(Q36605057)

15 August 2017

Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells (English)

1 reference

15 August 2017

2

1 reference

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13 June 2020

Leanna S Morinishi

6

1 reference

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13 June 2020

author name string

Michael Ramirez

1

1 reference

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13 June 2020

Robert J Steininger

3

1 reference

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13 June 2020

Daria Osipchuk

4

1 reference

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13 June 2020

Maike A Roth

5

1 reference

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13 June 2020

Louise Evans

7

1 reference

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13 June 2020

Weiyue Ji

8

1 reference

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13 June 2020

Chien-Hsiang Hsu

9

1 reference

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13 June 2020

Kevin Thurley

10

1 reference

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13 June 2020

Shuguang Wei

11

1 reference

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13 June 2020

Anwu Zhou

12

1 reference

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13 June 2020

Prasad R Koduru

13

1 reference

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13 June 2020

Bruce A Posner

14

1 reference

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13 June 2020

Lani F Wu

15

1 reference

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13 June 2020

Steven J Altschuler

16

1 reference

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13 June 2020

language of work or name

English

0 references

publication date

19 February 2016

1 reference

15 August 2017

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26891683%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

7

1 reference

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13 June 2020

page(s)

10690

1 reference

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Creative Commons Attribution 4.0 International

13 June 2020

copyright license

start time

19 February 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms10690

0 references

cites work

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

1 reference

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The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma.

30 September 2017

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Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non-Small Cell Lung Cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

AKT inactivation causes persistent drug tolerance to EGFR inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models

30 September 2017

1 reference

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Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.

30 September 2017

1 reference

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Robust dose-response curve estimation applied to high content screening data analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors

30 September 2017

1 reference

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Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

30 September 2017

1 reference

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Acquired resistance to TKIs in solid tumours: learning from lung cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Bypass mechanisms of resistance to receptor tyrosine kinase inhibition in lung cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Metrics other than potency reveal systematic variation in responses to cancer drugs.

30 September 2017

1 reference

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Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance

30 September 2017

1 reference

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Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

30 September 2017

1 reference

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Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors.

30 September 2017

1 reference

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Nonheritable cellular variability accelerates the evolutionary processes of cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Converting cancer therapies into cures: lessons from infectious diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

30 September 2017

1 reference

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Second-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs): a better mousetrap? A review of the clinical evidence

30 September 2017

1 reference

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Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.

30 September 2017

1 reference

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Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling

30 September 2017

1 reference

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"Persisters": survival at the cellular level

30 September 2017

1 reference

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Exome sequencing-based copy-number variation and loss of heterozygosity detection: ExomeCNV

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

30 September 2017

1 reference

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Fast and accurate long-read alignment with Burrows-Wheeler transform

30 September 2017

1 reference

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Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

DNA polymerase POLN participates in cross-link repair and homologous recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Tumor heterogeneity: causes and consequences

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Cancer-specific mutations in PIK3CA are oncogenic in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Bacterial persistence as a phenotypic switch

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Sensitivity to gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/Akt pathway for proliferation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

High-throughput tissue microarray analysis of 3p25 (RAF1) and 8p12 (FGFR1) copy number alterations in urinary bladder cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

Mechanisms of Resistance to Epidermal Growth Factor Receptor Inhibitors and Novel Therapeutic Strategies to Overcome Resistance in NSCLC Patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762880

20 September 2018

Identifiers

DOI

10.1038/NCOMMS10690

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26891683%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26891683%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26891683%20AND%20SRC:MED&resulttype=core&format=json