(Q36604872)

15 August 2017

DNA-dependent PK inhibits adeno-associated virus DNA integration (English)

1 reference

15 August 2017

Sihong Song

1

1 reference

15 August 2017

Yuanqing Lu

2

1 reference

15 August 2017

Young-Kook Choi

3

1 reference

15 August 2017

Yinong Han

4

1 reference

15 August 2017

Qiushi Tang

5

1 reference

15 August 2017

Ge Zhao

6

1 reference

15 August 2017

Kenneth I Berns

7

1 reference

15 August 2017

Terence R Flotte

8

1 reference

15 August 2017

language of work or name

English

0 references

publication date

6 February 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

101

1 reference

15 August 2017

7

1 reference

15 August 2017

2112-2116

1 reference

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

AAV serotype 2 vectors preferentially integrate into active genes in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Consequences of DNA-dependent protein kinase catalytic subunit deficiency on recombinant adeno-associated virus genome circularization and heterodimerization in muscle tissue

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Genetic fate of recombinant adeno-associated virus vector genomes in muscle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Adeno-associated virus (AAV) site-specific integration: formation of AAV-AAVS1 junctions in an in vitro system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

The DNA-dependent protein kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

DNA looping by Ku and the DNA-dependent protein kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Recombinant adeno-associated virus (AAV-CFTR) vectors do not integrate in a site-specific fashion in an immortalized epithelial cell line.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

In vivo model of adeno-associated virus vector persistence and rescue

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Analysis of the mechanism of interaction of simian Ku protein with DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

The nuclear serine/threonine protein kinase DNA-PK

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357060

Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors

30 September 2017

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307833100

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307833100

Intramuscular administration of recombinant adeno-associated virus 2 alpha-1 antitrypsin (rAAV-SERPINA1) vectors in a nonhuman primate model: safety and immunologic aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307833100

Pathways of removal of free DNA vector ends in normal and DNA-PKcs-deficient SCID mouse hepatocytes transduced with rAAV vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307833100

Virus-mediated killing of cells that lack p53 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307833100

Double strand interaction is the predominant pathway for intermolecular recombination of adeno-associated viral genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307833100

Functional properties of the separate subunits of human DNA helicase II/Ku autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307833100

HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307833100

AAV loves an active genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0307833100

Looking into the safety of AAV vectors

21 January 2018

1 reference

12 December 2020

Mechanism of interaction between Ku protein and DNA

1 reference

12 December 2020

Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA

1 reference

12 December 2020

Ku selectively transfers between DNA molecules with homologous ends

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0307833100

1 reference

15 August 2017

0 references

1 reference

15 August 2017

1 reference