256 with bleomycin after synchronization with hydroxyurea

27 August 2023

159

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

The combined effect of bleomycin and hyperthermia on the adenocarcinoma 284 of the C3H mouse

27 August 2023

160

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Effects of bleomycin on progression through the cell cycle of mouse L-cells

27 August 2023

163

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Response of a murine solid tumor to in vivo combined chemotherapy and irradiation.

27 August 2023

164

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Anti-mitotic activity of bleomycin: time of action in the mammalian cell cycle

27 August 2023

165

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

Effects of bleomycin on human tongue carcinoma cells revealed by electron microscopy

27 August 2023

166

1 reference

https://api.crossref.org/works/10.1016/0163-7258(83)90022-0

27 August 2023

Identifiers

1 reference

15 August 2017

1 reference