(Q36593309)

15 August 2017

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title

Genetics of SLE in mice (English)

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15 August 2017

Dwight H Kono

1

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15 August 2017

Argyrios N Theofilopoulos

series ordinal

2

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15 August 2017

publication date

14 September 2006

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Seminars in Immunopathology

15 August 2017

published in

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15 August 2017

volume

28

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15 August 2017

issue

2

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15 August 2017

page(s)

83-96

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https://scigraph.springernature.com/pub.10.1007/s00281-006-0030-7

15 August 2017

exact match

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cites work

Separation of the New Zealand Black genetic contribution to lupus from New Zealand Black determined expansions of marginal zone B and B1a cells

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

A failure to repair self-proteins leads to T cell hyperproliferation and autoantibody production

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

Resistance to xenobiotic-induced autoimmunity maps to chromosome 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

The Sgp3 locus on mouse chromosome 13 regulates nephritogenic gp70 autoantigen expression and predisposes to autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

Dysregulated expression of the Cd22 gene as a result of a short interspersed nucleotide element insertion in Cd22a lupus-prone mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

Functional dissection of lupus susceptibility loci on the New Zealand black mouse chromosome 1: evidence for independent genetic loci affecting T and B cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

Colocalization of expansion of the splenic marginal zone population with abnormal B cell activation and autoantibody production in B6 mice with an introgressed New Zealand Black chromosome 13 interval.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

Dissection of BXSB Lupus Phenotype Using Mice Congenic for Chromosome 1 Demonstrates That Separate Intervals Direct Different Aspects of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0030-7

Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase

21 January 2018

1 reference

12 December 2020

Active inhibition of plasma cell development in resting B cells by microphthalmia-associated transcription factor

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12 December 2020

CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice

1 reference

12 December 2020

The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes

1 reference

12 December 2020

Differential effect of the autoimmune Yaa and lpr genes on the acceleration of lupus-like syndrome in MRL/MpJ mice

1 reference

12 December 2020

The P2X7 receptor is a candidate product of murine and human lupus susceptibility loci: a hypothesis and comparison of murine allelic products

1 reference

12 December 2020

Epistatic suppression of systemic lupus erythematosus: fine mapping of Sles1 to less than 1 mb

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12 December 2020

Hyperresponsive B cells in CD22-deficient mice

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12 December 2020

Autoimmunity and glomerulonephritis in mice with targeted deletion of the serum amyloid P component gene: SAP deficiency or strain combination?

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12 December 2020

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

1 reference

12 December 2020

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

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12 December 2020

Cutting Edge: Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease

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12 December 2020

The Y chromosome from autoimmune BXSB/MpJ mice induces a lupus-like syndrome in (NZW x C57BL/6)F1 male mice, but not in C57BL/6 male mice

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12 December 2020

Genetic dissection of the murine lupus susceptibility locus Sle2: contributions to increased peritoneal B-1a cells and lupus nephritis map to different loci

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12 December 2020

C1q regulatory region polymorphism down-regulating murine c1q protein levels with linkage to lupus nephritis

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12 December 2020

SLE-like autoantibodies and Sjögren's syndrome-like lymphoproliferation in TGF-beta knockout mice

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12 December 2020

Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen

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12 December 2020

Effects of mercury on the immune system.

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12 December 2020

Expression and function of Fas on cells damaged by gamma-irradiation in B6 and B6/lpr mice

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12 December 2020

Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice

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12 December 2020

The BM12 mutation and autoantibodies to dsDNA in NZB.H-2bm12 mice

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12 December 2020

Male determined accelerated autoimmune disease in BXSB mice: transfer by bone marrow and spleen cells.

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12 December 2020

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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12 December 2020

Nrf2-deficient female mice develop lupus-like autoimmune nephritis

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12 December 2020

The NOD mouse as a model of SLE.

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12 December 2020

The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development.

1 reference

12 December 2020

Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice

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12 December 2020

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

1 reference

12 December 2020

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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12 December 2020

Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase.

1 reference

12 December 2020

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

12 December 2020

T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells

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12 December 2020

Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus

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12 December 2020

The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity

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12 December 2020

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

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12 December 2020

Murine models of systemic lupus erythematosus

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12 December 2020

Features of systemic lupus erythematosus in Dnase1-deficient mice

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12 December 2020

The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

1 reference

12 December 2020

Breaking tolerance to double stranded DNA, nucleosome, and other nuclear antigens is not required for the pathogenesis of lupus glomerulonephritis

1 reference

12 December 2020

Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2

1 reference

12 December 2020

Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity

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12 December 2020

A new allele of the lpr locus, lprcg, that complements the gld gene in induction of lymphadenopathy in the mouse

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12 December 2020

Autoimmune-prone mice share a promoter haplotype associated with reduced expression and function of the Fc receptor FcgammaRII

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12 December 2020

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

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12 December 2020

Protein kinase Cδ controls self-antigen-induced B-cell tolerance

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12 December 2020

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

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12 December 2020

FcgammaRIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease

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12 December 2020

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

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12 December 2020

Genetics of lupus nephritis

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12 December 2020

Comparative expression of TNF-alpha alleles from normal and autoimmune-prone MHC haplotypes

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12 December 2020

C1q and systemic lupus erythematosus

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12 December 2020

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

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12 December 2020

Delineating the genetic basis of systemic lupus erythematosus

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12 December 2020

Studies of consomic mice bearing the Y chromosome of the BXSB mouse

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12 December 2020

Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation

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12 December 2020

Update on human systemic lupus erythematosus genetics

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12 December 2020

Overexpression of CD40 ligand in murine epidermis results in chronic skin inflammation and systemic autoimmunity

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12 December 2020

The APO-1/Fas (CD95) receptor is expressed in homozygous MRL/lpr mice

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12 December 2020

Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies

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12 December 2020

A y chromosome associated factor in strain bxsb producing accelerated autoimmunity and lymphoproliferation

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12 December 2020

Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1.

