(Q36596696)

15 August 2017

1 reference

title

The vitamin D receptor as a therapeutic target (English)

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15 August 2017

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Moray J Campbell

1

1 reference

15 August 2017

Luciano Adorini

series ordinal

2

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15 August 2017

language of work or name

English

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publication date

1 October 2006

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Expert Opinion on Therapeutic Targets

15 August 2017

published in

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15 August 2017

volume

10

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15 August 2017

issue

5

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15 August 2017

page(s)

735-748

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Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR.

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Nuclear receptors: overview and classification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Enhancers located within two introns of the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Regulation of multiple insulin-like growth factor binding protein genes by 1alpha,25-dihydroxyvitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Role of Sp1, C/EBP alpha, HNF3, and PXR in the basal- and xenobiotic-mediated regulation of the CYP3A4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

An essential role of the CAAT/enhancer binding protein-alpha in the vitamin D-induced expression of the human steroid/bile acid-sulfotransferase (SULT2A1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Regulation of rat cytochrome P450C24 (CYP24) gene expression. Evidence for functional cooperation of Ras-activated Ets transcription factors with the vitamin D receptor in 1,25-dihydroxyvitamin D(3)-mediated induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)2-vitamin D3 in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Cellular functions of plasma membrane estrogen receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Nuclear import of the retinoid X receptor, the vitamin D receptor, and their mutual heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Mechanism of the nuclear receptor molecular switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1alpha,25-Dihydroxyvitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

N-CoR controls differentiation of neural stem cells into astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Molecular determinants for the tissue specificity of SERMs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Altered SMRT levels disrupt vitamin D3 receptor signalling in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Histone acetylation as an epigenetic determinant of long-term transcriptional competence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Cellular memory and the histone code

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

The histone-binding code of nuclear receptor co-repressors matches the substrate specificity of histone deacetylase 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Methylation of histone H4 at arginine 3 occurs in vivo and is mediated by the nuclear receptor coactivator PRMT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Histone H4-K16 acetylation controls chromatin structure and protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Estimates of optimal vitamin D status

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Molecular determinants of resistance to antiandrogen therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Ligand-induced transrepression by VDR through association of WSTF with acetylated histones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Accelerated mammary gland development during pregnancy and delayed postlactational involution in vitamin D3 receptor null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Calcium and 1,25(OH)2D: interacting drivers of epidermal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Epithelial stem cells in human prostate growth and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Generation of a functional mammary gland from a single stem cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

1-alpha,25-Dihydroxyvitamin D3 (1,25(OH)(2)D(3)) hampers the maturation of fully active immature dendritic cells from monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D(3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Dendritic cells as key targets for immunomodulation by Vitamin D receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Dendritic cell modulation by 1alpha,25 dihydroxyvitamin D3 and its analogs: a vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Comparative genome analysis identifies the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

The anti-proliferative effects of 1alpha,25(OH)2D3 on breast and prostate cancer cells are associated with induction of BRCA1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Gadd45a contributes to p53 stabilization in response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

1alpha,25-dihydroxyvitamin D(3) (calcitriol) and its analogue, 19-nor-1alpha,25(OH)(2)D(2), potentiate the effects of ionising radiation on human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Possible role for vitamin D in controlling breast cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Impact of the Vitamin D3 receptor on growth-regulatory pathways in mammary gland and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Novel 20-epi-vitamin D3 analog combined with 9-cis-retinoic acid markedly inhibits colony growth of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Microarray analysis of 1alpha,25-dihydroxyvitamin D3-treated MC3T3-E1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Vitamin D3 receptor/Sp1 complex is required for the induction of p27Kip1 expression by vitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

p27(Kip1) stabilization and G(1) arrest by 1,25-dihydroxyvitamin D(3) in ovarian cancer cells mediated through down-regulation of cyclin E/cyclin-dependent kinase 2 and Skp1-Cullin-F-box protein/Skp2 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

G2/M arrest by 1,25-dihydroxyvitamin D3 in ovarian cancer cells mediated through the induction of GADD45 via an exonic enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Vitamin D3 up-regulating protein 1 (VDUP1) antisense DNA regulates tumorigenicity and melanogenesis of murine melanoma cells via regulating the expression of fas ligand and reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Vitamin D receptor status alters mammary gland morphology and tumorigenesis in MMTV-neu mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

A protective role of 1,25-dihydroxyvitamin D3 in chemically induced rat colon carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Rationale for the development and current status of calcitriol in androgen-independent prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Phase II trial of high-dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) and dexamethasone in androgen-independent prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Pharmacokinetics and tolerability of a single dose of DN-101, a new formulation of calcitriol, in patients with cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

ASCENT: the androgen-independent prostate cancer study of calcitriol enhancing taxotere

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Intervention in autoimmunity: the potential of vitamin D receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Systematic review of comparative efficacy and tolerability of calcipotriol in treating chronic plaque psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Effect of vitamin D3 on the increased expression of Bcl-xL in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Vitamin D as immunomodulatory therapy for kidney transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Inhibition of acute and chronic allograft rejection in mouse models by BXL-628, a nonhypercalcemic vitamin D receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Prevention of chronic allograft rejection by Vitamin D receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Sun exposure, vitamin D receptor gene polymorphisms, and risk of advanced prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

The epidemiology of vitamin D and cancer incidence and mortality: a review (United States).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Geographic variation in breast cancer mortality in the United States: a hypothesis involving exposure to solar radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Do sunlight and vitamin D reduce the likelihood of colon cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Plasma 25-hydroxy vitamin D concentrations, vitamin D receptor genotype and breast cancer risk in a UK Caucasian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Autocrine metabolism of vitamin D in normal and malignant breast tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Vitamin D and autoimmunity: is vitamin D status an environmental factor affecting autoimmune disease prevalence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Integrity of the 1,25-dihydroxyvitamin D3 receptor in bone, lung, and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Resistance of HBL100 human breast epithelial cells to vitamin D action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Vitamin D receptor content and transcriptional activity do not fully predict antiproliferative effects of vitamin D in human prostate cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

SNAIL vs vitamin D receptor expression in colon cancer: therapeutics implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

The molecular basis of vitamin D receptor and beta-catenin crossregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Vitamin D receptor gene polymorphisms and breast cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Genetics and biology of vitamin D receptor polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Association of the vitamin D receptor genotype with bone metastases in breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

1,25-Dihydroxycholecalciferol enhances butyrate-induced p21(Waf1/Cip1) expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Butyrate-induced differentiation of Caco-2 cells is mediated by vitamin D receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

High-dose calcitriol and carboplatin in metastatic androgen-independent prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Anti-tumor activity of calcitriol: pre-clinical and clinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

BXL628, a novel vitamin D3 analog arrests prostate growth in patients with benign prostatic hyperplasia: a randomized clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Human bladder as a novel target for vitamin D receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Inhibition of prostate cell growth by BXL-628, a calcitriol analogue selected for a phase II clinical trial in patients with benign prostate hyperplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

The evolution of molecular biology into systems biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Nutrigenomics: goals and strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

Cell biology: Nondisjunction, aneuploidy and tetraploidy (Reply)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.5.735

10.1517/14728222.10.5.735

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference