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The molecular mechanisms of skeletal muscle wasting: implications for therapy.
scientific article published on October 2006
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scholarly article
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Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
review article
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Europe PubMed Central
title
The molecular mechanisms of skeletal muscle wasting: implications for therapy
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
author
Grant D. Stewart
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2
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Europe PubMed Central
PubMed publication ID
17009546
reference URL
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20 December 2019
author name string
R J E Skipworth
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1
1 reference
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Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
J A Ross
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3
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Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
D C Guttridge
series ordinal
4
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Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
K C H Fearon
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
publication date
1 October 2006
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Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
published in
Journal of the Royal College of Surgeons of Edinburgh
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
volume
4
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Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
issue
5
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Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
page(s)
273-283
1 reference
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Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
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20 December 2019
cites work
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
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Accelerated nitrogen loss after traumatic injury is not attenuated by achievement of energy balance
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Myopathies in critical illness: characterization and nutritional aspects
1 reference
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Crossref
reference URL
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7 January 2021
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Short-term bed rest impairs amino acid-induced protein anabolism in humans.
1 reference
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Crossref
reference URL
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7 January 2021
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Metabolic consequences of physical inactivity
1 reference
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7 January 2021
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Cancer cachexia and fatigue.
1 reference
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7 January 2021
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Why do patients with weight loss have a worse outcome when undergoing chemotherapy for gastrointestinal malignancies?
1 reference
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Tumor necrosis factor-regulated biphasic activation of NF-kappa B is required for cytokine-induced loss of skeletal muscle gene products
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
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NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
retrieved
7 January 2021
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inferred from DOI database lookup
IKKbeta/NF-kappaB activation causes severe muscle wasting in mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions
1 reference
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Crossref
reference URL
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7 January 2021
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Xanthine oxidase inhibition for chronic heart failure: is allopurinol the next therapeutic advance in heart failure?
1 reference
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Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging
1 reference
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Crossref
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Calpain-1-sensitive myofibrillar proteins of the human myocardium.
1 reference
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Crossref
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7 January 2021
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Expression of a calpastatin transgene slows muscle wasting and obviates changes in myosin isoform expression during murine muscle disuse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
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inferred from DOI database lookup
Calpain-3 gene expression is decreased during experimental cancer cachexia
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Muscle fibre atrophy in critically ill patients is associated with the loss of myosin filaments and the presence of lysosomal enzymes and ubiquitin
1 reference
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Crossref
reference URL
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7 January 2021
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Dexamethasone stimulates proteasome- and calcium-dependent proteolysis in cultured L6 myotubes.
1 reference
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Crossref
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7 January 2021
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Increased expression of proteasome subunits in skeletal muscle of cancer patients with weight loss.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of ubiquitin ligases required for skeletal muscle atrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia
1 reference
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Crossref
reference URL
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7 January 2021
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Dystrophin glycoprotein complex dysfunction: A regulatory link between muscular dystrophy and cancer cachexia
1 reference
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Crossref
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inferred from DOI database lookup
Proteasome inhibitor bortezomib for the treatment of multiple myeloma.
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inferred from DOI database lookup
Reduction of skeletal muscle atrophy by a proteasome inhibitor in a rat model of denervation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
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Is bortezomib, a proteasome inhibitor, effective in treating cancer-associated weight loss? Preliminary results from the North Central Cancer Treatment Group
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Crossref
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Tripeptidyl-peptidase II expression and activity are increased in skeletal muscle during sepsis
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of cancer cachexia on the activity of tripeptidyl-peptidase II in skeletal muscle
1 reference
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Crossref
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Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure
1 reference
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1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Ghrelin increases energy intake in cancer patients with impaired appetite: acute, randomized, placebo-controlled trial
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Prognostic importance of insulin-mediated glucose uptake in aged patients with congestive heart failure secondary to mitral and/or aortic valve disease.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
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inferred from DOI database lookup
The response of leptin, interleukin-6 and fat oxidation to feeding in weight-losing patients with pancreatic cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
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inferred from DOI database lookup
Sepsis and inflammatory insults downregulate IGFBP-5, but not IGFBP-4, in skeletal muscle via a TNF-dependent mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
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inferred from DOI database lookup
Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
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inferred from DOI database lookup
The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: the Rancho Bernardo Study
1 reference
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7 January 2021
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inferred from DOI database lookup
The possible role of myostatin in skeletal muscle atrophy and cachexia.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
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inferred from DOI database lookup
Myostatin Knockout in Mice Increases Myogenesis and Decreases Adipogenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
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inferred from DOI database lookup
Loss of myostatin attenuates severity of muscular dystrophy in mdx mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Myostatin mutation associated with gross muscle hypertrophy in a child
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic importance of weight loss in chronic heart failure and the effect of treatment with angiotensin-converting-enzyme inhibitors: an observational study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1479-666X%2806%2980004-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1479-666X(06)80004-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
PubMed publication ID
17009546
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17009546
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17009546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 December 2019
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