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12 December 2020

Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA.

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12 December 2020

Mouse models of human autoimmune diseases: essential tools that require the proper controls

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12 December 2020

H-2-linked control of the Yaa gene-induced acceleration of lupus-like autoimmune disease in BXSB mice

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12 December 2020

Epistatic modifiers of autoimmunity in a murine model of lupus nephritis

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12 December 2020

Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

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12 December 2020

Illuminating autoimmune regulators through controlled variation of the mouse genome sequence

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12 December 2020

Gadd45 beta and Gadd45 gamma are critical for regulating autoimmunity

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12 December 2020

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

12 December 2020

Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus

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12 December 2020

An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

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12 December 2020

The Yaa Gene Model of Systemic Lupus Erythematosus

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12 December 2020

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

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12 December 2020

Genetic underpinnings of autoimmunity--lessons from studies in arthritis, diabetes, lupus and multiple sclerosis

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12 December 2020

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

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12 December 2020

Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus

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12 December 2020

Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection

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12 December 2020

Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice

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12 December 2020

Impaired Fas response and autoimmunity in Pten+/- mice

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12 December 2020

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

1 reference

12 December 2020

Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity

1 reference

12 December 2020

Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice

1 reference

12 December 2020

Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

1 reference

12 December 2020

The mosaic structure of variation in the laboratory mouse genome

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12 December 2020

Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus.

1 reference

12 December 2020

Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) acts as a regulator of B-cell development, B-cell antigen receptor (BCR)-mediated activation, and autoimmune disease

1 reference

12 December 2020

Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice

1 reference

12 December 2020

Overlapping BXSB congenic intervals, in combination with microarray gene expression, reveal novel lupus candidate genes

1 reference

12 December 2020

Genetics of systemic lupus erythematosus: how far have we come?

1 reference

12 December 2020

A Tlr7 translocation accelerates systemic autoimmunity in murine lupus

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12 December 2020

New insights into disease pathogenesis from mouse lupus genetics

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12 December 2020

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

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12 December 2020

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

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12 December 2020

Defective T cell activation and autoimmune disorder in Stra13-deficient mice

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12 December 2020

Dissection of the effects of tumor necrosis factor-alpha and class II gene polymorphisms within the MHC on murine systemic lupus erythematosus (SLE)

1 reference

12 December 2020

Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis

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12 December 2020

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

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12 December 2020

The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn

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12 December 2020

Polymorphisms in IgG Fc receptor IIB regulatory regions associated with autoimmune susceptibility

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12 December 2020

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

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12 December 2020

Genetic Segregation of Spontaneous Erosive Arthritis and Generalized Autoimmune Disease in the BXD2 Recombinant Inbred Strain of Mice

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12 December 2020

Differential role of three major New Zealand Black-derived loci linked with Yaa-induced murine lupus nephritis.

1 reference

12 December 2020

Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus

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12 December 2020

Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family

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12 December 2020

Genetic dissection of systemic lupus erythematosus pathogenesis: evidence for functional expression of Sle3/5 by non-T cells

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12 December 2020

Genetically determined aberrant down-regulation of FcgammaRIIB1 in germinal center B cells associated with hyper-IgG and IgG autoantibodies in murine systemic lupus erythematosus

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12 December 2020

Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome.

1 reference

12 December 2020

Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome

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12 December 2020

Mutational analysis of TNF-alpha gene reveals a regulatory role for the 3'-untranslated region in the genetic predisposition to lupus-like autoimmune disease.

1 reference

12 December 2020

T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis

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12 December 2020

Autoimmune alterations induced by the New Zealand Black Lbw2 locus in BWF1 mice

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12 December 2020

Characterization of the non-functional Fas ligand of gld mice

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12 December 2020

A LAT mutation that inhibits T cell development yet induces lymphoproliferation

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12 December 2020

Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

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12 December 2020

Polymorphism and chromosomal mapping of the mouse gene for B-cell activating factor belonging to the tumor necrosis factor family (Baff) and association with the autoimmune phenotype

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12 December 2020

Genealogies of mouse inbred strains

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12 December 2020

Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes.

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12 December 2020

A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice

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12 December 2020

Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene

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12 December 2020

The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT

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12 December 2020

Genetic remodeling of protein glycosylation in vivo induces autoimmune disease

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12 December 2020

Regulation of B cell tolerance by the lupus susceptibility gene Ly108.

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12 December 2020

Analysis of restriction fragment length polymorphism in lymphokine genes of normal and autoimmune mice

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12 December 2020

Genetic dissection of vasculitis in MRL/lpr lupus mice: a novel susceptibility locus involving the CD72c allele

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12 December 2020

Linkage analysis of systemic lupus erythematosus induced in diabetes-prone nonobese diabetic mice by Mycobacterium bovis

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12 December 2020

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

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12 December 2020

The role of complement in B cell activation and tolerance.

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12 December 2020

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

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12 December 2020

Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein

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12 December 2020

A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen

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12 December 2020

Prevention of murine lupus by an I-E alpha chain transgene: protective role of I-E alpha chain-derived peptides with a high affinity to I-Ab molecules

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12 December 2020

Impaired T cell death and lupus-like autoimmunity in T cell-specific adapter protein-deficient mice

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12 December 2020

Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor

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12 December 2020

Aiolos regulates B cell activation and maturation to effector state

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12 December 2020

10.1007/S00281-006-0030-7

Identifiers

DOI

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15 August 2017

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